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TNFAIP3 (TNF alpha induced protein 3)

Gene

7128

TNF alpha induced protein 3

TNFAIP3

A20, AIFBL1, AISBL, OTUD7C, TNFA1P2

6q23.3

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well a

Show/Hide all(9)

SNP ID	Visualize variation	Clinical significance	Consequence
rs864321625	T>A	Pathogenic	Stop gained, coding sequence variant
rs864321626	C>T	Pathogenic	Stop gained, coding sequence variant
rs864321682	T>-	Pathogenic	Frameshift variant, coding sequence variant
rs864321683	G>-	Pathogenic	Frameshift variant, coding sequence variant
rs864321684	C>G	Pathogenic	Stop gained, coding sequence variant
rs864321685	G>-	Pathogenic	Frameshift variant, coding sequence variant
rs1064796470	CT>-	Pathogenic	Coding sequence variant, frameshift variant
rs1554225021	T>C	Pathogenic	Missense variant, coding sequence variant
rs1582892979	GGAG>AGGAA	Pathogenic	Coding sequence variant, frameshift variant

Show/Hide all(469)

miRTarBase ID	miRNA	Experiments	Reference
MIRT005955	hsa-miR-21-5p	Luciferase reporter assay	21131358
MIRT005955	hsa-miR-21-5p	Luciferase reporter assay	21131358
MIRT006380	hsa-miR-29a-3p	Luciferase reporter assay	21763284
MIRT006380	hsa-miR-29a-3p	Luciferase reporter assay	21763284
MIRT006471	hsa-miR-125a-5p	qRT-PCR, Western blot	22550173
MIRT006472	hsa-miR-125b-5p	qRT-PCR, Western blot	22550173
MIRT006380	hsa-miR-29a-3p	Luciferase reporter assay	21763284
MIRT006472	hsa-miR-125b-5p	qRT-PCR, Western blot	22550173
MIRT029863	hsa-miR-26b-5p	Microarray	19088304
MIRT030581	hsa-miR-24-3p	Microarray	19748357
MIRT621770	hsa-miR-5700	HITS-CLIP	23824327
MIRT621769	hsa-miR-2278	HITS-CLIP	23824327
MIRT621768	hsa-miR-586	HITS-CLIP	23824327
MIRT621767	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT621766	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT621765	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT621764	hsa-miR-520g-5p	HITS-CLIP	23824327
MIRT621763	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT621762	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT621761	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT621760	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT621759	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT621758	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT621757	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT621756	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT621755	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT621754	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT621753	hsa-miR-526a	HITS-CLIP	23824327
MIRT621752	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT621751	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT621750	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT621749	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT621748	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT621770	hsa-miR-5700	HITS-CLIP	23824327
MIRT621769	hsa-miR-2278	HITS-CLIP	23824327
MIRT621768	hsa-miR-586	HITS-CLIP	23824327
MIRT621767	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT621766	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT621765	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT621764	hsa-miR-520g-5p	HITS-CLIP	23824327
MIRT621763	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT621762	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT621761	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT621760	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT621759	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT621758	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT621757	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT621756	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT621755	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT621754	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT621753	hsa-miR-526a	HITS-CLIP	23824327
MIRT621752	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT621751	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT621750	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT621749	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT621748	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT621770	hsa-miR-5700	HITS-CLIP	23824327
MIRT621769	hsa-miR-2278	HITS-CLIP	23824327
MIRT621768	hsa-miR-586	HITS-CLIP	23824327
MIRT621767	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT621766	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT621765	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT621764	hsa-miR-520g-5p	HITS-CLIP	23824327
