Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6367 |
Gene nameGene Name - the full gene name approved by the HGNC.
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C-C motif chemokine ligand 22 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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CCL22 |
SynonymsGene synonyms aliases
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A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1 |
ChromosomeChromosome number
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16 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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16q21 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized |
miRNAmiRNA information provided by mirtarbase database.
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Transcription factors
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Transcription factor |
Regulation |
Reference |
NFKB1 |
Activation |
17018379 |
RELA |
Activation |
17018379 |
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
O00626 |
Protein name |
C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)] |
Protein function |
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for pr |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00048 |
IL8 |
34 → 91 |
Small cytokines (intecrine/chemokine), interleukin-8 like |
Domain |
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Sequence |
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Sequence length |
93 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Dermatitis |
Dermatitis, Atopic |
rs61816761, rs150597413, rs138726443, rs201356558, rs149484917, rs372754256, rs747301529, rs567795279, rs745915174 |
22125604, 18249437 |
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