SLC6A4 (solute carrier family 6 member 4)

Gene

• Entrez ID: 6532
• Gene name: Solute carrier family 6 member 4
• Gene symbol: SLC6A4
• Synonyms: 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
• Chromosome: 17
• Chromosome location: 17q11.2
• Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs28914832	T>C,G	Risk-factor	Missense variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018862	hsa-miR-335-5p	Microarray	18185580
MIRT053620	hsa-miR-16-5p	qRT-PCR, Western blot	22940131
MIRT438132	hsa-miR-135a-5p	Luciferase reporter assay	24952960
MIRT438132	hsa-miR-135a-5p	Luciferase reporter assay	24952960
MIRT699293	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT699292	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT699291	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT699290	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT699289	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT699288	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT699287	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT699286	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT699285	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT699284	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT699283	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT699282	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT699281	hsa-miR-302e	HITS-CLIP	23313552
MIRT699280	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT699279	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT699278	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT699277	hsa-miR-520b	HITS-CLIP	23313552
MIRT699276	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT699275	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT699274	hsa-miR-520e	HITS-CLIP	23313552
MIRT699273	hsa-miR-552-3p	HITS-CLIP	23313552
MIRT699272	hsa-miR-4418	HITS-CLIP	23313552
MIRT699271	hsa-miR-509-3-5p	HITS-CLIP	23313552
MIRT699270	hsa-miR-509-5p	HITS-CLIP	23313552
MIRT699269	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT699268	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT699267	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT699266	hsa-miR-520h	HITS-CLIP	23313552
MIRT699265	hsa-miR-6890-3p	HITS-CLIP	23313552
MIRT699264	hsa-miR-3934-5p	HITS-CLIP	23313552
MIRT699263	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT699262	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT699261	hsa-miR-3130-3p	HITS-CLIP	23313552
MIRT639481	hsa-miR-1184	HITS-CLIP	23313552
MIRT699260	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT699259	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT699258	hsa-miR-5702	HITS-CLIP	23313552
MIRT699257	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT699256	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT699255	hsa-miR-5095	HITS-CLIP	23313552
MIRT699254	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT699253	hsa-miR-937-5p	HITS-CLIP	23313552
MIRT699252	hsa-miR-7156-3p	HITS-CLIP	23313552
MIRT699251	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT639490	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT639489	hsa-miR-1264	HITS-CLIP	23824327
MIRT639488	hsa-miR-142-5p	HITS-CLIP	23824327
MIRT639487	hsa-miR-5590-3p	HITS-CLIP	23824327
MIRT639486	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT639484	hsa-miR-4287	HITS-CLIP	23824327
MIRT639483	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT639482	hsa-miR-3158-5p	HITS-CLIP	23824327
MIRT639481	hsa-miR-1184	HITS-CLIP	23824327
MIRT639480	hsa-miR-1205	HITS-CLIP	23824327
MIRT639479	hsa-miR-17-3p	HITS-CLIP	23824327
MIRT639478	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT639477	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639476	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639475	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639474	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT639473	hsa-miR-544a	HITS-CLIP	23824327
MIRT639490	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT639489	hsa-miR-1264	HITS-CLIP	23824327
MIRT639488	hsa-miR-142-5p	HITS-CLIP	23824327
MIRT639487	hsa-miR-5590-3p	HITS-CLIP	23824327
MIRT639486	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT639485	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT639484	hsa-miR-4287	HITS-CLIP	23824327
MIRT639483	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT639482	hsa-miR-3158-5p	HITS-CLIP	23824327
MIRT639481	hsa-miR-1184	HITS-CLIP	23824327
MIRT639480	hsa-miR-1205	HITS-CLIP	23824327
MIRT639479	hsa-miR-17-3p	HITS-CLIP	23824327
MIRT639478	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT639477	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639476	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639475	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639474	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT639473	hsa-miR-544a	HITS-CLIP	23824327
MIRT699293	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT699292	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT699291	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT699290	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT699289	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT699288	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT699287	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT699286	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT699285	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT699284	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT699283	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT699282	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT699281	hsa-miR-302e	HITS-CLIP	23313552
