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NDRG4 (NDRG family member 4)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
65009
Gene nameGene Name - the full gene name approved by the HGNC.
NDRG family member 4
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
NDRG4
SynonymsGene synonyms aliases
BDM1, SMAP-8, SMAP8
ChromosomeChromosome number
16
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q21
SummarySummary of gene provided in NCBI Entrez Gene.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes an
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT612052 hsa-miR-8485 HITS-CLIP 23313552
MIRT519153 hsa-miR-4789-3p HITS-CLIP 23313552
MIRT612052 hsa-miR-8485 HITS-CLIP 23824327
MIRT612051 hsa-miR-329-3p HITS-CLIP 23824327
MIRT612050 hsa-miR-362-3p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001947 Process Heart looping ISS
GO:0003674 Function Molecular_function ND
GO:0005515 Function Protein binding IPI 25416956
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005737 Component Cytoplasm IDA 12755708
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9ULP0
Protein name Protein NDRG4 (Brain development-related molecule 1) (N-myc downstream-regulated gene 4 protein) (Vascular smooth muscle cell-associated protein 8) (SMAP-8)
Protein function Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance gro
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03096 Ndr
8 290
Ndr family
Domain
Sequence
Sequence length 352
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 29483656

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