COXFA4L2 (cytochrome c oxidase hypoxia associated subunit FA4L2)

Gene

• Entrez ID: 56901
• Gene name: Cytochrome c oxidase hypoxia associated subunit FA4L2
• Gene symbol: COXFA4L2
• Synonyms: MISTRH, NDUFA4L2, NUOMS
• Chromosome: 12
• Chromosome location: 12q13.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017521	hsa-miR-335-5p	Microarray	18185580
MIRT1178777	hsa-miR-1285	CLIP-seq
MIRT1178778	hsa-miR-1291	CLIP-seq
MIRT1178779	hsa-miR-1321	CLIP-seq
MIRT1178780	hsa-miR-2053	CLIP-seq
MIRT1178781	hsa-miR-3187-5p	CLIP-seq
MIRT1178782	hsa-miR-3619-3p	CLIP-seq
MIRT1178783	hsa-miR-3646	CLIP-seq
MIRT1178784	hsa-miR-3690	CLIP-seq
MIRT1178785	hsa-miR-4308	CLIP-seq
MIRT1178786	hsa-miR-4690-3p	CLIP-seq
MIRT1178787	hsa-miR-4728-5p	CLIP-seq
MIRT1178788	hsa-miR-4739	CLIP-seq
MIRT1178789	hsa-miR-4756-5p	CLIP-seq
MIRT1178790	hsa-miR-4776-5p	CLIP-seq
MIRT1178791	hsa-miR-612	CLIP-seq
MIRT1178792	hsa-miR-661	CLIP-seq
MIRT1178793	hsa-miR-939	CLIP-seq
MIRT1178777	hsa-miR-1285	CLIP-seq
MIRT1178778	hsa-miR-1291	CLIP-seq
MIRT1178781	hsa-miR-3187-5p	CLIP-seq
MIRT1178782	hsa-miR-3619-3p	CLIP-seq
MIRT1178784	hsa-miR-3690	CLIP-seq
MIRT1178785	hsa-miR-4308	CLIP-seq
MIRT1178790	hsa-miR-4776-5p	CLIP-seq
MIRT1178791	hsa-miR-612	CLIP-seq
MIRT1178792	hsa-miR-661	CLIP-seq
MIRT1178777	hsa-miR-1285	CLIP-seq
MIRT1178778	hsa-miR-1291	CLIP-seq
MIRT1178781	hsa-miR-3187-5p	CLIP-seq
MIRT1178782	hsa-miR-3619-3p	CLIP-seq
MIRT1178784	hsa-miR-3690	CLIP-seq
MIRT1178785	hsa-miR-4308	CLIP-seq
MIRT1178790	hsa-miR-4776-5p	CLIP-seq
MIRT1178791	hsa-miR-612	CLIP-seq
MIRT1178792	hsa-miR-661	CLIP-seq
MIRT1178777	hsa-miR-1285	CLIP-seq
MIRT1178778	hsa-miR-1291	CLIP-seq
MIRT1178781	hsa-miR-3187-5p	CLIP-seq
MIRT1178782	hsa-miR-3619-3p	CLIP-seq
MIRT1178784	hsa-miR-3690	CLIP-seq
MIRT1178785	hsa-miR-4308	CLIP-seq
MIRT1178790	hsa-miR-4776-5p	CLIP-seq
MIRT1178791	hsa-miR-612	CLIP-seq
MIRT1178792	hsa-miR-661	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004129	Function	Cytochrome-c oxidase activity	IBA	21873635
GO:0005751	Component	Mitochondrial respiratory chain complex IV	IBA	21873635
GO:0022900	Process	Electron transport chain	IEA
GO:1902600	Process	Proton transmembrane transport	IEA

Other IDs

• MIM: HGNC
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9NRX3
• Protein name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (NADH-ubiquinone oxidoreductase MLRQ subunit homolog) (NUOMS)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06522	B12D	16 → 84	NADH-ubiquinone reductase complex 1 MLRQ subunit	Family

• Sequence:

  MAGASLGARFYRQIKRHPGIIPMIGLICLGMGSAALYLLRLALRSPDVCWDRKNNPEPWN
  RLSPNDQYKFLAVSTDYKKLKKDRPDF

• Sequence length: 87

Pathways

KEGG:

Oxidative phosphorylation
Metabolic pathways
Thermogenesis
Retrograde endocannabinoid signaling
Non-alcoholic fatty liver disease
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Rheumatoid arthritis	Rheumatoid Arthritis	rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212	19192274