MIRT621763	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT621762	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT621761	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT621760	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT621759	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT621758	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT621757	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT621756	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT621755	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT621754	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT621753	hsa-miR-526a	HITS-CLIP	23824327
MIRT621752	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT621751	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT621750	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT621749	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT621748	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT553493	hsa-miR-23c	PAR-CLIP	21572407
MIRT553492	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT553491	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT553490	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT553489	hsa-miR-6507-5p	PAR-CLIP	21572407
MIRT553488	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT553487	hsa-miR-3688-3p	PAR-CLIP	21572407
MIRT553486	hsa-miR-5093	PAR-CLIP	21572407
MIRT553485	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT553484	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT553483	hsa-miR-3658	PAR-CLIP	21572407
MIRT553482	hsa-miR-5096	PAR-CLIP	21572407
MIRT553481	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT448422	hsa-miR-5692a	PAR-CLIP	22100165
MIRT450585	hsa-miR-141-5p	PAR-CLIP	22100165
MIRT448421	hsa-miR-412-3p	PAR-CLIP	22100165
MIRT448420	hsa-miR-6754-3p	PAR-CLIP	22100165
MIRT448419	hsa-miR-6837-3p	PAR-CLIP	22100165
MIRT448406	hsa-miR-4635	PAR-CLIP	22100165
MIRT448418	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448417	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448416	hsa-miR-573	PAR-CLIP	22100165
MIRT448422	hsa-miR-5692a	PAR-CLIP	22100165
MIRT448421	hsa-miR-412-3p	PAR-CLIP	22100165
MIRT448420	hsa-miR-6754-3p	PAR-CLIP	22100165
MIRT448419	hsa-miR-6837-3p	PAR-CLIP	22100165
MIRT448418	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448417	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448416	hsa-miR-573	PAR-CLIP	22100165
MIRT448415	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT448414	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT448413	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT448412	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT448411	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT448410	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT448409	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT448408	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT448407	hsa-miR-4729	PAR-CLIP	22100165
MIRT448406	hsa-miR-4635	PAR-CLIP	22100165
MIRT448405	hsa-miR-3185	PAR-CLIP	22100165
MIRT448403	hsa-miR-4709-3p	PAR-CLIP	22100165
MIRT439414	hsa-miR-374a-5p	HITS-CLIP	22473208
MIRT726266	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT726265	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT439414	hsa-miR-374a-5p	HITS-CLIP	22473208
MIRT006472	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	27637078
MIRT006472	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	27637078
MIRT726265	hsa-miR-19b-3p	Luciferase reporter assay, qRT-PCR, Western blot	27919278
MIRT726265	hsa-miR-19b-3p	Luciferase reporter assay, qRT-PCR, Western blot	27919278
MIRT726266	hsa-miR-19a-3p	Luciferase reporter assay, qRT-PCR, Western blot	26367773
MIRT006471	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	26758190
MIRT006471	hsa-miR-125a-5p	Luciferase reporter assay, qRT-PCR, Western blot	26758190
MIRT006472	hsa-miR-125b-5p	qRT-PCR	32039213
MIRT553490	hsa-miR-23a-3p	Luciferase reporter assay, Western blotting, RNA-seq, qRT-PCR	34201504
MIRT736719	hsa-miR-605-5p	Luciferase reporter assay, Western blotting, qRT-PCR	31452243
MIRT621770	hsa-miR-5700	HITS-CLIP	23824327
MIRT621769	hsa-miR-2278	HITS-CLIP	23824327
MIRT621768	hsa-miR-586	HITS-CLIP	23824327
MIRT621767	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT621766	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT621765	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT621764	hsa-miR-520g-5p	HITS-CLIP	23824327
