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TPD52L1 (TPD52 like 1)

Gene

7164

TPD52 like 1

TPD52L1

D53, TPD53

6q22.31

This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase

Show/Hide all(223)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018898	hsa-miR-335-5p	Microarray	18185580
MIRT499298	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT499297	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT499296	hsa-miR-429	PAR-CLIP	24398324
MIRT238793	hsa-miR-8066	PAR-CLIP	24398324
MIRT499294	hsa-miR-4724-5p	PAR-CLIP	24398324
MIRT499295	hsa-miR-6513-3p	PAR-CLIP	24398324
MIRT238790	hsa-miR-203a-3p	PAR-CLIP	24398324
MIRT499293	hsa-miR-8069	PAR-CLIP	24398324
MIRT443346	hsa-miR-3173-3p	PAR-CLIP	22100165
MIRT443344	hsa-miR-6891-5p	PAR-CLIP	22100165
MIRT443345	hsa-miR-548p	PAR-CLIP	22100165
MIRT443342	hsa-miR-4695-5p	PAR-CLIP	22100165
MIRT443343	hsa-miR-5589-3p	PAR-CLIP	22100165
MIRT499298	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT499297	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT499296	hsa-miR-429	PAR-CLIP	24398324
MIRT238793	hsa-miR-8066	PAR-CLIP	24398324
MIRT499294	hsa-miR-4724-5p	PAR-CLIP	24398324
MIRT499295	hsa-miR-6513-3p	PAR-CLIP	24398324
MIRT238790	hsa-miR-203a-3p	PAR-CLIP	24398324
MIRT499293	hsa-miR-8069	PAR-CLIP	24398324
MIRT443346	hsa-miR-3173-3p	PAR-CLIP	22100165
MIRT443344	hsa-miR-6891-5p	PAR-CLIP	22100165
MIRT443345	hsa-miR-548p	PAR-CLIP	22100165
MIRT443342	hsa-miR-4695-5p	PAR-CLIP	22100165
MIRT443343	hsa-miR-5589-3p	PAR-CLIP	22100165
MIRT1449115	hsa-miR-1261	CLIP-seq
MIRT1449116	hsa-miR-1273f	CLIP-seq
MIRT1449117	hsa-miR-1287	CLIP-seq
MIRT1449118	hsa-miR-1290	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449120	hsa-miR-133a	CLIP-seq
MIRT1449121	hsa-miR-133b	CLIP-seq
MIRT1449122	hsa-miR-137	CLIP-seq
MIRT1449123	hsa-miR-1587	CLIP-seq
MIRT1449124	hsa-miR-200b	CLIP-seq
MIRT1449125	hsa-miR-200c	CLIP-seq
MIRT1449126	hsa-miR-203	CLIP-seq
MIRT1449127	hsa-miR-302f	CLIP-seq
MIRT1449128	hsa-miR-3126-3p	CLIP-seq
MIRT1449129	hsa-miR-3132	CLIP-seq
MIRT1449130	hsa-miR-3135b	CLIP-seq
MIRT1449131	hsa-miR-3143	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449134	hsa-miR-4492	CLIP-seq
MIRT1449135	hsa-miR-4498	CLIP-seq
MIRT1449136	hsa-miR-4501	CLIP-seq
MIRT1449137	hsa-miR-4504	CLIP-seq
MIRT1449138	hsa-miR-4505	CLIP-seq
MIRT1449139	hsa-miR-4514	CLIP-seq
MIRT1449140	hsa-miR-4645-3p	CLIP-seq
MIRT1449141	hsa-miR-4656	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449143	hsa-miR-4668-3p	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449145	hsa-miR-4675	CLIP-seq
MIRT1449146	hsa-miR-4692	CLIP-seq
MIRT1449147	hsa-miR-4741	CLIP-seq
MIRT1449148	hsa-miR-4756-3p	CLIP-seq
MIRT1449149	hsa-miR-4778-3p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449151	hsa-miR-4793-5p	CLIP-seq
MIRT1449152	hsa-miR-4803	CLIP-seq
MIRT1449153	hsa-miR-542-3p	CLIP-seq
MIRT1449154	hsa-miR-628-5p	CLIP-seq
MIRT1449155	hsa-miR-762	CLIP-seq
MIRT1449156	hsa-miR-1206	CLIP-seq
MIRT1449115	hsa-miR-1261	CLIP-seq
MIRT1449116	hsa-miR-1273f	CLIP-seq
MIRT1449118	hsa-miR-1290	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449158	hsa-miR-1298	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449120	hsa-miR-133a	CLIP-seq
