ZDBF2 (zinc finger DBF-type containing 2)

Gene

• Entrez ID: 57683
• Gene name: Zinc finger DBF-type containing 2
• Gene symbol: ZDBF2
• Synonyms: Slx9
• Chromosome: 2
• Chromosome location: 2q33.3
• Summary: This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provi

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT681054	hsa-miR-148a-5p	HITS-CLIP	23706177
MIRT681053	hsa-miR-1247-3p	HITS-CLIP	23706177
MIRT681052	hsa-miR-610	HITS-CLIP	23706177
MIRT681051	hsa-miR-6134	HITS-CLIP	23706177
MIRT681050	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681049	hsa-miR-6086	HITS-CLIP	23706177
MIRT681048	hsa-miR-4746-3p	HITS-CLIP	23706177
MIRT681047	hsa-miR-3689d	HITS-CLIP	23706177
MIRT681046	hsa-miR-6851-5p	HITS-CLIP	23706177
MIRT681045	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT681044	hsa-miR-4792	HITS-CLIP	23706177
MIRT681043	hsa-miR-6880-5p	HITS-CLIP	23706177
MIRT681042	hsa-miR-7847-3p	HITS-CLIP	23706177
MIRT439240	hsa-miR-493-5p	HITS-CLIP	24374217
MIRT439240	hsa-miR-493-5p	HITS-CLIP	24374217
MIRT681054	hsa-miR-148a-5p	HITS-CLIP	23706177
MIRT681053	hsa-miR-1247-3p	HITS-CLIP	23706177
MIRT681052	hsa-miR-610	HITS-CLIP	23706177
MIRT681051	hsa-miR-6134	HITS-CLIP	23706177
MIRT681050	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681049	hsa-miR-6086	HITS-CLIP	23706177
MIRT681048	hsa-miR-4746-3p	HITS-CLIP	23706177
MIRT681047	hsa-miR-3689d	HITS-CLIP	23706177
MIRT681046	hsa-miR-6851-5p	HITS-CLIP	23706177
MIRT681045	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT681044	hsa-miR-4792	HITS-CLIP	23706177
MIRT681043	hsa-miR-6880-5p	HITS-CLIP	23706177
MIRT681042	hsa-miR-7847-3p	HITS-CLIP	23706177
MIRT1507596	hsa-miR-1183	CLIP-seq
MIRT1507597	hsa-miR-1245	CLIP-seq
MIRT1507598	hsa-miR-1252	CLIP-seq
MIRT1507599	hsa-miR-1285	CLIP-seq
MIRT1507600	hsa-miR-129-5p	CLIP-seq
MIRT1507601	hsa-miR-155	CLIP-seq
MIRT1507602	hsa-miR-186	CLIP-seq
MIRT1507603	hsa-miR-203	CLIP-seq
MIRT1507604	hsa-miR-2114	CLIP-seq
MIRT1507605	hsa-miR-2276	CLIP-seq
MIRT1507606	hsa-miR-23a	CLIP-seq
MIRT1507607	hsa-miR-23b	CLIP-seq
MIRT1507608	hsa-miR-23c	CLIP-seq
MIRT1507609	hsa-miR-24	CLIP-seq
MIRT1507610	hsa-miR-2861	CLIP-seq
MIRT1507611	hsa-miR-297	CLIP-seq
MIRT1507612	hsa-miR-3120-5p	CLIP-seq
MIRT1507613	hsa-miR-3129-3p	CLIP-seq
MIRT1507614	hsa-miR-3150b-3p	CLIP-seq
MIRT1507615	hsa-miR-3163	CLIP-seq
MIRT1507616	hsa-miR-3187-5p	CLIP-seq
MIRT1507617	hsa-miR-3188	CLIP-seq
MIRT1507618	hsa-miR-323-3p	CLIP-seq
MIRT1507619	hsa-miR-3612	CLIP-seq
MIRT1507620	hsa-miR-3613-3p	CLIP-seq
MIRT1507621	hsa-miR-3622b-5p	CLIP-seq
MIRT1507622	hsa-miR-3646	CLIP-seq
MIRT1507623	hsa-miR-3647-3p	CLIP-seq
MIRT1507624	hsa-miR-3653	CLIP-seq
MIRT1507625	hsa-miR-3658	CLIP-seq
MIRT1507626	hsa-miR-3664-5p	CLIP-seq
