Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6542 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Solute carrier family 7 member 2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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SLC7A2 |
SynonymsGene synonyms aliases
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ATRC2, CAT-2A, CAT-2B, CAT2, HCAT2, SLC7A2A, SLC7A2B |
ChromosomeChromosome number
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8 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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8p22 |
SummarySummary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
P52569 |
Protein name |
Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) |
Protein function |
Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:28684763, PubM |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF13520 |
AA_permease_2 |
34 → 449 |
Amino acid permease |
Family |
PF13906 |
AA_permease_C |
556 → 606 |
C-terminus of AA_permease |
Domain |
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Sequence |
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Sequence length |
658 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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