MIRT621763	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT621762	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT621761	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT621760	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT621759	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT621758	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT621757	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT621756	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT621755	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT621754	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT621753	hsa-miR-526a	HITS-CLIP	23824327
MIRT621752	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT621751	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT621750	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT621749	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT621748	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT621770	hsa-miR-5700	HITS-CLIP	23824327
MIRT621769	hsa-miR-2278	HITS-CLIP	23824327
MIRT621768	hsa-miR-586	HITS-CLIP	23824327
MIRT621767	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT621766	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT621765	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT621764	hsa-miR-520g-5p	HITS-CLIP	23824327
MIRT621763	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT621762	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT621761	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT621760	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT621759	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT621758	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT621757	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT621756	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT621755	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT621754	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT621753	hsa-miR-526a	HITS-CLIP	23824327
MIRT621752	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT621751	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT621750	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT621749	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT621748	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT621770	hsa-miR-5700	HITS-CLIP	23824327
MIRT621769	hsa-miR-2278	HITS-CLIP	23824327
MIRT621768	hsa-miR-586	HITS-CLIP	23824327
MIRT621767	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT621766	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT621765	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT621764	hsa-miR-520g-5p	HITS-CLIP	23824327
MIRT621763	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT621762	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT621761	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT621760	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT621759	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT621758	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT621757	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT621756	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT621755	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT621754	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT621753	hsa-miR-526a	HITS-CLIP	23824327
MIRT621752	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT621751	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT621750	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT621749	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT621748	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT553493	hsa-miR-23c	PAR-CLIP	21572407
MIRT553492	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT553491	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT553490	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT553489	hsa-miR-6507-5p	PAR-CLIP	21572407
MIRT553488	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT553487	hsa-miR-3688-3p	PAR-CLIP	21572407
MIRT553486	hsa-miR-5093	PAR-CLIP	21572407
MIRT553485	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT553484	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT553483	hsa-miR-3658	PAR-CLIP	21572407
MIRT553482	hsa-miR-5096	PAR-CLIP	21572407
MIRT553481	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT448422	hsa-miR-5692a	PAR-CLIP	22100165
MIRT450585	hsa-miR-141-5p	PAR-CLIP	22100165
MIRT448421	hsa-miR-412-3p	PAR-CLIP	22100165
MIRT448420	hsa-miR-6754-3p	PAR-CLIP	22100165
MIRT448419	hsa-miR-6837-3p	PAR-CLIP	22100165
MIRT448406	hsa-miR-4635	PAR-CLIP	22100165
