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PTMA (prothymosin alpha)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5757
Gene nameGene Name - the full gene name approved by the HGNC.
Prothymosin alpha
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
PTMA
SynonymsGene synonyms aliases
TMSA
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q37.1
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001343 hsa-miR-1-3p pSILAC 18668040
MIRT001343 hsa-miR-1-3p Immunoblot, Immunofluorescence, Immunoprecipitaion, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 22210864
MIRT001343 hsa-miR-1-3p Immunoblot, Immunofluorescence, Immunoprecipitaion, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 22210864
MIRT001343 hsa-miR-1-3p Luciferase reporter assay 22059741
MIRT001343 hsa-miR-1-3p Luciferase reporter assay 22059741
Transcription factors
Transcription factor Regulation Reference
ESR1 Repression 12149645
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 15607035, 16478804, 21044950, 25556234
GO:0005634 Component Nucleus IDA 8485135, 11897665
GO:0005654 Component Nucleoplasm IDA
GO:0005829 Component Cytosol IDA
GO:0006351 Process Transcription, DNA-templated TAS 10854063
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P06454
Protein name Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]
Protein function Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
PDB 2L9I , 2MNQ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03247 Prothymosin
2 110
Prothymosin/parathymosin family
Family
Sequence
Sequence length 111
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 10822126
Rhabdomyosarcoma Rhabdomyosarcoma rs137854557, rs121909224, rs63751466, rs11540652, rs28934874, rs104894229, rs104894230, rs267606708, rs80357867, rs276174889, rs80359011, rs80358556, rs80359391, rs80357989, rs886037650, rs886037651, rs201744589, rs587780067, rs587781462, rs587782144, rs55863639, rs768638173, rs864622639, rs875989784, rs876657714, rs878855246, rs199474742, rs879253942, rs886037721, rs1057519989, rs750380279, rs1131691211, rs1202793339, rs1567611375 16669873
Unknown
Disease name Disease term dbSNP ID References
Adenoma Adenoma, Adenoma, Basal Cell, Follicular adenoma, Adenoma, Microcystic, Adenoma, Monomorphic, Adenoma, Trabecular 10822126
Fatty liver Fatty Liver, Steatohepatitis 15885234
Lung neoplasms Lung Neoplasms 10822126
Papillary adenoma Papillary adenoma 10822126

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