MIRT1507627	hsa-miR-3672	CLIP-seq
MIRT1507628	hsa-miR-3688-3p	CLIP-seq
MIRT1507629	hsa-miR-3692	CLIP-seq
MIRT1507630	hsa-miR-371-5p	CLIP-seq
MIRT1507631	hsa-miR-371b-5p	CLIP-seq
MIRT1507632	hsa-miR-3929	CLIP-seq
MIRT1507633	hsa-miR-3945	CLIP-seq
MIRT1507634	hsa-miR-409-3p	CLIP-seq
MIRT1507635	hsa-miR-410	CLIP-seq
MIRT1507636	hsa-miR-412	CLIP-seq
MIRT1507637	hsa-miR-4253	CLIP-seq
MIRT1507638	hsa-miR-4284	CLIP-seq
MIRT1507639	hsa-miR-4419b	CLIP-seq
MIRT1507640	hsa-miR-4436b-5p	CLIP-seq
MIRT1507641	hsa-miR-4474-5p	CLIP-seq
MIRT1507642	hsa-miR-4477a	CLIP-seq
MIRT1507643	hsa-miR-4478	CLIP-seq
MIRT1507644	hsa-miR-4505	CLIP-seq
MIRT1507645	hsa-miR-4520a-3p	CLIP-seq
MIRT1507646	hsa-miR-4520b-3p	CLIP-seq
MIRT1507647	hsa-miR-4522	CLIP-seq
MIRT1507648	hsa-miR-4635	CLIP-seq
MIRT1507649	hsa-miR-4666-5p	CLIP-seq
MIRT1507650	hsa-miR-4687-3p	CLIP-seq
MIRT1507651	hsa-miR-4689	CLIP-seq
MIRT1507652	hsa-miR-4695-5p	CLIP-seq
MIRT1507653	hsa-miR-4698	CLIP-seq
MIRT1507654	hsa-miR-4762-3p	CLIP-seq
MIRT1507655	hsa-miR-4766-5p	CLIP-seq
MIRT1507656	hsa-miR-4772-3p	CLIP-seq
MIRT1507657	hsa-miR-4775	CLIP-seq
MIRT1507658	hsa-miR-4778-5p	CLIP-seq
MIRT1507659	hsa-miR-4781-3p	CLIP-seq
MIRT1507660	hsa-miR-4784	CLIP-seq
MIRT1507661	hsa-miR-4802-3p	CLIP-seq
MIRT1507662	hsa-miR-518a-5p	CLIP-seq
MIRT1507663	hsa-miR-526b	CLIP-seq
MIRT1507664	hsa-miR-527	CLIP-seq
MIRT1507665	hsa-miR-544	CLIP-seq
MIRT1507666	hsa-miR-548c-3p	CLIP-seq
MIRT1507667	hsa-miR-548u	CLIP-seq
MIRT1507668	hsa-miR-552	CLIP-seq
MIRT1507669	hsa-miR-567	CLIP-seq
MIRT1507670	hsa-miR-568	CLIP-seq
MIRT1507671	hsa-miR-586	CLIP-seq
MIRT1507672	hsa-miR-590-3p	CLIP-seq
MIRT1507673	hsa-miR-599	CLIP-seq
MIRT1507674	hsa-miR-612	CLIP-seq
MIRT1507675	hsa-miR-618	CLIP-seq
MIRT1507676	hsa-miR-650	CLIP-seq
MIRT1507677	hsa-miR-943	CLIP-seq
MIRT1507606	hsa-miR-23a	CLIP-seq
MIRT1507607	hsa-miR-23b	CLIP-seq
MIRT1507608	hsa-miR-23c	CLIP-seq
MIRT1507609	hsa-miR-24	CLIP-seq
MIRT2152885	hsa-miR-2909	CLIP-seq
MIRT2152886	hsa-miR-3606	CLIP-seq
MIRT1507627	hsa-miR-3672	CLIP-seq
MIRT2152887	hsa-miR-3926	CLIP-seq
MIRT2152888	hsa-miR-4278	CLIP-seq
MIRT1507638	hsa-miR-4284	CLIP-seq
MIRT2152889	hsa-miR-4433	CLIP-seq
MIRT2152890	hsa-miR-4459	CLIP-seq
MIRT2152891	hsa-miR-4668-5p	CLIP-seq
MIRT1507653	hsa-miR-4698	CLIP-seq
MIRT2152892	hsa-miR-4768-3p	CLIP-seq
MIRT2152893	hsa-miR-4786-5p	CLIP-seq
MIRT2152894	hsa-miR-548s	CLIP-seq
MIRT2152895	hsa-miR-769-5p	CLIP-seq
MIRT1507677	hsa-miR-943	CLIP-seq
MIRT1507604	hsa-miR-2114	CLIP-seq
MIRT1507606	hsa-miR-23a	CLIP-seq
MIRT1507607	hsa-miR-23b	CLIP-seq
MIRT1507608	hsa-miR-23c	CLIP-seq
MIRT2373223	hsa-miR-2682	CLIP-seq
MIRT2373224	hsa-miR-2964a-3p	CLIP-seq
MIRT2373225	hsa-miR-302f	CLIP-seq