MIRT448418	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448417	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448416	hsa-miR-573	PAR-CLIP	22100165
MIRT448422	hsa-miR-5692a	PAR-CLIP	22100165
MIRT448421	hsa-miR-412-3p	PAR-CLIP	22100165
MIRT448420	hsa-miR-6754-3p	PAR-CLIP	22100165
MIRT448419	hsa-miR-6837-3p	PAR-CLIP	22100165
MIRT448418	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448417	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448416	hsa-miR-573	PAR-CLIP	22100165
MIRT448415	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT448414	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT448413	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT448412	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT448411	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT448410	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT448409	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT448408	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT448407	hsa-miR-4729	PAR-CLIP	22100165
MIRT448406	hsa-miR-4635	PAR-CLIP	22100165
MIRT448405	hsa-miR-3185	PAR-CLIP	22100165
MIRT448403	hsa-miR-4709-3p	PAR-CLIP	22100165
MIRT1442249	hsa-miR-1208	CLIP-seq
MIRT1442250	hsa-miR-1238	CLIP-seq
MIRT1442251	hsa-miR-1324	CLIP-seq
MIRT1442252	hsa-miR-186	CLIP-seq
MIRT1442253	hsa-miR-193a-3p	CLIP-seq
MIRT1442254	hsa-miR-193b	CLIP-seq
MIRT1442255	hsa-miR-1976	CLIP-seq
MIRT1442256	hsa-miR-3065-5p	CLIP-seq
MIRT1442257	hsa-miR-3119	CLIP-seq
MIRT1442258	hsa-miR-3124-3p	CLIP-seq
MIRT1442259	hsa-miR-3140-3p	CLIP-seq
MIRT1442260	hsa-miR-3160-5p	CLIP-seq
MIRT1442261	hsa-miR-3183	CLIP-seq
MIRT1442262	hsa-miR-3184	CLIP-seq
MIRT1442263	hsa-miR-370	CLIP-seq
MIRT1442264	hsa-miR-3914	CLIP-seq
MIRT1442265	hsa-miR-409-5p	CLIP-seq
MIRT1442266	hsa-miR-423-5p	CLIP-seq
MIRT1442267	hsa-miR-4257	CLIP-seq
MIRT1442268	hsa-miR-4519	CLIP-seq
MIRT1442269	hsa-miR-4684-3p	CLIP-seq
MIRT1442270	hsa-miR-4723-3p	CLIP-seq
MIRT1442271	hsa-miR-4736	CLIP-seq
MIRT1442272	hsa-miR-4797-5p	CLIP-seq
MIRT1442273	hsa-miR-491-3p	CLIP-seq
MIRT1442274	hsa-miR-563	CLIP-seq
MIRT1442275	hsa-miR-626	CLIP-seq
MIRT1442276	hsa-miR-767-3p	CLIP-seq
MIRT1442277	hsa-miR-873	CLIP-seq
MIRT1442278	hsa-miR-885-3p	CLIP-seq
MIRT1442279	hsa-miR-892b	CLIP-seq
MIRT1555049	hsa-miR-18a	CLIP-seq
MIRT1555050	hsa-miR-18b	CLIP-seq
MIRT1555051	hsa-miR-4735-3p	CLIP-seq
MIRT1555052	hsa-miR-4735-5p	CLIP-seq
MIRT1555053	hsa-miR-4775	CLIP-seq
MIRT1555054	hsa-miR-576-5p	CLIP-seq
MIRT1555055	hsa-miR-590-3p	CLIP-seq
MIRT2132408	hsa-miR-1237	CLIP-seq
MIRT2132409	hsa-miR-1248	CLIP-seq
MIRT2132410	hsa-miR-1343	CLIP-seq
MIRT1555049	hsa-miR-18a	CLIP-seq
MIRT1555050	hsa-miR-18b	CLIP-seq
MIRT2132411	hsa-miR-3074-5p	CLIP-seq
MIRT1442258	hsa-miR-3124-3p	CLIP-seq
MIRT2132412	hsa-miR-3150a-3p	CLIP-seq
MIRT2132413	hsa-miR-3175	CLIP-seq
MIRT2132414	hsa-miR-376c	CLIP-seq
MIRT2132415	hsa-miR-4667-5p	CLIP-seq
MIRT2132416	hsa-miR-4700-5p	CLIP-seq
MIRT1555051	hsa-miR-4735-3p	CLIP-seq
MIRT1555052	hsa-miR-4735-5p	CLIP-seq
MIRT1555053	hsa-miR-4775	CLIP-seq
MIRT2132417	hsa-miR-548aa	CLIP-seq
MIRT2132418	hsa-miR-556-3p	CLIP-seq
MIRT1555054	hsa-miR-576-5p	CLIP-seq
MIRT1555055	hsa-miR-590-3p	CLIP-seq
MIRT2132419	hsa-miR-939	CLIP-seq
MIRT2353440	hsa-miR-128	CLIP-seq
MIRT2353441	hsa-miR-27a	CLIP-seq
MIRT2353442	hsa-miR-27b	CLIP-seq
MIRT1442267	hsa-miR-4257	CLIP-seq
MIRT2353443	hsa-miR-455-3p	CLIP-seq
MIRT1442272	hsa-miR-4797-5p	CLIP-seq
MIRT2396097	hsa-miR-4446-5p	CLIP-seq
MIRT2396098	hsa-miR-4755-5p	CLIP-seq
MIRT2441399	hsa-miR-1202	CLIP-seq
MIRT2441400	hsa-miR-1265	CLIP-seq
MIRT2441401	hsa-miR-1266	CLIP-seq
MIRT2441402	hsa-miR-1286	CLIP-seq
MIRT2441403	hsa-miR-141	CLIP-seq
MIRT2441404	hsa-miR-188-5p	CLIP-seq
MIRT2441405	hsa-miR-200a	CLIP-seq
MIRT2441406	hsa-miR-2117	CLIP-seq
MIRT2441407	hsa-miR-2277-3p	CLIP-seq
MIRT2441408	hsa-miR-330-3p	CLIP-seq
MIRT2441409	hsa-miR-3664-3p	CLIP-seq
MIRT2441410	hsa-miR-3688-5p	CLIP-seq
MIRT2441411	hsa-miR-3689d	CLIP-seq
MIRT2441412	hsa-miR-3913-3p	CLIP-seq
MIRT2441413	hsa-miR-3972	CLIP-seq
MIRT2441414	hsa-miR-4273	CLIP-seq
MIRT2441415	hsa-miR-4286	CLIP-seq
MIRT2441416	hsa-miR-4318	CLIP-seq
MIRT2441417	hsa-miR-4433	CLIP-seq
MIRT2396097	hsa-miR-4446-5p	CLIP-seq
MIRT2441418	hsa-miR-4459	CLIP-seq
MIRT2441419	hsa-miR-4518	CLIP-seq
MIRT2441420	hsa-miR-4722-5p	CLIP-seq
MIRT2441421	hsa-miR-4753-5p	CLIP-seq
MIRT2441422	hsa-miR-4758-3p	CLIP-seq
MIRT2441423	hsa-miR-4768-3p	CLIP-seq
MIRT2441424	hsa-miR-4768-5p	CLIP-seq
MIRT2441425	hsa-miR-4780	CLIP-seq
MIRT2441426	hsa-miR-489	CLIP-seq
