ATF7IP (activating transcription factor 7 interacting protein)

Gene

• Entrez ID: 55729
• Gene name: Activating transcription factor 7 interacting protein
• Gene symbol: ATF7IP
• Synonyms: AM, ATF-IP, ATF7IP1, MCAF, MCAF1, p621
• Chromosome: 12
• Chromosome location: 12p13.1
• Summary: ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT046291	hsa-miR-23b-3p	CLASH	23622248
MIRT044675	hsa-miR-320a	CLASH	23622248
MIRT037643	hsa-miR-744-5p	CLASH	23622248
MIRT036221	hsa-miR-320b	CLASH	23622248
MIRT568427	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT711688	hsa-miR-548p	HITS-CLIP	19536157
MIRT711687	hsa-miR-21-5p	HITS-CLIP	19536157
MIRT711686	hsa-miR-590-5p	HITS-CLIP	19536157
MIRT711685	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT711684	hsa-miR-3192-5p	HITS-CLIP	19536157
MIRT711683	hsa-miR-6878-5p	HITS-CLIP	19536157
MIRT711682	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT711681	hsa-miR-8085	HITS-CLIP	19536157
MIRT711680	hsa-miR-5579-3p	HITS-CLIP	19536157
MIRT711679	hsa-miR-33a-5p	HITS-CLIP	19536157
MIRT711678	hsa-miR-33b-5p	HITS-CLIP	19536157
MIRT711677	hsa-miR-30c-1-3p	HITS-CLIP	19536157
MIRT711676	hsa-miR-30c-2-3p	HITS-CLIP	19536157
MIRT711675	hsa-miR-6788-5p	HITS-CLIP	19536157
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT632058	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT632057	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT632056	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT632055	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT632054	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT632053	hsa-miR-3666	HITS-CLIP	23824327
MIRT632052	hsa-miR-4295	HITS-CLIP	23824327
MIRT632051	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT632050	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT632049	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT632048	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT632047	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT632046	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT632045	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT632044	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT632043	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568427	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT568426	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT568425	hsa-miR-16-1-3p	PAR-CLIP	20371350
MIRT568424	hsa-miR-4304	PAR-CLIP	20371350
MIRT568423	hsa-miR-198	PAR-CLIP	20371350
MIRT568422	hsa-miR-520a-5p	PAR-CLIP	20371350
MIRT568421	hsa-miR-525-5p	PAR-CLIP	20371350
MIRT568420	hsa-miR-3129-5p	PAR-CLIP	20371350
MIRT568419	hsa-miR-199b-3p	PAR-CLIP	20371350
MIRT568418	hsa-miR-199a-3p	PAR-CLIP	20371350
MIRT568417	hsa-miR-548ac	PAR-CLIP	20371350
MIRT568416	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT568415	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT568414	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT568413	hsa-miR-548z	PAR-CLIP	20371350
MIRT568412	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT568411	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT568410	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT568409	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT568408	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT568407	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT568406	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT568405	hsa-miR-548as-3p	PAR-CLIP	20371350
MIRT568404	hsa-miR-548l	PAR-CLIP	20371350
MIRT568403	hsa-miR-3130-5p	PAR-CLIP	20371350
MIRT568402	hsa-miR-4482-5p	PAR-CLIP	20371350
MIRT568401	hsa-miR-1244	PAR-CLIP	20371350
MIRT568400	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT568399	hsa-miR-3973	PAR-CLIP	20371350
MIRT568398	hsa-miR-520g-3p	PAR-CLIP	20371350
MIRT568397	hsa-miR-520h	PAR-CLIP	20371350
MIRT568396	hsa-miR-3155a	PAR-CLIP	20371350
MIRT568395	hsa-miR-3155b	PAR-CLIP	20371350
MIRT568394	hsa-miR-484	PAR-CLIP	20371350
MIRT568393	hsa-miR-607	PAR-CLIP	20371350
MIRT491012	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT491011	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT491010	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT491009	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT491008	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT491007	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT491006	hsa-miR-3145-3p	PAR-CLIP	23592263
