IKZF4 (IKAROS family zinc finger 4)

Gene

• Entrez ID: 64375
• Gene name: IKAROS family zinc finger 4
• Gene symbol: IKZF4
• Synonyms: EOS, ZNFN1A4
• Chromosome: 12
• Chromosome location: 12q13.2
• Summary: Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020311	hsa-miR-130b-3p	Sequencing	20371350
MIRT028174	hsa-miR-93-5p	Sequencing	20371350
MIRT051190	hsa-miR-16-5p	CLASH	23622248
MIRT049855	hsa-miR-32-5p	CLASH	23622248
MIRT047855	hsa-miR-30c-5p	CLASH	23622248
MIRT046120	hsa-miR-30b-5p	CLASH	23622248
MIRT054202	hsa-miR-125b-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	22723551
MIRT511370	hsa-miR-548c-3p	HITS-CLIP	21572407
MIRT511369	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT338335	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT338333	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT338331	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT338334	hsa-miR-3924	HITS-CLIP	21572407
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT338333	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT523021	hsa-miR-3920	PAR-CLIP	20371350
MIRT567156	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT338334	hsa-miR-3924	PAR-CLIP	20371350
MIRT567155	hsa-miR-3192-3p	PAR-CLIP	20371350
MIRT567154	hsa-miR-4762-3p	PAR-CLIP	20371350
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT338333	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT338334	hsa-miR-3924	PAR-CLIP	21572407
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT338333	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT338334	hsa-miR-3924	PAR-CLIP	21572407
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT523023	hsa-miR-4731-3p	PAR-CLIP	23446348
MIRT523022	hsa-miR-4801	PAR-CLIP	23446348
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT338333	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT523021	hsa-miR-3920	PAR-CLIP	23446348
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT338334	hsa-miR-3924	PAR-CLIP	23446348
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT338333	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT338334	hsa-miR-3924	PAR-CLIP	23446348
MIRT511370	hsa-miR-548c-3p	HITS-CLIP	21572407
MIRT511369	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT338335	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT338333	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT338331	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT338334	hsa-miR-3924	HITS-CLIP	21572407
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT338333	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT523021	hsa-miR-3920	PAR-CLIP	20371350
MIRT567156	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT338334	hsa-miR-3924	PAR-CLIP	20371350
MIRT567155	hsa-miR-3192-3p	PAR-CLIP	20371350
MIRT567154	hsa-miR-4762-3p	PAR-CLIP	20371350
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT338333	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT338334	hsa-miR-3924	PAR-CLIP	21572407
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT338333	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT338334	hsa-miR-3924	PAR-CLIP	21572407
