GediPNet logo

SLC6A6 (solute carrier family 6 member 6)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6533
Gene nameGene Name - the full gene name approved by the HGNC.
Solute carrier family 6 member 6
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SLC6A6
SynonymsGene synonyms aliases
HTRDC, TAUT
ChromosomeChromosome number
3
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p25.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative spli
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019132 hsa-miR-335-5p Microarray 18185580
MIRT020030 hsa-miR-375 Microarray 20215506
MIRT050435 hsa-miR-23a-3p CLASH 23622248
MIRT045237 hsa-miR-186-5p CLASH 23622248
MIRT038054 hsa-miR-423-5p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
TP53 Repression 16734743
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005368 Function Taurine transmembrane transporter activity IDA 19074966, 31903486
GO:0005368 Function Taurine transmembrane transporter activity IMP 23519128
GO:0005368 Function Taurine transmembrane transporter activity ISS
GO:0005369 Function Taurine:sodium symporter activity IBA 21873635
GO:0005369 Function Taurine:sodium symporter activity IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P31641
Protein name Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)
Protein function Mediates sodium- and chloride-dependent transport of taurine (PubMed:31345061, PubMed:31903486, PubMed:8010975, PubMed:8382624, PubMed:8654117). Mediates transport of beta-alanine (PubMed:8010975). Can also mediate transport of hypotaurine and g
PDB 9K7B , 9K7N
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00209 SNF
41 568
Sodium:neurotransmitter symporter family
Family
Sequence
Sequence length 620
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Amino acid transport across the plasma membrane
Na+/Cl- dependent neurotransmitter transporters
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Myocardial ischemia Myocardial Ischemia 16214533

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412