MIRT1507617	hsa-miR-3188	CLIP-seq
MIRT2373226	hsa-miR-3197	CLIP-seq
MIRT2373227	hsa-miR-3656	CLIP-seq
MIRT1507629	hsa-miR-3692	CLIP-seq
MIRT1507632	hsa-miR-3929	CLIP-seq
MIRT1507636	hsa-miR-412	CLIP-seq
MIRT1507639	hsa-miR-4419b	CLIP-seq
MIRT2373228	hsa-miR-4423-3p	CLIP-seq
MIRT1507640	hsa-miR-4436b-5p	CLIP-seq
MIRT1507641	hsa-miR-4474-5p	CLIP-seq
MIRT1507643	hsa-miR-4478	CLIP-seq
MIRT2373229	hsa-miR-449c	CLIP-seq
MIRT2373230	hsa-miR-4649-3p	CLIP-seq
MIRT1507653	hsa-miR-4698	CLIP-seq
MIRT2373231	hsa-miR-4722-5p	CLIP-seq
MIRT2152892	hsa-miR-4768-3p	CLIP-seq
MIRT2373232	hsa-miR-485-5p	CLIP-seq
MIRT1507662	hsa-miR-518a-5p	CLIP-seq
MIRT1507664	hsa-miR-527	CLIP-seq
MIRT1507668	hsa-miR-552	CLIP-seq
MIRT2373233	hsa-miR-940	CLIP-seq
MIRT2397283	hsa-miR-1273e	CLIP-seq
MIRT2373224	hsa-miR-2964a-3p	CLIP-seq
MIRT2373225	hsa-miR-302f	CLIP-seq
MIRT2463884	hsa-miR-3668	CLIP-seq
MIRT2397283	hsa-miR-1273e	CLIP-seq
MIRT1507604	hsa-miR-2114	CLIP-seq
MIRT2666075	hsa-miR-217	CLIP-seq
MIRT2373223	hsa-miR-2682	CLIP-seq
MIRT2373224	hsa-miR-2964a-3p	CLIP-seq
MIRT2373225	hsa-miR-302f	CLIP-seq
MIRT1507612	hsa-miR-3120-5p	CLIP-seq
MIRT1507613	hsa-miR-3129-3p	CLIP-seq
MIRT2666076	hsa-miR-3143	CLIP-seq
MIRT1507615	hsa-miR-3163	CLIP-seq
MIRT2666077	hsa-miR-3545-3p	CLIP-seq
MIRT1507620	hsa-miR-3613-3p	CLIP-seq
MIRT1507621	hsa-miR-3622b-5p	CLIP-seq
MIRT1507626	hsa-miR-3664-5p	CLIP-seq
MIRT1507627	hsa-miR-3672	CLIP-seq
MIRT1507630	hsa-miR-371-5p	CLIP-seq
MIRT1507631	hsa-miR-371b-5p	CLIP-seq
MIRT1507637	hsa-miR-4253	CLIP-seq
MIRT2666078	hsa-miR-4282	CLIP-seq
MIRT2373228	hsa-miR-4423-3p	CLIP-seq
MIRT2373229	hsa-miR-449c	CLIP-seq
MIRT1507647	hsa-miR-4522	CLIP-seq
MIRT2666079	hsa-miR-4668-3p	CLIP-seq
MIRT2373231	hsa-miR-4722-5p	CLIP-seq
MIRT2152892	hsa-miR-4768-3p	CLIP-seq
MIRT1507666	hsa-miR-548c-3p	CLIP-seq
MIRT1507667	hsa-miR-548u	CLIP-seq
MIRT2666080	hsa-miR-579	CLIP-seq
MIRT1507675	hsa-miR-618	CLIP-seq
MIRT2373233	hsa-miR-940	CLIP-seq
MIRT2397283	hsa-miR-1273e	CLIP-seq
MIRT2373223	hsa-miR-2682	CLIP-seq
MIRT2373224	hsa-miR-2964a-3p	CLIP-seq
MIRT2373225	hsa-miR-302f	CLIP-seq
MIRT1507612	hsa-miR-3120-5p	CLIP-seq
MIRT1507615	hsa-miR-3163	CLIP-seq
MIRT1507620	hsa-miR-3613-3p	CLIP-seq
MIRT1507626	hsa-miR-3664-5p	CLIP-seq
MIRT1507627	hsa-miR-3672	CLIP-seq
MIRT1507630	hsa-miR-371-5p	CLIP-seq
MIRT1507631	hsa-miR-371b-5p	CLIP-seq
MIRT2666078	hsa-miR-4282	CLIP-seq
MIRT2373228	hsa-miR-4423-3p	CLIP-seq
MIRT2373229	hsa-miR-449c	CLIP-seq
MIRT1507647	hsa-miR-4522	CLIP-seq
MIRT2373231	hsa-miR-4722-5p	CLIP-seq
MIRT2152892	hsa-miR-4768-3p	CLIP-seq
MIRT1507666	hsa-miR-548c-3p	CLIP-seq
MIRT1507675	hsa-miR-618	CLIP-seq
MIRT2373233	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0008270	Function	Zinc ion binding	IEA