MIRT2441427	hsa-miR-623	CLIP-seq
MIRT2441428	hsa-miR-888	CLIP-seq
MIRT2441429	hsa-miR-935	CLIP-seq
MIRT2647426	hsa-let-7a	CLIP-seq
MIRT2647427	hsa-let-7b	CLIP-seq
MIRT2647428	hsa-let-7c	CLIP-seq
MIRT2647429	hsa-let-7d	CLIP-seq
MIRT2647430	hsa-let-7e	CLIP-seq
MIRT2647431	hsa-let-7f	CLIP-seq
MIRT2647432	hsa-let-7g	CLIP-seq
MIRT2647433	hsa-let-7i	CLIP-seq
MIRT2441399	hsa-miR-1202	CLIP-seq
MIRT2647434	hsa-miR-1207-3p	CLIP-seq
MIRT2647435	hsa-miR-1256	CLIP-seq
MIRT2441400	hsa-miR-1265	CLIP-seq
MIRT2441401	hsa-miR-1266	CLIP-seq
MIRT2441403	hsa-miR-141	CLIP-seq
MIRT2441404	hsa-miR-188-5p	CLIP-seq
MIRT2441405	hsa-miR-200a	CLIP-seq
MIRT2647436	hsa-miR-204	CLIP-seq
MIRT2647437	hsa-miR-211	CLIP-seq
MIRT2647438	hsa-miR-2110	CLIP-seq
MIRT2441406	hsa-miR-2117	CLIP-seq
MIRT2647439	hsa-miR-2355-5p	CLIP-seq
MIRT2647440	hsa-miR-3160-3p	CLIP-seq
MIRT1442260	hsa-miR-3160-5p	CLIP-seq
MIRT2647441	hsa-miR-3173-3p	CLIP-seq
MIRT2647442	hsa-miR-326	CLIP-seq
MIRT2441408	hsa-miR-330-3p	CLIP-seq
MIRT2647443	hsa-miR-330-5p	CLIP-seq
MIRT2647444	hsa-miR-3647-5p	CLIP-seq
MIRT2441409	hsa-miR-3664-3p	CLIP-seq
MIRT2647445	hsa-miR-3675-3p	CLIP-seq
MIRT2441410	hsa-miR-3688-5p	CLIP-seq
MIRT2647446	hsa-miR-3714	CLIP-seq
MIRT2441412	hsa-miR-3913-3p	CLIP-seq
MIRT2647447	hsa-miR-3941	CLIP-seq
MIRT2441413	hsa-miR-3972	CLIP-seq
MIRT2647448	hsa-miR-412	CLIP-seq
MIRT2647449	hsa-miR-4263	CLIP-seq
MIRT2647450	hsa-miR-4271	CLIP-seq
MIRT2441414	hsa-miR-4273	CLIP-seq
MIRT2647451	hsa-miR-4287	CLIP-seq
MIRT2441416	hsa-miR-4318	CLIP-seq
MIRT2441417	hsa-miR-4433	CLIP-seq
MIRT2396097	hsa-miR-4446-5p	CLIP-seq
MIRT2647452	hsa-miR-4458	CLIP-seq
MIRT2441418	hsa-miR-4459	CLIP-seq
MIRT2647453	hsa-miR-4500	CLIP-seq
MIRT2441419	hsa-miR-4518	CLIP-seq
MIRT1442268	hsa-miR-4519	CLIP-seq
MIRT2647454	hsa-miR-4521	CLIP-seq
MIRT2647455	hsa-miR-466	CLIP-seq
MIRT2132415	hsa-miR-4667-5p	CLIP-seq
MIRT2647456	hsa-miR-4668-5p	CLIP-seq
MIRT2647457	hsa-miR-4672	CLIP-seq
MIRT2647458	hsa-miR-4685-3p	CLIP-seq
MIRT2647459	hsa-miR-4698	CLIP-seq
MIRT2132416	hsa-miR-4700-5p	CLIP-seq
MIRT2647460	hsa-miR-4717-5p	CLIP-seq
MIRT2647461	hsa-miR-4725-3p	CLIP-seq
MIRT2647462	hsa-miR-4731-3p	CLIP-seq
MIRT2441421	hsa-miR-4753-5p	CLIP-seq
MIRT2647463	hsa-miR-4759	CLIP-seq
MIRT2441423	hsa-miR-4768-3p	CLIP-seq
MIRT2441424	hsa-miR-4768-5p	CLIP-seq
MIRT2441425	hsa-miR-4780	CLIP-seq
MIRT2647464	hsa-miR-4789-5p	CLIP-seq
MIRT2647465	hsa-miR-4801	CLIP-seq
MIRT2441426	hsa-miR-489	CLIP-seq
MIRT1442273	hsa-miR-491-3p	CLIP-seq
MIRT2647466	hsa-miR-515-5p	CLIP-seq
MIRT2647467	hsa-miR-548an	CLIP-seq
MIRT1442274	hsa-miR-563	CLIP-seq
MIRT1555054	hsa-miR-576-5p	CLIP-seq
MIRT2441427	hsa-miR-623	CLIP-seq
MIRT2647468	hsa-miR-637	CLIP-seq
MIRT1442278	hsa-miR-885-3p	CLIP-seq
MIRT2441428	hsa-miR-888	CLIP-seq
MIRT2441429	hsa-miR-935	CLIP-seq
MIRT2647469	hsa-miR-98	CLIP-seq
MIRT2441399	hsa-miR-1202	CLIP-seq
MIRT2647435	hsa-miR-1256	CLIP-seq
MIRT2441400	hsa-miR-1265	CLIP-seq
MIRT2441401	hsa-miR-1266	CLIP-seq
MIRT2693653	hsa-miR-1292	CLIP-seq
MIRT2441403	hsa-miR-141	CLIP-seq
MIRT2441404	hsa-miR-188-5p	CLIP-seq
MIRT2441405	hsa-miR-200a	CLIP-seq
MIRT2647438	hsa-miR-2110	CLIP-seq
MIRT2441406	hsa-miR-2117	CLIP-seq
MIRT2647439	hsa-miR-2355-5p	CLIP-seq
MIRT2647440	hsa-miR-3160-3p	CLIP-seq
MIRT1442260	hsa-miR-3160-5p	CLIP-seq
MIRT2647442	hsa-miR-326	CLIP-seq
MIRT2441408	hsa-miR-330-3p	CLIP-seq
MIRT2647443	hsa-miR-330-5p	CLIP-seq
MIRT2441409	hsa-miR-3664-3p	CLIP-seq
MIRT2647445	hsa-miR-3675-3p	CLIP-seq
MIRT2441410	hsa-miR-3688-5p	CLIP-seq
MIRT2441412	hsa-miR-3913-3p	CLIP-seq
MIRT2441413	hsa-miR-3972	CLIP-seq
MIRT2647449	hsa-miR-4263	CLIP-seq
MIRT2647450	hsa-miR-4271	CLIP-seq
MIRT2441414	hsa-miR-4273	CLIP-seq
MIRT2441416	hsa-miR-4318	CLIP-seq
MIRT2441417	hsa-miR-4433	CLIP-seq
MIRT2396097	hsa-miR-4446-5p	CLIP-seq
MIRT2441418	hsa-miR-4459	CLIP-seq
MIRT2693654	hsa-miR-4471	CLIP-seq
MIRT2441419	hsa-miR-4518	CLIP-seq
MIRT2647454	hsa-miR-4521	CLIP-seq
MIRT2693655	hsa-miR-4646-5p	CLIP-seq
MIRT2132415	hsa-miR-4667-5p	CLIP-seq
MIRT2647456	hsa-miR-4668-5p	CLIP-seq
MIRT2647459	hsa-miR-4698	CLIP-seq
MIRT2132416	hsa-miR-4700-5p	CLIP-seq
MIRT2647460	hsa-miR-4717-5p	CLIP-seq
MIRT2647461	hsa-miR-4725-3p	CLIP-seq
MIRT2441421	hsa-miR-4753-5p	CLIP-seq
MIRT2441423	hsa-miR-4768-3p	CLIP-seq
MIRT2441424	hsa-miR-4768-5p	CLIP-seq
MIRT2441425	hsa-miR-4780	CLIP-seq
MIRT2441426	hsa-miR-489	CLIP-seq
MIRT1555054	hsa-miR-576-5p	CLIP-seq
MIRT2441427	hsa-miR-623	CLIP-seq
MIRT2647468	hsa-miR-637	CLIP-seq
MIRT1442278	hsa-miR-885-3p	CLIP-seq
MIRT2441428	hsa-miR-888	CLIP-seq
MIRT2441429	hsa-miR-935	CLIP-seq