MIRT1449121	hsa-miR-133b	CLIP-seq
MIRT1449123	hsa-miR-1587	CLIP-seq
MIRT1449124	hsa-miR-200b	CLIP-seq
MIRT1449125	hsa-miR-200c	CLIP-seq
MIRT1449126	hsa-miR-203	CLIP-seq
MIRT1449159	hsa-miR-221	CLIP-seq
MIRT1449160	hsa-miR-222	CLIP-seq
MIRT1449128	hsa-miR-3126-3p	CLIP-seq
MIRT1449129	hsa-miR-3132	CLIP-seq
MIRT1449161	hsa-miR-3148	CLIP-seq
MIRT1449162	hsa-miR-3157-5p	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT1449164	hsa-miR-3199	CLIP-seq
MIRT1449165	hsa-miR-330-3p	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449166	hsa-miR-3614-3p	CLIP-seq
MIRT1449167	hsa-miR-3662	CLIP-seq
MIRT1449168	hsa-miR-3677-5p	CLIP-seq
MIRT1449169	hsa-miR-3922-5p	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449170	hsa-miR-3978	CLIP-seq
MIRT1449171	hsa-miR-4446-5p	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449173	hsa-miR-4475	CLIP-seq
MIRT1449134	hsa-miR-4492	CLIP-seq
MIRT1449135	hsa-miR-4498	CLIP-seq
MIRT1449137	hsa-miR-4504	CLIP-seq
MIRT1449138	hsa-miR-4505	CLIP-seq
MIRT1449139	hsa-miR-4514	CLIP-seq
MIRT1449140	hsa-miR-4645-3p	CLIP-seq
MIRT1449141	hsa-miR-4656	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449174	hsa-miR-4666-5p	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449145	hsa-miR-4675	CLIP-seq
MIRT1449146	hsa-miR-4692	CLIP-seq
MIRT1449147	hsa-miR-4741	CLIP-seq
MIRT1449148	hsa-miR-4756-3p	CLIP-seq
MIRT1449149	hsa-miR-4778-3p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449175	hsa-miR-488	CLIP-seq
MIRT1449153	hsa-miR-542-3p	CLIP-seq
MIRT1449176	hsa-miR-548c-3p	CLIP-seq
MIRT1449177	hsa-miR-629	CLIP-seq
MIRT1449178	hsa-miR-661	CLIP-seq
MIRT1449155	hsa-miR-762	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq
MIRT1449156	hsa-miR-1206	CLIP-seq
MIRT1449116	hsa-miR-1273f	CLIP-seq
MIRT1449117	hsa-miR-1287	CLIP-seq
MIRT1449158	hsa-miR-1298	CLIP-seq
MIRT2134369	hsa-miR-1299	CLIP-seq
MIRT2134370	hsa-miR-1301	CLIP-seq
MIRT1449122	hsa-miR-137	CLIP-seq
MIRT1449123	hsa-miR-1587	CLIP-seq
MIRT1449129	hsa-miR-3132	CLIP-seq
MIRT1449130	hsa-miR-3135b	CLIP-seq
MIRT1449162	hsa-miR-3157-5p	CLIP-seq
MIRT2134371	hsa-miR-3184	CLIP-seq
MIRT1449164	hsa-miR-3199	CLIP-seq
MIRT2134372	hsa-miR-3545-3p	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449166	hsa-miR-3614-3p	CLIP-seq
MIRT1449168	hsa-miR-3677-5p	CLIP-seq
MIRT2134373	hsa-miR-423-5p	CLIP-seq
MIRT1449173	hsa-miR-4475	CLIP-seq
MIRT1449134	hsa-miR-4492	CLIP-seq
MIRT1449135	hsa-miR-4498	CLIP-seq
MIRT1449138	hsa-miR-4505	CLIP-seq
MIRT2134374	hsa-miR-4539	CLIP-seq
MIRT1449141	hsa-miR-4656	CLIP-seq
MIRT2134375	hsa-miR-4660	CLIP-seq
MIRT1449145	hsa-miR-4675	CLIP-seq
MIRT2134376	hsa-miR-4686	CLIP-seq
MIRT2134377	hsa-miR-4709-3p	CLIP-seq
MIRT1449147	hsa-miR-4741	CLIP-seq
MIRT2134378	hsa-miR-4743	CLIP-seq
MIRT1449148	hsa-miR-4756-3p	CLIP-seq
MIRT2134379	hsa-miR-4766-5p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449151	hsa-miR-4793-5p	CLIP-seq
MIRT1449175	hsa-miR-488	CLIP-seq
MIRT2134380	hsa-miR-5047	CLIP-seq
MIRT2134381	hsa-miR-516b	CLIP-seq
MIRT1449155	hsa-miR-762	CLIP-seq
MIRT1449156	hsa-miR-1206	CLIP-seq
MIRT2355632	hsa-miR-1244	CLIP-seq
MIRT1449115	hsa-miR-1261	CLIP-seq
