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SSX1 (SSX family member 1)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6756
Gene nameGene Name - the full gene name approved by the HGNC.
SSX family member 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SSX1
SynonymsGene synonyms aliases
CT5.1, SPGFX5, SSRC
ChromosomeChromosome number
X
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xp11.23
SummarySummary of gene provided in NCBI Entrez Gene.
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune respons
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT025895 hsa-miR-7-5p Microarray 17612493
MIRT1392930 hsa-miR-134 CLIP-seq
MIRT1392931 hsa-miR-223 CLIP-seq
MIRT1392932 hsa-miR-3118 CLIP-seq
MIRT1392933 hsa-miR-3136-5p CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 10072425
GO:0003714 Function Transcription corepressor activity IMP 10072425
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005634 Component Nucleus IBA 21873635
GO:0005634 Component Nucleus IDA 10072425
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q16384
Protein name Protein SSX1 (Cancer/testis antigen 5.1) (CT5.1) (Synovial sarcoma, X breakpoint 1)
Protein function Could act as a modulator of transcription (PubMed:7539744). Plays a role in spermatogenesis (PubMed:36796361).
PDB 8HR1
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB
22 → 62
KRAB box
 Family
PF09514 SSXRD
157 → 187
SSXRD motif
 Motif
Sequence 
MNGDDTFAKRPRDDAKASEKRSKAFDDIATYFSKKEWKKMKYSEKISYVYMKRNYKAMTK
LGFKVTLPPFMCNKQATDFQGNDFDNDHNRRIQVEHPQMTFGRLHRIIPKIMPKKPAEDE
NDSKGVSEASGPQNDGKQLHPPGKANISEKINKRSGPKRGKHAWTHRLRERKQLVIYEEI
SDPEEDDE
Sequence length 188
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
  Transcriptional misregulation in cancer  
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Liver carcinoma Liver carcinoma 28284560
Synovial sarcoma synovial sarcoma 9428816, 27572315

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