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT523023	hsa-miR-4731-3p	PAR-CLIP	23446348
MIRT523022	hsa-miR-4801	PAR-CLIP	23446348
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT338333	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT523021	hsa-miR-3920	PAR-CLIP	23446348
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT338334	hsa-miR-3924	PAR-CLIP	23446348
MIRT511370	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT511369	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT338335	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT338333	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT338331	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT338334	hsa-miR-3924	PAR-CLIP	23446348
MIRT1063341	hsa-miR-101	CLIP-seq
MIRT1063342	hsa-miR-1252	CLIP-seq
MIRT1063343	hsa-miR-1253	CLIP-seq
MIRT1063344	hsa-miR-125a-3p	CLIP-seq
MIRT1063345	hsa-miR-1294	CLIP-seq
MIRT1063346	hsa-miR-1298	CLIP-seq
MIRT1063347	hsa-miR-130a	CLIP-seq
MIRT1063348	hsa-miR-130b	CLIP-seq
MIRT1063349	hsa-miR-1323	CLIP-seq
MIRT1063350	hsa-miR-144	CLIP-seq
MIRT1063351	hsa-miR-185	CLIP-seq
MIRT1063352	hsa-miR-199a-3p	CLIP-seq
MIRT1063353	hsa-miR-199b-3p	CLIP-seq
MIRT1063354	hsa-miR-205	CLIP-seq
MIRT1063355	hsa-miR-22	CLIP-seq
MIRT1063356	hsa-miR-221	CLIP-seq
MIRT1063357	hsa-miR-222	CLIP-seq
MIRT1063358	hsa-miR-300	CLIP-seq
MIRT1063359	hsa-miR-301a	CLIP-seq
MIRT1063360	hsa-miR-301b	CLIP-seq
MIRT1063361	hsa-miR-3126-5p	CLIP-seq
MIRT1063362	hsa-miR-3129-5p	CLIP-seq
MIRT1063363	hsa-miR-3140-5p	CLIP-seq
MIRT1063364	hsa-miR-3157-5p	CLIP-seq
MIRT1063365	hsa-miR-3173-3p	CLIP-seq
MIRT1063366	hsa-miR-3174	CLIP-seq
MIRT1063367	hsa-miR-3179	CLIP-seq
MIRT1063368	hsa-miR-3202	CLIP-seq
MIRT1063369	hsa-miR-338-5p	CLIP-seq
MIRT1063370	hsa-miR-3666	CLIP-seq
MIRT1063371	hsa-miR-381	CLIP-seq
MIRT1063372	hsa-miR-3915	CLIP-seq
MIRT1063373	hsa-miR-3928	CLIP-seq
MIRT1063374	hsa-miR-3934	CLIP-seq
MIRT1063375	hsa-miR-4271	CLIP-seq
MIRT1063376	hsa-miR-4295	CLIP-seq
MIRT1063377	hsa-miR-4306	CLIP-seq
MIRT1063378	hsa-miR-4316	CLIP-seq
MIRT1063379	hsa-miR-4419a	CLIP-seq
MIRT1063380	hsa-miR-4426	CLIP-seq
MIRT1063381	hsa-miR-4428	CLIP-seq
MIRT1063382	hsa-miR-4434	CLIP-seq
MIRT1063383	hsa-miR-4435	CLIP-seq
MIRT1063384	hsa-miR-4437	CLIP-seq
MIRT1063385	hsa-miR-4476	CLIP-seq
MIRT1063386	hsa-miR-4481	CLIP-seq
MIRT1063387	hsa-miR-4510	CLIP-seq
MIRT1063388	hsa-miR-4516	CLIP-seq
MIRT1063389	hsa-miR-4533	CLIP-seq
MIRT1063390	hsa-miR-454	CLIP-seq
MIRT1063391	hsa-miR-4540	CLIP-seq
MIRT1063392	hsa-miR-4644	CLIP-seq
MIRT1063393	hsa-miR-4647	CLIP-seq
MIRT1063394	hsa-miR-4654	CLIP-seq
MIRT1063395	hsa-miR-4662b	CLIP-seq
MIRT1063396	hsa-miR-4666-3p	CLIP-seq
MIRT1063397	hsa-miR-4671-3p	CLIP-seq
MIRT1063398	hsa-miR-4676-5p	CLIP-seq
MIRT1063399	hsa-miR-4683	CLIP-seq
MIRT1063400	hsa-miR-4691-3p	CLIP-seq
MIRT1063401	hsa-miR-4693-3p	CLIP-seq
MIRT1063402	hsa-miR-4699-3p	CLIP-seq
MIRT1063403	hsa-miR-4712-5p	CLIP-seq
MIRT1063404	hsa-miR-4725-3p	CLIP-seq
MIRT1063405	hsa-miR-4745-5p	CLIP-seq
MIRT1063406	hsa-miR-4747-5p	CLIP-seq
MIRT1063407	hsa-miR-4769-5p	CLIP-seq
MIRT1063408	hsa-miR-499a-5p	CLIP-seq
MIRT1063409	hsa-miR-513c	CLIP-seq