MIRT491005	hsa-miR-548aw	PAR-CLIP	23592263
MIRT491004	hsa-miR-518a-5p	PAR-CLIP	23592263
MIRT491003	hsa-miR-527	PAR-CLIP	23592263
MIRT491002	hsa-miR-1303	PAR-CLIP	23592263
MIRT491001	hsa-miR-599	PAR-CLIP	23592263
MIRT568427	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT711688	hsa-miR-548p	HITS-CLIP	19536157
MIRT711687	hsa-miR-21-5p	HITS-CLIP	19536157
MIRT711686	hsa-miR-590-5p	HITS-CLIP	19536157
MIRT711685	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT711684	hsa-miR-3192-5p	HITS-CLIP	19536157
MIRT711683	hsa-miR-6878-5p	HITS-CLIP	19536157
MIRT711682	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT711681	hsa-miR-8085	HITS-CLIP	19536157
MIRT711680	hsa-miR-5579-3p	HITS-CLIP	19536157
MIRT711679	hsa-miR-33a-5p	HITS-CLIP	19536157
MIRT711678	hsa-miR-33b-5p	HITS-CLIP	19536157
MIRT711677	hsa-miR-30c-1-3p	HITS-CLIP	19536157
MIRT711676	hsa-miR-30c-2-3p	HITS-CLIP	19536157
MIRT711675	hsa-miR-6788-5p	HITS-CLIP	19536157
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT632058	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT632057	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT632056	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT632055	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT632054	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT632053	hsa-miR-3666	HITS-CLIP	23824327
MIRT632052	hsa-miR-4295	HITS-CLIP	23824327
MIRT632051	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT632050	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT632049	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT632048	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT632047	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT632046	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT632045	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT632044	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT632043	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568427	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT568426	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT568425	hsa-miR-16-1-3p	PAR-CLIP	20371350
MIRT568424	hsa-miR-4304	PAR-CLIP	20371350
MIRT568423	hsa-miR-198	PAR-CLIP	20371350
MIRT568422	hsa-miR-520a-5p	PAR-CLIP	20371350
MIRT568421	hsa-miR-525-5p	PAR-CLIP	20371350
MIRT568420	hsa-miR-3129-5p	PAR-CLIP	20371350
MIRT568419	hsa-miR-199b-3p	PAR-CLIP	20371350
MIRT568418	hsa-miR-199a-3p	PAR-CLIP	20371350
MIRT568417	hsa-miR-548ac	PAR-CLIP	20371350
MIRT568416	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT568415	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT568414	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT568413	hsa-miR-548z	PAR-CLIP	20371350
MIRT568412	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT568411	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT568410	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT568409	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT568408	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT568407	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT568406	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT568405	hsa-miR-548as-3p	PAR-CLIP	20371350
MIRT568404	hsa-miR-548l	PAR-CLIP	20371350
MIRT568403	hsa-miR-3130-5p	PAR-CLIP	20371350
MIRT568402	hsa-miR-4482-5p	PAR-CLIP	20371350
MIRT568401	hsa-miR-1244	PAR-CLIP	20371350
MIRT568400	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT568399	hsa-miR-3973	PAR-CLIP	20371350
MIRT568398	hsa-miR-520g-3p	PAR-CLIP	20371350
MIRT568397	hsa-miR-520h	PAR-CLIP	20371350
MIRT568396	hsa-miR-3155a	PAR-CLIP	20371350
MIRT568395	hsa-miR-3155b	PAR-CLIP	20371350
MIRT568394	hsa-miR-484	PAR-CLIP	20371350
MIRT568393	hsa-miR-607	PAR-CLIP	20371350
MIRT491012	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT491011	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT491010	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT491009	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT491008	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT491007	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT491006	hsa-miR-3145-3p	PAR-CLIP	23592263