Other IDs

• MIM: 617059
• HGNC: 29313
• e!Ensembl: ENSG00000204186

Protein

• UniProt ID: Q9HCK1
• Protein name: DBF4-type zinc finger-containing protein 2
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07535	zf-DBF	3 → 36	DBF zinc finger	Domain

• Sequence:

  MQKRQGYCSYCRVQYNNLEQHLFSAQHRSLTRQSRRQICTSSLMERFLQDVLQHHPYHCQ
  ESSSTQDETHVNTGSSSEVVHLDDAFSEEEEEDEDKVEDEDATEERPSEVSEPIEELHSR
  PHKSQEGTQEVSVRPSVIQKLEKGQQQPLEFVHKIGASVRKCNLVDIGQATNNRSNLVRP
  PVICNAPASCLPESSNDRPVTANTTSLPPAAHLDSVSKCDPNKVEKYLEQPDGASRNPVP
  SSHVETTSFSYQKHKESNRKSLRMNSDKLVLWKDVKSQGKTLSAGLKFHERMGTKGSLRV
  KSPSKLAVNPNKTDMPSNKGIFEDTIAKNHEEFFSNMDCTQEEKHLVFNKTAFWEQKCSV
  SSEMKFDCISLQSASDQPQETAQDLSLWKEEQIDQEDNYESRGSEMSFDCSSSFHSLTDQ
  SKVSAKEVNLSKEVRTDVQYKNNKSYVSKISSDCDDILHLVTNQSQMIVKEISLQNARHI
  SLVDQSYESSSSETNFDCDASPQSTSDYPQQSVTEVNLPKEVHIGLVDKNYGSSSSEVSA
  DSVFPLQSVVDRPPVAVTETKLRKKAHTSLVDNYGSSCSETSFDCDVSLESVVDHPQLTV
  KGRNLKGRQVHLKHKKRKPSSAKAHLDCDVSLGTVADESQRAVEKINLLKEKNADLMDMN
  CESHGPEMGFQADAQLADQSQVAEIERQKVDVDLENKSVQSSRSSLSSDSPASLYHSAHD
  EPQEALDEVNLKELNIDMEVRSYDCSSSELTFDSDPPLLSVTEQSHLDAEGKERHIDLED
  ESCESDSSEITFDSDIPLYSVIDQPEVAVYEEETVDLESKSNESCVSEITFDSDIPLHSG
  NDHPEVAVKEVIQKEEYIHLERKNDEPSGSEISSDSHAPLHSVTNSPEVAVKKLNPQKEE
  QVHLENKENEPIDSEVSLDYNIIFHSVTGRSEDPIKEISLHTKEHMYLENKSVFETSLDS
  DVPLQAATHKPEVIVKETWLQREKHAEFQGRSTEFSGSKTSLDSGVPHYSVTEPQVAVNK
  INRKKQYVLENKNDKCSGSEIILDSNVPPQSMTDQPQLAFLKEKHVNLKDKNSKSGDSKI
  TFDSEQLQEAVKKIDQWKEEVIGLKNKINEPSTYKLIHHPDVSVQSVADQPKVAIKHVNL
  GNENHMYLEVKNSQYSCSEMNLDSGFLGQSIVNRPQITILEQEHIELEGKHNQCCGSEVS
  FDSDDPLQSVADRLRETVKEISLWKDEEVDTEDRRNEAKGFEIMYDSDVLQPVAGQPEEV
  VKEVSLWKEHVDLENKIVKPTDSRINFDSHEPLQSVTNKIPGANKEINLLREEHVCLDDK
  GYVPSDSEIIYVSNIPLQSVIKQPHILEEEHASLEDKSSNSYSPEESSDSNDSFQAAADE
  LQKPVKEINLWKEDHIYLEDKSYKLGDFDVSYASHIPVQFVTDQSSVPVKEINLQKKDHN