MIRT1063410	hsa-miR-514b-5p	CLIP-seq
MIRT1063411	hsa-miR-548o	CLIP-seq
MIRT1063412	hsa-miR-548v	CLIP-seq
MIRT1063413	hsa-miR-575	CLIP-seq
MIRT1063414	hsa-miR-582-5p	CLIP-seq
MIRT1063415	hsa-miR-600	CLIP-seq
MIRT1063416	hsa-miR-656	CLIP-seq
MIRT1063417	hsa-miR-664	CLIP-seq
MIRT1063418	hsa-miR-764	CLIP-seq
MIRT1063419	hsa-miR-770-5p	CLIP-seq
MIRT1063420	hsa-miR-921	CLIP-seq
MIRT1063341	hsa-miR-101	CLIP-seq
MIRT2014956	hsa-miR-10a	CLIP-seq
MIRT2014957	hsa-miR-10b	CLIP-seq
MIRT2014958	hsa-miR-1231	CLIP-seq
MIRT1063344	hsa-miR-125a-3p	CLIP-seq
MIRT1063345	hsa-miR-1294	CLIP-seq
MIRT1063350	hsa-miR-144	CLIP-seq
MIRT1063351	hsa-miR-185	CLIP-seq
MIRT1063352	hsa-miR-199a-3p	CLIP-seq
MIRT1063353	hsa-miR-199b-3p	CLIP-seq
MIRT1063361	hsa-miR-3126-5p	CLIP-seq
MIRT1063362	hsa-miR-3129-5p	CLIP-seq
MIRT1063363	hsa-miR-3140-5p	CLIP-seq
MIRT2014959	hsa-miR-3150b-3p	CLIP-seq
MIRT1063364	hsa-miR-3157-5p	CLIP-seq
MIRT2014960	hsa-miR-3160-3p	CLIP-seq
MIRT2014961	hsa-miR-3166	CLIP-seq
MIRT1063365	hsa-miR-3173-3p	CLIP-seq
MIRT1063366	hsa-miR-3174	CLIP-seq
MIRT2014962	hsa-miR-3185	CLIP-seq
MIRT2014963	hsa-miR-3192	CLIP-seq
MIRT1063368	hsa-miR-3202	CLIP-seq
MIRT2014964	hsa-miR-3616-3p	CLIP-seq
MIRT2014965	hsa-miR-3659	CLIP-seq
MIRT1063373	hsa-miR-3928	CLIP-seq
MIRT1063374	hsa-miR-3934	CLIP-seq
MIRT2014966	hsa-miR-4276	CLIP-seq
MIRT2014967	hsa-miR-4280	CLIP-seq
MIRT2014968	hsa-miR-4300	CLIP-seq
MIRT2014969	hsa-miR-4302	CLIP-seq
MIRT1063377	hsa-miR-4306	CLIP-seq
MIRT2014970	hsa-miR-4314	CLIP-seq
MIRT1063379	hsa-miR-4419a	CLIP-seq
MIRT1063383	hsa-miR-4435	CLIP-seq
MIRT1063384	hsa-miR-4437	CLIP-seq
MIRT1063385	hsa-miR-4476	CLIP-seq
MIRT1063387	hsa-miR-4510	CLIP-seq
MIRT1063392	hsa-miR-4644	CLIP-seq
MIRT2014971	hsa-miR-4646-5p	CLIP-seq
MIRT2014972	hsa-miR-4658	CLIP-seq
MIRT2014973	hsa-miR-4672	CLIP-seq
MIRT1063398	hsa-miR-4676-5p	CLIP-seq
MIRT1063399	hsa-miR-4683	CLIP-seq
MIRT2014974	hsa-miR-4689	CLIP-seq
MIRT1063400	hsa-miR-4691-3p	CLIP-seq
MIRT2014975	hsa-miR-4710	CLIP-seq
MIRT2014976	hsa-miR-4711-3p	CLIP-seq
MIRT1063403	hsa-miR-4712-5p	CLIP-seq
MIRT2014977	hsa-miR-4721	CLIP-seq
MIRT2014978	hsa-miR-4784	CLIP-seq
MIRT1063408	hsa-miR-499a-5p	CLIP-seq
MIRT2014979	hsa-miR-574-5p	CLIP-seq
MIRT1063413	hsa-miR-575	CLIP-seq
MIRT1063418	hsa-miR-764	CLIP-seq
MIRT1063419	hsa-miR-770-5p	CLIP-seq
MIRT2014980	hsa-miR-920	CLIP-seq
MIRT1063420	hsa-miR-921	CLIP-seq
MIRT2014981	hsa-miR-922	CLIP-seq
MIRT2247315	hsa-miR-106a	CLIP-seq
MIRT2247316	hsa-miR-106b	CLIP-seq
MIRT1063344	hsa-miR-125a-3p	CLIP-seq
MIRT2247317	hsa-miR-1283	CLIP-seq
MIRT2247318	hsa-miR-146b-3p	CLIP-seq
MIRT2247319	hsa-miR-17	CLIP-seq
MIRT1063351	hsa-miR-185	CLIP-seq
MIRT1063352	hsa-miR-199a-3p	CLIP-seq
MIRT1063353	hsa-miR-199b-3p	CLIP-seq
MIRT2247320	hsa-miR-20a	CLIP-seq
MIRT2247321	hsa-miR-20b	CLIP-seq
MIRT2247322	hsa-miR-28-5p	CLIP-seq
MIRT1063362	hsa-miR-3129-5p	CLIP-seq
MIRT2247323	hsa-miR-3139	CLIP-seq
MIRT2014961	hsa-miR-3166	CLIP-seq
MIRT2247324	hsa-miR-3173-5p	CLIP-seq
MIRT1063366	hsa-miR-3174	CLIP-seq
MIRT2014963	hsa-miR-3192	CLIP-seq
MIRT2014964	hsa-miR-3616-3p	CLIP-seq
MIRT1063374	hsa-miR-3934	CLIP-seq