Transcription factors

Show/Hide all(6)

Transcription factor	Regulation	Reference
NFKB1	Activation	11880364;19343319
NFKB1	Unknown	10807933
PML	Repression	12080044
REL	Activation	11880364
RELA	Activation	11880364;19343319
RELA	Unknown	10807933

Show/Hide all(78)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001922	Process	B-1 B cell homeostasis	ISS
GO:0002020	Function	Protease binding	IPI	18223652
GO:0002237	Process	Response to molecule of bacterial origin	IDA	19912257
GO:0002634	Process	Regulation of germinal center formation	ISS
GO:0002677	Process	Negative regulation of chronic inflammatory response	IEA
GO:0003677	Function	DNA binding	IEA
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	15258597
GO:0004843	Function	Thiol-dependent ubiquitin-specific protease activity	IBA	21873635
GO:0004843	Function	Thiol-dependent ubiquitin-specific protease activity	IDA	15258597, 23827681
GO:0004843	Function	Thiol-dependent ubiquitin-specific protease activity	IMP	15258597
GO:0004843	Function	Thiol-dependent ubiquitin-specific protease activity	TAS	20392859
GO:0005515	Function	Protein binding	IPI	9299557, 11463333, 15142865, 15169888, 15231748, 15474016, 19060883, 19131965, 20392859, 21988832, 23032186, 25416956, 30561431, 31515488, 32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	11463333
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005764	Component	Lysosome	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0006954	Process	Inflammatory response	IEA
GO:0007010	Process	Cytoskeleton organization	IBA	21873635
GO:0008022	Function	Protein C-terminus binding	IEA
GO:0008234	Function	Cysteine-type peptidase activity	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010803	Process	Regulation of tumor necrosis factor-mediated signaling pathway	TAS
GO:0016477	Process	Cell migration	IBA	21873635
GO:0016579	Process	Protein deubiquitination	TAS	20392859
GO:0018215	Process	Protein phosphopantetheinylation	IEA
GO:0019900	Function	Kinase binding	IEA
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IBA	21873635
GO:0031397	Process	Negative regulation of protein ubiquitination	IDA	20392859
GO:0032088	Process	Negative regulation of NF-kappaB transcription factor activity	IDA	18223652
GO:0032480	Process	Negative regulation of type I interferon production	TAS
GO:0032495	Process	Response to muramyl dipeptide	IEA
GO:0032691	Process	Negative regulation of interleukin-1 beta production	IMP	28094437
GO:0032703	Process	Negative regulation of interleukin-2 production	IMP	18223652
GO:0032715	Process	Negative regulation of interleukin-6 production	ISS
GO:0032720	Process	Negative regulation of tumor necrosis factor production	ISS
GO:0034136	Process	Negative regulation of toll-like receptor 2 signaling pathway	NAS	15142865
GO:0034140	Process	Negative regulation of toll-like receptor 3 signaling pathway	IDA	15474016
GO:0034144	Process	Negative regulation of toll-like receptor 4 signaling pathway	NAS	15142865
GO:0034148	Process	Negative regulation of toll-like receptor 5 signaling pathway	IEA
GO:0035523	Process	Protein K29-linked deubiquitination	IBA	21873635
GO:0035871	Process	Protein K11-linked deubiquitination	IDA	23827681
GO:0042802	Function	Identical protein binding	IPI	25416956, 25502805, 30561431, 31515488, 32296183
GO:0043124	Process	Negative regulation of I-kappaB kinase/NF-kappaB signaling	IDA	11463333, 15258597, 21127049
GO:0043130	Function	Ubiquitin binding	IPI	19285159
GO:0043621	Function	Protein self-association	IDA	8797804, 15474016
