GediPNet logo

STX3 (syntaxin 3)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6809
Gene nameGene Name - the full gene name approved by the HGNC.
Syntaxin 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
STX3
SynonymsGene synonyms aliases
DIAR12, MVID2, RDMVID, STX3A
ChromosomeChromosome number
11
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.1
SummarySummary of gene provided in NCBI Entrez Gene.
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle f
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019943 hsa-miR-375 Microarray 20215506
MIRT049197 hsa-miR-92a-3p CLASH 23622248
MIRT1400841 hsa-let-7a CLIP-seq
MIRT1400842 hsa-let-7b CLIP-seq
MIRT1400843 hsa-let-7c CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000149 Function SNARE binding IBA 21873635
GO:0005484 Function SNAP receptor activity IBA 21873635
GO:0005515 Function Protein binding IPI 18588921, 25416956, 29892012, 31515488, 32296183
GO:0005773 Component Vacuole TAS 16339081
GO:0005886 Component Plasma membrane IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q13277
Protein name Syntaxin-3
Protein function Potentially involved in docking of synaptic vesicles at presynaptic active zones. Apical receptor involved in membrane fusion of apical vesicles. ; [Isoform B]: Essential for survival of retinal photorecee
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00804 Syntaxin
32 226
Syntaxin
Domain
PF05739 SNARE
227 279
SNARE domain
Family
Sequence
Sequence length 289
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  SNARE interactions in vesicular transport
Synaptic vesicle cycle
  Other interleukin signaling
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Developmental delay Global developmental delay rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291, rs886041382, rs1057518991, rs1057518699, rs753254213, rs748294403, rs762552974, rs1135401795, rs1553121073, rs1553122926, rs1364690005, rs1554086554, rs1554210415, rs1554168326, rs1554776342, rs1553873247, rs1567860112, rs779009256, rs1557447255, rs1564568350, rs780011005, rs1597464953, rs1200336864, rs1569513017, rs1587459606, rs1570332505, rs748888652, rs1575155995, rs2087029320, rs1589669105, rs1601769604, rs1184981709, rs749201074
Unknown
Disease name Disease term dbSNP ID References
Microvillus inclusion disease Microvillus inclusion disease 29282386, 24726755
Nephrocalcinosis Nephrocalcinosis

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412