MIRT1063377	hsa-miR-4306	CLIP-seq
MIRT1063379	hsa-miR-4419a	CLIP-seq
MIRT1063383	hsa-miR-4435	CLIP-seq
MIRT2247325	hsa-miR-4436b-5p	CLIP-seq
MIRT2247326	hsa-miR-4496	CLIP-seq
MIRT1063387	hsa-miR-4510	CLIP-seq
MIRT1063391	hsa-miR-4540	CLIP-seq
MIRT1063392	hsa-miR-4644	CLIP-seq
MIRT2014973	hsa-miR-4672	CLIP-seq
MIRT1063398	hsa-miR-4676-5p	CLIP-seq
MIRT2247327	hsa-miR-4796-3p	CLIP-seq
MIRT2247328	hsa-miR-519d	CLIP-seq
MIRT2247329	hsa-miR-520d-5p	CLIP-seq
MIRT2247330	hsa-miR-524-5p	CLIP-seq
MIRT1063413	hsa-miR-575	CLIP-seq
MIRT2247331	hsa-miR-597	CLIP-seq
MIRT2247332	hsa-miR-610	CLIP-seq
MIRT2247333	hsa-miR-708	CLIP-seq
MIRT1063418	hsa-miR-764	CLIP-seq
MIRT2247334	hsa-miR-874	CLIP-seq
MIRT1063420	hsa-miR-921	CLIP-seq
MIRT2014981	hsa-miR-922	CLIP-seq
MIRT2247335	hsa-miR-93	CLIP-seq
MIRT1063351	hsa-miR-185	CLIP-seq
MIRT2014963	hsa-miR-3192	CLIP-seq
MIRT1063377	hsa-miR-4306	CLIP-seq
MIRT1063392	hsa-miR-4644	CLIP-seq
MIRT2451681	hsa-miR-3189-3p	CLIP-seq
MIRT2451682	hsa-miR-3674	CLIP-seq
MIRT2451683	hsa-miR-3918	CLIP-seq
MIRT2247325	hsa-miR-4436b-5p	CLIP-seq
MIRT1063386	hsa-miR-4481	CLIP-seq
MIRT2451684	hsa-miR-4511	CLIP-seq
MIRT1063394	hsa-miR-4654	CLIP-seq
MIRT2451685	hsa-miR-4687-3p	CLIP-seq
MIRT1063401	hsa-miR-4693-3p	CLIP-seq
MIRT1063405	hsa-miR-4745-5p	CLIP-seq
MIRT1063407	hsa-miR-4769-5p	CLIP-seq
MIRT2451686	hsa-miR-4773	CLIP-seq
MIRT2451687	hsa-miR-548b-3p	CLIP-seq
MIRT2451688	hsa-miR-643	CLIP-seq
MIRT2451689	hsa-miR-663b	CLIP-seq
MIRT2451690	hsa-miR-665	CLIP-seq
MIRT2451682	hsa-miR-3674	CLIP-seq
MIRT2247325	hsa-miR-4436b-5p	CLIP-seq
MIRT2451688	hsa-miR-643	CLIP-seq
MIRT2451682	hsa-miR-3674	CLIP-seq
MIRT2550747	hsa-miR-4269	CLIP-seq
MIRT2550748	hsa-miR-4301	CLIP-seq
MIRT2247325	hsa-miR-4436b-5p	CLIP-seq
MIRT2550749	hsa-miR-4514	CLIP-seq
MIRT2550750	hsa-miR-4692	CLIP-seq
MIRT2550751	hsa-miR-4742-5p	CLIP-seq
MIRT2550752	hsa-miR-494	CLIP-seq
MIRT2451688	hsa-miR-643	CLIP-seq
MIRT2682716	hsa-miR-25	CLIP-seq
MIRT2682717	hsa-miR-32	CLIP-seq
MIRT2682718	hsa-miR-363	CLIP-seq
MIRT2682719	hsa-miR-367	CLIP-seq
MIRT2451682	hsa-miR-3674	CLIP-seq
MIRT2682720	hsa-miR-3977	CLIP-seq
MIRT2682721	hsa-miR-4325	CLIP-seq
MIRT2247325	hsa-miR-4436b-5p	CLIP-seq
MIRT2451688	hsa-miR-643	CLIP-seq
MIRT2682722	hsa-miR-92a	CLIP-seq
MIRT2682723	hsa-miR-92b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0003700	Function	DNA-binding transcription factor activity	IBA	21873635
GO:0003700	Function	DNA-binding transcription factor activity	TAS	10978333
GO:0005515	Function	Protein binding	IPI	15491138, 32296183
GO:0005634	Component	Nucleus	TAS	10978333
GO:0005654	Component	Nucleoplasm	IDA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0008270	Function	Zinc ion binding	IMP	15491138
GO:0016604	Component	Nuclear body	IDA
GO:0019904	Function	Protein domain specific binding	IPI	15491138
GO:0032991	Component	Protein-containing complex	IMP	15491138
GO:0043425	Function	BHLH transcription factor binding	IEA
GO:0045892	Process	Negative regulation of transcription, DNA-templated	TAS	10978333
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0051260	Process	Protein homooligomerization	IMP	15491138