GO:0045732	Process	Positive regulation of protein catabolic process	IDA	21127049
GO:0045736	Process	Negative regulation of cyclin-dependent protein serine/threonine kinase activity	IEA
GO:0045779	Process	Negative regulation of bone resorption	NAS	21127049
GO:0045824	Process	Negative regulation of innate immune response	ISS
GO:0048662	Process	Negative regulation of smooth muscle cell proliferation	IDA	16816117
GO:0050691	Process	Regulation of defense response to virus by host	NAS	15142865
GO:0050728	Process	Negative regulation of inflammatory response	ISS
GO:0050869	Process	Negative regulation of B cell activation	ISS
GO:0061043	Process	Regulation of vascular wound healing	NAS	16816117
GO:0061578	Function	Lys63-specific deubiquitinase activity	EXP	14748687
GO:0061578	Function	Lys63-specific deubiquitinase activity	TAS
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0070301	Process	Cellular response to hydrogen peroxide	ISS
GO:0070423	Process	Nucleotide-binding oligomerization domain containing signaling pathway	TAS
GO:0070429	Process	Negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	IEA
GO:0070433	Process	Negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	IEA
GO:0070530	Function	K63-linked polyubiquitin modification-dependent protein binding	IBA	21873635
GO:0070536	Process	Protein K63-linked deubiquitination	IDA	15258597
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	15258597
GO:0071108	Process	Protein K48-linked deubiquitination	IDA	23827681
GO:0071222	Process	Cellular response to lipopolysaccharide	IDA	19912257, 21127049, 21220427
GO:0071947	Process	Protein deubiquitination involved in ubiquitin-dependent protein catabolic process	IBA	21873635
GO:0072573	Process	Tolerance induction to lipopolysaccharide	IMP	21220427
GO:0072666	Process	Establishment of protein localization to vacuole	IEA
GO:0090291	Process	Negative regulation of osteoclast proliferation	NAS	21127049
GO:1902042	Process	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	IDA	12167698
GO:1903364	Process	Positive regulation of cellular protein catabolic process	IEA
GO:1990168	Process	Protein K33-linked deubiquitination	IBA	21873635
GO:2000347	Process	Positive regulation of hepatocyte proliferation	IEA
GO:2000349	Process	Negative regulation of CD40 signaling pathway	IMP	12885753
GO:2000352	Process	Negative regulation of endothelial cell apoptotic process	IDA	12885753

MIM	HGNC	e!Ensembl
191163	11896	ENSG00000118503

Protein

UniProt ID

P21580

Protein name

Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]

Protein function

Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through

PDB

2EQE , 2EQF , 2EQG , 2VFJ , 3DKB , 3OJ3 , 3OJ4 , 3VUW , 3VUX , 3VUY , 3ZJD , 3ZJE , 3ZJF , 3ZJG , 5LRX , 5V3B , 5V3P

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02338	OTU	98 → 257	OTU-like cysteine protease	Family
PF01754	zf-A20	385 → 409	A20-like zinc finger	Family
PF01754	zf-A20	476 → 500	A20-like zinc finger	Family
PF01754	zf-A20	655 → 678	A20-like zinc finger	Family
PF01754	zf-A20	760 → 784	A20-like zinc finger	Family

Sequence

MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
ECFQFKQMYG

Sequence length

790

Interactions

View interactions

	KEGG		Reactome
	NF-kappa B signaling pathway Necroptosis NOD-like receptor signaling pathway IL-17 signaling pathway TNF signaling pathway Measles Epstein-Barr virus infection		NOD1/2 Signaling Pathway TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Ovarian tumor domain proteases Negative regulators of DDX58/IFIH1 signaling