MIRT699280	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT699279	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT699278	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT699277	hsa-miR-520b	HITS-CLIP	23313552
MIRT699276	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT699275	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT699274	hsa-miR-520e	HITS-CLIP	23313552
MIRT699273	hsa-miR-552-3p	HITS-CLIP	23313552
MIRT699272	hsa-miR-4418	HITS-CLIP	23313552
MIRT699271	hsa-miR-509-3-5p	HITS-CLIP	23313552
MIRT699270	hsa-miR-509-5p	HITS-CLIP	23313552
MIRT699269	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT699268	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT699267	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT699266	hsa-miR-520h	HITS-CLIP	23313552
MIRT699265	hsa-miR-6890-3p	HITS-CLIP	23313552
MIRT699264	hsa-miR-3934-5p	HITS-CLIP	23313552
MIRT699263	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT699262	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT699261	hsa-miR-3130-3p	HITS-CLIP	23313552
MIRT639481	hsa-miR-1184	HITS-CLIP	23313552
MIRT699260	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT699259	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT699258	hsa-miR-5702	HITS-CLIP	23313552
MIRT699257	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT699256	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT699255	hsa-miR-5095	HITS-CLIP	23313552
MIRT699254	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT699253	hsa-miR-937-5p	HITS-CLIP	23313552
MIRT699252	hsa-miR-7156-3p	HITS-CLIP	23313552
MIRT699251	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT639490	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT639489	hsa-miR-1264	HITS-CLIP	23824327
MIRT639488	hsa-miR-142-5p	HITS-CLIP	23824327
MIRT639487	hsa-miR-5590-3p	HITS-CLIP	23824327
MIRT639486	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT639484	hsa-miR-4287	HITS-CLIP	23824327
MIRT639483	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT639482	hsa-miR-3158-5p	HITS-CLIP	23824327
MIRT639481	hsa-miR-1184	HITS-CLIP	23824327
MIRT639480	hsa-miR-1205	HITS-CLIP	23824327
MIRT639479	hsa-miR-17-3p	HITS-CLIP	23824327
MIRT639478	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT639477	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639476	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639475	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639474	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT639473	hsa-miR-544a	HITS-CLIP	23824327
MIRT639490	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT639489	hsa-miR-1264	HITS-CLIP	23824327
MIRT639488	hsa-miR-142-5p	HITS-CLIP	23824327
MIRT639487	hsa-miR-5590-3p	HITS-CLIP	23824327
MIRT639486	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT639485	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT639484	hsa-miR-4287	HITS-CLIP	23824327
MIRT639483	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT639482	hsa-miR-3158-5p	HITS-CLIP	23824327
MIRT639481	hsa-miR-1184	HITS-CLIP	23824327
MIRT639480	hsa-miR-1205	HITS-CLIP	23824327
MIRT639479	hsa-miR-17-3p	HITS-CLIP	23824327
MIRT639478	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT639477	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639476	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639475	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639474	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT639473	hsa-miR-544a	HITS-CLIP	23824327
MIRT1366351	hsa-miR-141	CLIP-seq
MIRT1366352	hsa-miR-146a	CLIP-seq
MIRT1366353	hsa-miR-146b-5p	CLIP-seq
MIRT1366354	hsa-miR-200a	CLIP-seq
MIRT1366355	hsa-miR-27a	CLIP-seq
MIRT1366356	hsa-miR-27b	CLIP-seq
MIRT1366357	hsa-miR-3140-5p	CLIP-seq
MIRT1366358	hsa-miR-3190	CLIP-seq
MIRT1366359	hsa-miR-3616-5p	CLIP-seq
MIRT1366360	hsa-miR-3647-5p	CLIP-seq
MIRT1366361	hsa-miR-371b-5p	CLIP-seq
MIRT1366362	hsa-miR-3919	CLIP-seq
MIRT1366363	hsa-miR-3925-5p	CLIP-seq
MIRT1366364	hsa-miR-3938	CLIP-seq
MIRT1366365	hsa-miR-4698	CLIP-seq
MIRT1366366	hsa-miR-4729	CLIP-seq
MIRT1366367	hsa-miR-4762-3p	CLIP-seq
MIRT1366368	hsa-miR-4789-5p	CLIP-seq
MIRT1366369	hsa-miR-4795-5p	CLIP-seq
MIRT1366370	hsa-miR-4797-5p	CLIP-seq
MIRT1366371	hsa-miR-4799-5p	CLIP-seq
MIRT1366372	hsa-miR-499a-5p	CLIP-seq
MIRT1366373	hsa-miR-513a-3p	CLIP-seq
MIRT1366374	hsa-miR-513a-5p	CLIP-seq
MIRT1366375	hsa-miR-573	CLIP-seq
MIRT1366376	hsa-miR-579	CLIP-seq
MIRT2108742	hsa-miR-2110	CLIP-seq
MIRT2108743	hsa-miR-3153	CLIP-seq
MIRT2108744	hsa-miR-3173-3p	CLIP-seq
MIRT2108745	hsa-miR-4271	CLIP-seq
MIRT2108746	hsa-miR-4667-5p	CLIP-seq
MIRT2108747	hsa-miR-4695-5p	CLIP-seq
MIRT2108748	hsa-miR-4700-5p	CLIP-seq
MIRT2108749	hsa-miR-4725-3p	CLIP-seq
MIRT2332378	hsa-miR-4282	CLIP-seq
MIRT1366372	hsa-miR-499a-5p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
CTCF	Unknown	15229244;17360901;21309950;23765727
YBX1	Unknown	15229244;17360901;23765727

