Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
5586 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Protein kinase N2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
PKN2 |
SynonymsGene synonyms aliases
|
PAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7 |
ChromosomeChromosome number
|
1 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
1p22.2 |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q16513 |
Protein name |
Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) |
Protein function |
PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migrati |
PDB |
4CRS
,
4RRV
,
6CCY
,
6GBE
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF02185 |
HR1 |
49 → 111 |
Hr1 repeat |
Family |
PF02185 |
HR1 |
137 → 204 |
Hr1 repeat |
Family |
PF02185 |
HR1 |
218 → 285 |
Hr1 repeat |
Family |
PF00069 |
Pkinase |
657 → 916 |
Protein kinase domain |
Domain |
PF00433 |
Pkinase_C |
937 → 979 |
Protein kinase C terminal domain |
Family |
|
Sequence |
|
Sequence length |
984 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
|