  DLENKNCEVCGSEIKCHSCVHLQSEVDQPQVSYKEADLQKEEHVVMEEKTDQPSDSEMMY
  DSDVPFQIVVNQFPGSVKETHLPKVVLVDLVPGDSDYEVISDDIPLQLVTDPPQLTVKDI
  SCINTECIDIEDKSCDFFGSEVRCNCKASTPSMTNQCKETFKIINRKKDYIILGEPSCQS
  CGSEMNFNVDASDQSMTYESQGPDEKMVKYIDSEDKSCGYNGSKGKFNLEDTSHRTTHRL
  QKAHKEASLRKDPRNAGLKGKSCQSSASAVDFGASSKSALHRRADKKKRSKLKHRDLEVS
  CEPDGFEMNFQCAPPLPSDTDQPQETVKKRHPCKKVSSDLKEKNHDSQSSSVLKVDSVRN
  LKKAKDVIEDNPDEPVLEALPHVPPSFVGKTWSQIMREDDIKINALVKEFREGRFHCYFD
  DDCETKKVSSKGKKKVTWADLQGKEDTAPTQAVSESDDIVCGISDIDDLSVALDKPCHRH
  PPAERPPKQKGRVASQCQTAKISHSTQTSCKNYPVMKRKIIRQEEDPPKSKCSRLQDDRK
  TKKKVKIGTVEFPASCTKVLKPMQPKALVCVLSSLNIKLKEGEGLPFPKMRHHSWDNDIR
  FICKYKRNIFDYYEPLIKQIVISPPLSVIVPEFERRNWVKIHFNRSNQNSSAGDNDADGQ
  GSASAPLMAVPARYGFNSHQGTSDSSLFLEESKVLHARELPKKRNFQLTFLNHDVVKISP
  KSVRNKLLESQSKKKIHGKRVTTSSNKLGFPKKVYKPIILQQKPRKASEKQSIWIRTKPS
  DIIRKYISKYSVFLRHRYQSRSAFLGRYLKKKKSVVSRLKKAKRTAKVLLNSSVPPAGAE
  ELSSAMANPPPKRPVRASCRVARRRKKTDESYHGRQKGPSTPVRAYDLRSSSCLQQRERM
  MTRLANKLRGNEVK

• Sequence length: 2354

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Lung carcinoma	Small cell carcinoma of lung	rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355, rs121912470, rs121913273, rs121913281, rs121913348, rs727503093, rs121913353, rs397516890, rs397516896, rs121913378, rs397516897, rs397516977, rs397516978, rs397516979, rs397516980, rs397516981, rs397516982, rs121913240, rs17851045, rs397517086, rs121913428, rs397517094, rs397517098, rs397517106, rs121913465, rs397517108, rs397517111, rs397517112, rs397517114, rs397517116, rs1554350366, rs397517127, rs397517200, rs397517202, rs121913283, rs121913370, rs121913357, rs727503106, rs121913238, rs727503108, rs397517040, rs397516976, rs1555618025, rs1057519729, rs1584238193	22941189