Associated diseases

Show/Hide Causal Diseases (8)

Causal
Disease name	Disease term	dbSNP ID	References
Autoimmune diseases	Autoimmune Diseases	rs41285370, rs869025224	24453940
Autoimmune lymphoproliferative disorder	Autoimmune Lymphoproliferative Syndrome	rs17860424, rs112445441, rs121913529, rs121434596, rs80358236, rs606231361, rs606231362, rs121913076, rs606231363, rs121913077, rs28929498, rs121913080, rs267607122, rs606231364, rs606231365, rs121913085, rs606231366, rs121913086, rs121913237, rs121913535, rs398122958, rs606231296, rs886039524, rs121913527, rs1554851718, rs1295207359, rs1564699214, rs1564686301, rs1564696849, rs1564691414, rs747862347, rs1589482683, rs1589488463, rs1589488640, rs1589488494, rs1589465172, rs1589478691, rs1589485636, rs778993919, rs1842954041, rs1848315820, rs1207744817, rs1848558128, rs1848671126, rs1848675068, rs1848019699	29317407
Autoinflammatory disease	Autoinflammatory disorder, AUTOINFLAMMATORY SYNDROME, FAMILIAL, BEHCET-LIKE, Hereditary Autoinflammatory Diseases	rs777759523, rs121434352, rs28940578, rs28940580, rs121908146, rs121908148, rs121908150, rs80338807, rs121908679, rs104895319, rs104894176, rs28933973, rs28933376, rs137854447, rs61736587, rs148755083, rs104895093, rs104895311, rs104895364, rs104895352, rs104895271, rs104895238, rs151344629, rs180177431, rs376785840, rs587777241, rs77563738, rs202134424, rs864321625, rs864321682, rs864321626, rs864321684, rs864321685, rs869312838, rs869312953, rs766657895, rs140148806, rs753966933, rs764196809, rs200956636, rs147035858, rs1274685768, rs1600700389, rs1776278098, rs754904956, rs1760720617, rs1760720924	29317407, 26642243, 29317407, 27175295, 26642243
Lymphoma	Lymphoma, Lymphoma, Follicular, Lymphoma, Large-Cell, Follicular, Lymphoma, Mixed-Cell, Follicular, Lymphoma, Small Cleaved-Cell, Follicular, Lymphoma, T-Cell, Cutaneous, Lymphoma, Follicular, Grade 1, Lymphoma, Follicular, Grade 3, Lymphoma, Follicular, Grade 2	rs11540652, rs1592119138, rs1592123162, rs1599367044	24362818, 26192916
Multiple sclerosis	Multiple Sclerosis, Multiple Sclerosis, Acute Fulminating	rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544	24076602, 22190364, 24076602
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	26626624, 25903422, 19169254, 23143594, 20953190, 26974007, 25574825, 20953187
Rheumatoid arthritis	Rheumatoid Arthritis	rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212	20453842, 22446963, 30224649, 23143596, 21841782, 18794853
Systemic lupus erythematosus	Systemic lupus erythematosus	rs77571059, rs10954213, rs2070197, rs72556554, rs3219018, rs121912990, rs1575496354, rs7574865, rs1307379746, rs758750492, rs1575497576

Show/Hide Unknown Diseases (18)

Unknown
Disease name	Disease term	dbSNP ID	References
Ankylosing spondylitis	Ankylosing spondylitis		26974007
B-cell lymphoma	B-Cell Lymphomas
Cholangitis	Cholangitis, Sclerosing		26974007
Crohn disease	Crohn Disease	rs2066847, rs2066844, rs886052047, rs5743265, rs111608429, rs104895438	26974007
Eczema	Eczema		30595370
Genital ulcers	Genital ulcers
Granulomatous slack skin	Granulomatous Slack Skin		26192916
Hereditary pediatric behcet-like disease	Hereditary pediatric Beh�et-like disease
Hodgkin disease	Hodgkin Disease
Lupus erythematosus	Lupus Erythematosus, Systemic		28714469, 19838193, 22654485, 19165918, 19838195, 24091983, 26663301, 23273568, 24039598, 20617138, 27399966, 21336280, 23943494, 19165919
Malignant neoplasm	Malignant Neoplasms		29299148
Nonbacterial verrucal endocardiosis	Libman-Sacks Disease		21336280, 19165918, 19165919, 19838193
Oral ulcer	Oral Ulcer
Palmoplantar pustules	Pustulosis of Palms and Soles		19169254, 20953190
Psoriasis vulgaris	Psoriasis vulgaris		26626624
Scleroderma	Systemic Scleroderma		28314753
Sjogren`s syndrome	Sicca Syndrome, Sjogren`s Syndrome		24097066, 24097067, 24097067, 24097066
Ulcerative colitis	Ulcerative Colitis		26974007

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