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001666	Process	Response to hypoxia	IEA
GO:0005326	Function	Neurotransmitter transmembrane transporter activity	ISS
GO:0005335	Function	Serotonin:sodium symporter activity	IBA	21873635
GO:0005335	Function	Serotonin:sodium symporter activity	IDA	8987735
GO:0005335	Function	Serotonin:sodium symporter activity	TAS
GO:0005515	Function	Protein binding	IPI	11343649, 12177201, 16870614, 16882008
GO:0005886	Component	Plasma membrane	IDA	16870614, 17506858
GO:0005886	Component	Plasma membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0005925	Component	Focal adhesion	ISS
GO:0006836	Process	Neurotransmitter transport	ISS
GO:0007584	Process	Response to nutrient	IEA
GO:0007613	Process	Memory	IEA
GO:0007623	Process	Circadian rhythm	IEA
GO:0008504	Function	Monoamine transmembrane transporter activity	IDA	16024787
GO:0008504	Function	Monoamine transmembrane transporter activity	ISS
GO:0009636	Process	Response to toxic substance	IDA	17575980
GO:0010008	Component	Endosome membrane	IEA
GO:0010628	Process	Positive regulation of gene expression	IEA
GO:0012505	Component	Endomembrane system	IDA	17506858
GO:0014064	Process	Positive regulation of serotonin secretion	IEA
GO:0015844	Process	Monoamine transport	IDA	16024787
GO:0017075	Function	Syntaxin-1 binding	IEA
GO:0019811	Function	Cocaine binding	IEA
GO:0021941	Process	Negative regulation of cerebellar granule cell precursor proliferation	IEA
GO:0032227	Process	Negative regulation of synaptic transmission, dopaminergic	IEA
GO:0032355	Process	Response to estradiol	IEA
GO:0035176	Process	Social behavior	ISS
GO:0035725	Process	Sodium ion transmembrane transport	IBA	21873635
GO:0042136	Process	Neurotransmitter biosynthetic process	TAS
GO:0042310	Process	Vasoconstriction	IEA
GO:0042493	Process	Response to drug	IEA
GO:0042713	Process	Sperm ejaculation	IEA
GO:0042802	Function	Identical protein binding	ISS
GO:0043005	Component	Neuron projection	IBA	21873635
GO:0045121	Component	Membrane raft	IDA	16870614
GO:0045202	Component	Synapse	ISS
GO:0045665	Process	Negative regulation of neuron differentiation	IEA
GO:0045787	Process	Positive regulation of cell cycle	IEA
GO:0046621	Process	Negative regulation of organ growth	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0048854	Process	Brain morphogenesis	ISS
GO:0050998	Function	Nitric-oxide synthase binding	IEA
GO:0051015	Function	Actin filament binding	ISS
GO:0051378	Function	Serotonin binding	IBA	21873635
GO:0051610	Process	Serotonin uptake	IBA	21873635
GO:0051610	Process	Serotonin uptake	IDA	8987735, 16870614, 17506858
GO:0051610	Process	Serotonin uptake	IMP	7681602
GO:0051610	Process	Serotonin uptake	ISS
GO:0071300	Process	Cellular response to retinoic acid	IEA
GO:0071321	Process	Cellular response to cGMP	IEA
GO:0090067	Process	Regulation of thalamus size	IMP	18378990
GO:0099055	Component	Integral component of postsynaptic membrane	IEA
GO:0099056	Component	Integral component of presynaptic membrane	IEA
GO:0099154	Component	Serotonergic synapse	IEA