MIRT2355633	hsa-miR-1267	CLIP-seq
MIRT1449117	hsa-miR-1287	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449158	hsa-miR-1298	CLIP-seq
MIRT2134369	hsa-miR-1299	CLIP-seq
MIRT1449120	hsa-miR-133a	CLIP-seq
MIRT1449121	hsa-miR-133b	CLIP-seq
MIRT1449122	hsa-miR-137	CLIP-seq
MIRT1449124	hsa-miR-200b	CLIP-seq
MIRT1449125	hsa-miR-200c	CLIP-seq
MIRT1449126	hsa-miR-203	CLIP-seq
MIRT1449128	hsa-miR-3126-3p	CLIP-seq
MIRT1449130	hsa-miR-3135b	CLIP-seq
MIRT1449162	hsa-miR-3157-5p	CLIP-seq
MIRT2355634	hsa-miR-3171	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT2134371	hsa-miR-3184	CLIP-seq
MIRT1449164	hsa-miR-3199	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449166	hsa-miR-3614-3p	CLIP-seq
MIRT1449167	hsa-miR-3662	CLIP-seq
MIRT1449169	hsa-miR-3922-5p	CLIP-seq
MIRT2134373	hsa-miR-423-5p	CLIP-seq
MIRT2355635	hsa-miR-4259	CLIP-seq
MIRT1449171	hsa-miR-4446-5p	CLIP-seq
MIRT2355636	hsa-miR-4457	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449136	hsa-miR-4501	CLIP-seq
MIRT1449137	hsa-miR-4504	CLIP-seq
MIRT1449140	hsa-miR-4645-3p	CLIP-seq
MIRT2355637	hsa-miR-4703-3p	CLIP-seq
MIRT2134377	hsa-miR-4709-3p	CLIP-seq
MIRT2355638	hsa-miR-4715-5p	CLIP-seq
MIRT1449149	hsa-miR-4778-3p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449151	hsa-miR-4793-5p	CLIP-seq
MIRT2355639	hsa-miR-513b	CLIP-seq
MIRT2134381	hsa-miR-516b	CLIP-seq
MIRT1449153	hsa-miR-542-3p	CLIP-seq
MIRT1449177	hsa-miR-629	CLIP-seq
MIRT1449178	hsa-miR-661	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT1449167	hsa-miR-3662	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	IDA	16112108
GO:0005515	Function	Protein binding	IPI	9484778, 12963375, 14761963
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	12963375, 16112108
GO:0042802	Function	Identical protein binding	IPI	9484778
GO:0042803	Function	Protein homodimerization activity	IDA	9484778
GO:0043406	Process	Positive regulation of MAP kinase activity	IBA	21873635
GO:0043406	Process	Positive regulation of MAP kinase activity	IDA	14761963
GO:0046330	Process	Positive regulation of JNK cascade	IDA	14761963
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	12963375, 16112108
GO:2001235	Process	Positive regulation of apoptotic signaling pathway	IBA	21873635
GO:2001235	Process	Positive regulation of apoptotic signaling pathway	IDA	14761963

MIM	HGNC	e!Ensembl
604069	12006	ENSG00000111907

Protein

UniProt ID

Q16890

Protein name

Tumor protein D53 (hD53) (Tumor protein D52-like 1)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04201	TPD52	9 → 187	Tumour protein D52 family	Family

Sequence

MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAK
ERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTA
ISKKFGDMSYSIRHSISMPAMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLS
STAHASAQSLAGGSRRTKEEELQC

Sequence length

204

Interactions

View interactions

	Reactome
			Golgi Associated Vesicle Biogenesis

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	17013881

Show/Hide Unknown Diseases (1)

Unknown
Disease name	Disease term	dbSNP ID	References
Prostatic neoplasms	Prostatic Neoplasms		17013881

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