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SRMS (src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites)
Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6725
Gene nameGene Name - the full gene name approved by the HGNC.
Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SRMS
SynonymsGene synonyms aliases
C20orf148, PTK70, SRM, dJ697K14.1
ChromosomeChromosome number
20
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
20q13.33
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0004713 Function Protein tyrosine kinase activity EXP 25897081
GO:0004713 Function Protein tyrosine kinase activity IBA 21873635
GO:0004713 Function Protein tyrosine kinase activity IDA 23822091, 29496907
GO:0004715 Function Non-membrane spanning protein tyrosine kinase activity IBA 21873635
GO:0005102 Function Signaling receptor binding IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9H3Y6
Protein name Tyrosine-protein kinase Srms (EC 2.7.10.2)
Protein function Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues (PubMed:23822091). Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907). Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00017 SH2
120 → 197
SH2 domain
 Domain
PF07714 PK_Tyr_Ser-Thr
230 → 480
Protein tyrosine and serine/threonine kinase
 Domain
Sequence
Sequence length 488
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
 
Reactome
    PTK6 Down-Regulation
Associated diseases
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Liver neoplasms Liver neoplasms 19233941
Liver cancer Malignant neoplasm of liver 19233941

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