Other IDs

• MIM: 182138
• HGNC: 11050
• e!Ensembl: ENSG00000108576

Protein

• UniProt ID: P31645
• Protein name: Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)
• Protein function: Serotonin transporter that cotransports serotonin with one Na(+) ion in exchange for one K(+) ion and possibly one proton in an overall electroneutral transport cycle. Transports serotonin across the plasma membrane from the extracellular compar
• PDB: 5I6X, 5I6Z, 5I71, 5I73, 5I74, 5I75, 6AWN, 6AWO, 6AWP, 6AWQ, 6DZV, 6DZW, 6DZY, 6DZZ, 6VRH, 6VRK, 6VRL, 6W2B, 6W2C, 7LI6, 7LI7, 7LI8, 7LI9, 7LIA, 7LWD, 7MGW, 7TXT
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03491	5HT_transport_N	24 → 64	Serotonin (5-HT) neurotransmitter transporter, N-terminus	Family
  PF00209	SNF	79 → 600	Sodium:neurotransmitter symporter family	Family

• Sequence:

  METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTR
  HSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLP
  YTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIM
  AWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIH
  RSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGA
  TLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQD
  ALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPAS
  TFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVT
  LTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRIC
  WVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIIT
  PGTFKERIIKSITPETPTEIPCGDIRLNAV

• Sequence length: 630

Pathways

KEGG:

Synaptic vesicle cycle
Serotonergic synapse

Reactome:

Serotonin clearance from the synaptic cleft

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Autism	Autistic Disorder	rs121964908, rs121912597, rs2710102, rs7794745, rs142990298, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699, rs1553510219, rs1684182454, rs1559060428, rs1553510677, rs1576352885, rs1574152522, rs1574152672, rs1696658542, rs1751123722, rs1750373491, rs1751075634	16721604, 17203304, 20649385, 17280648, 9152989
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	18583979

Unknown
Disease name	Disease term	dbSNP ID	References
Affective psychosis	Affective Disorders, Psychotic		18264772, 20031235
Anhedonia	Anhedonia		22094432, 18690111
Anxiety disorder	Anxiety, Anxiety Disorders, Anxiety States, Neurotic		17101915, 15642926, 18686203
As if personality	As If Personality		17000009
Asperger syndrome	Asperger Syndrome		18197083
Bipolar disorder	Bipolar Disorder, Depression, Bipolar		16395126, 23931339, 25019689, 25194461, 11772685, 24229495, 25219494, 11386982, 10898918, 16395126, 11772685
Cognitive disorder	Cognition Disorders		23209555
Compulsive hoarding	Compulsive hoarding
Dysthymic disorder	Dysthymic Disorder		15312818
Impulse-ridden personality	Impulse-Ridden Personality		17000009
Inadequate personality	Inadequate Personality		17000009
Involutional depression	Involutional Depression		16055263
Involutional paraphrenia	Involutional paraphrenia		16055263
Manic disorder	Manic, Manic Disorder		16395126, 11772685
Melancholia	Melancholia		14593433, 18050262, 21843009, 18686203, 12898347, 18458677, 22247094, 20588071, 9799087
Memory disorders	Memory Disorders		18686203, 18661256
Age-related memory disorders	Age-Related Memory Disorders		18661256, 18686203
Mental depression	Mental Depression, Endogenous depression, Depressive disorder, Unipolar Depression, Depressive Syndrome, Depression, Postpartum, Recurrent depression, Depression, Neurotic, Chronic depression, Severe depression, Major Depressive Disorder	rs587778876, rs587778877	25583186, 23588187, 25422957, 25510949, 24972302, 21843009, 18686203, 12898347, 18458677, 12898347, 25422957, 18686203, 21843009, 25583186, 25510949, 24972302, 18458677, 23588187, 18686203, 25650523, 25510949, 24679990, 24972302, 18458677, 12898347, 21843009, 25226554, 18458677, 12898347, 21843009, 18686203, 23394411, 21997575, 22209125, 24882202, 23149286, 22100130, 22840631, 19541292, 21843009, 12898347, 18458677, 18686203, 24338983, 24323294, 21165304, 22847957, 19567893, 25226554, 25510949, 24972302, 24679990, 16055263, 25650523
Mood disorder	Dysphoric mood, Mood Disorders		17079080, 20462563, 22309725, 19878141, 25547397, 24862560, 25596490, 24972302, 24438559
Obsessive-compulsive disorder	Obsessive-Compulsive Disorder		17101915, 18197083
Personality disorders	Personality Disorders		17000009
Psychosis	Psychosis, Involutional		16055263
Seasonal affective disorder	Seasonal Affective Disorder		23475832, 24260145, 18663369, 24407753, 17882235
Skin-picking	Skin-picking