Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57555 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Neuroligin 2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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NLGN2 |
SynonymsGene synonyms aliases
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- |
ChromosomeChromosome number
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17 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17p13.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided b |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q8NFZ4 |
Protein name |
Neuroligin-2 |
Protein function |
Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in s |
PDB |
5XEQ
,
8GS4
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00135 |
COesterase |
40 → 601 |
Carboxylesterase family |
Domain |
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Sequence |
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Sequence length |
835 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Schizophrenia |
Schizophrenia |
rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 |
21551456 |
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Uterine fibroids |
Uterine Fibroids |
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30194396 |
Plexiform leiomyoma |
Plexiform leiomyoma |
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30194396 |
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