Other IDs

• MIM: 606239
• HGNC: 13179
• e!Ensembl: ENSG00000123411

Protein

• UniProt ID: Q9H2S9
• Protein name: Zinc finger protein Eos (Ikaros family zinc finger protein 4)
• Protein function: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be
• PDB: 2MA7
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	187 → 209	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	215 → 237	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	248 → 271	Zinc finger, C2H2 type	Domain

• Sequence:

  MHTPPALPRRFQGGGRVRTPGSHRQGKDNLERDPSGGCVPDFLPQAQDSNHFIMESLFCE
  SSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLL
  EKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRS
  HTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVS
  SPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQPGDEIRDLEMVPD
  SMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELV
  AHHSLEPGFGSSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSRE
  AGEGPEDLADGGPLLYRPRGPLTDPGASPSNGCQDSTDTESNHEDRVAGVVSLPQGPPPQ
  PPPTIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFL
  DHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG

• Sequence length: 585

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Asthma	Asthma	rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283	21804548
Diabetes mellitus	Diabetes Mellitus, Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs4402960, rs1362648752, rs3745368, rs3792267, rs3842570, rs5030952, rs2975760, rs119489103, rs7903146, rs12255372, rs11196205, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs137852740, rs137852786, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs80356663, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356666, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs387906779, rs141804752, rs182349376, rs184917682, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs61736969, rs587783673, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs797045623, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs1553638903, rs1553638909, rs948820149, rs371977235, rs1553784995, rs76474829, rs200998587, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs776793516, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	18198356, 21829393

Unknown
Disease name	Disease term	dbSNP ID	References
Alopecia areata	Alopecia Areata		20596022
Vitiligo	Vitiligo		22561518, 27723757