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ELSPBP1 (epididymal sperm binding protein 1)
Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
64100
Gene nameGene Name - the full gene name approved by the HGNC.
Epididymal sperm binding protein 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ELSPBP1
SynonymsGene synonyms aliases
E12, EDDM12, EL149, HE12
ChromosomeChromosome number
19
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19q13.33
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the sperm-coating protein family of epididymal origin. This protein and its canine homolog are the first known examples of proteins with four tandemly arranged fibronectin type 2 (Fn2) domains in the Fn2-module
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT1984937 hsa-miR-3145-3p CLIP-seq
MIRT1984938 hsa-miR-4699-5p CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005576 Component Extracellular region IEA
GO:0007338 Process Single fertilization IEA
GO:0008201 Function Heparin binding IBA 21873635
GO:0009986 Component Cell surface IBA 21873635
GO:0048240 Process Sperm capacitation IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q96BH3
Protein name Epididymal sperm-binding protein 1 (Epididymal secretory protein 12) (hE12)
Protein function Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00040 fn2
29 → 66
Fibronectin type II domain
 Domain
PF00040 fn2
74 → 115
Fibronectin type II domain
 Domain
PF00040 fn2
129 → 168
Fibronectin type II domain
 Domain
PF00040 fn2
182 → 223
Fibronectin type II domain
 Domain
Sequence
Sequence length 223
Interactions View interactions
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Causal
Disease name Disease term dbSNP ID References
Asthma Childhood asthma rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 29551627

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