MIRT491005	hsa-miR-548aw	PAR-CLIP	23592263
MIRT491004	hsa-miR-518a-5p	PAR-CLIP	23592263
MIRT491003	hsa-miR-527	PAR-CLIP	23592263
MIRT491002	hsa-miR-1303	PAR-CLIP	23592263
MIRT491001	hsa-miR-599	PAR-CLIP	23592263
MIRT804724	hsa-miR-142-3p	CLIP-seq
MIRT804725	hsa-miR-1587	CLIP-seq
MIRT804726	hsa-miR-1914	CLIP-seq
MIRT804727	hsa-miR-3074-5p	CLIP-seq
MIRT804728	hsa-miR-3124-3p	CLIP-seq
MIRT804729	hsa-miR-340	CLIP-seq
MIRT804730	hsa-miR-3977	CLIP-seq
MIRT804731	hsa-miR-4265	CLIP-seq
MIRT804732	hsa-miR-4280	CLIP-seq
MIRT804733	hsa-miR-4296	CLIP-seq
MIRT804734	hsa-miR-4322	CLIP-seq
MIRT804735	hsa-miR-4417	CLIP-seq
MIRT804736	hsa-miR-4492	CLIP-seq
MIRT804737	hsa-miR-4498	CLIP-seq
MIRT804738	hsa-miR-4656	CLIP-seq
MIRT804739	hsa-miR-4675	CLIP-seq
MIRT804740	hsa-miR-4682	CLIP-seq
MIRT804741	hsa-miR-4741	CLIP-seq
MIRT804742	hsa-miR-501-5p	CLIP-seq
MIRT804743	hsa-miR-762	CLIP-seq
MIRT804744	hsa-miR-935	CLIP-seq
MIRT804724	hsa-miR-142-3p	CLIP-seq
MIRT804729	hsa-miR-340	CLIP-seq
MIRT1937566	hsa-miR-3938	CLIP-seq
MIRT1937567	hsa-miR-3941	CLIP-seq
MIRT804730	hsa-miR-3977	CLIP-seq
MIRT804732	hsa-miR-4280	CLIP-seq
MIRT1937568	hsa-miR-4643	CLIP-seq
MIRT1937569	hsa-miR-466	CLIP-seq
MIRT1937570	hsa-miR-4672	CLIP-seq
MIRT1937571	hsa-miR-4789-3p	CLIP-seq
MIRT1937572	hsa-miR-4789-5p	CLIP-seq
MIRT1937573	hsa-miR-548g	CLIP-seq
MIRT804744	hsa-miR-935	CLIP-seq
MIRT804725	hsa-miR-1587	CLIP-seq
MIRT2177185	hsa-miR-3145-5p	CLIP-seq
MIRT2177186	hsa-miR-3148	CLIP-seq
MIRT2177187	hsa-miR-3591-3p	CLIP-seq
MIRT2177188	hsa-miR-3658	CLIP-seq
MIRT1937566	hsa-miR-3938	CLIP-seq
MIRT1937567	hsa-miR-3941	CLIP-seq
MIRT804731	hsa-miR-4265	CLIP-seq
MIRT804733	hsa-miR-4296	CLIP-seq
MIRT804734	hsa-miR-4322	CLIP-seq
MIRT804735	hsa-miR-4417	CLIP-seq
MIRT2177189	hsa-miR-4422	CLIP-seq
MIRT804736	hsa-miR-4492	CLIP-seq
MIRT804737	hsa-miR-4498	CLIP-seq
MIRT1937568	hsa-miR-4643	CLIP-seq
MIRT804738	hsa-miR-4656	CLIP-seq
MIRT1937569	hsa-miR-466	CLIP-seq
MIRT1937570	hsa-miR-4672	CLIP-seq
MIRT804739	hsa-miR-4675	CLIP-seq
MIRT804740	hsa-miR-4682	CLIP-seq
MIRT804741	hsa-miR-4741	CLIP-seq
MIRT1937571	hsa-miR-4789-3p	CLIP-seq
MIRT2177190	hsa-miR-513a-3p	CLIP-seq
MIRT1937573	hsa-miR-548g	CLIP-seq
MIRT2177191	hsa-miR-548o	CLIP-seq
MIRT2177192	hsa-miR-580	CLIP-seq
MIRT804743	hsa-miR-762	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0003714	Function	Transcription corepressor activity	IEA
GO:0005515	Function	Protein binding	IPI	12665582, 12812986, 26275350, 27732843
GO:0005634	Component	Nucleus	IDA	12665582
GO:0005634	Component	Nucleus	IMP	27732843
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005667	Component	Transcription regulator complex	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006306	Process	DNA methylation	IDA	12665582
GO:0016032	Process	Viral process	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0016887	Function	ATPase activity	IEA
GO:0031647	Process	Regulation of protein stability	IMP	27732843
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IDA	12665582
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IDA	12665582
GO:0045898	Process	Regulation of RNA polymerase II transcription preinitiation complex assembly	IDA	12665582
GO:0050821	Process	Protein stabilization	IMP	27732843
GO:0090309	Process	Positive regulation of DNA methylation-dependent heterochromatin assembly	IMP	27732843

Other IDs

• MIM: 613644
• HGNC: 20092
• e!Ensembl: ENSG00000171681

Protein

• UniProt ID: Q6VMQ6
• Protein name: Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621)
• Protein function: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-med
• PDB: 2RPQ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF16788	ATF7IP_BD	564 → 779	ATF-interacting protein binding domain	Family
  PF16794	fn3_4	1159 → 1260	Fibronectin-III type domain	Domain

• Sequence:

  MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLE
  NMDYIKDKEEVNGIEEICFDPEGSKAEWKETPCILSVNVKNKQDDDLNCEPLSPHNITPE
  PVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAP
  SGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLA
  SGAPASTDPASDDLASGDLSSSELASDDLATGELASDELTSESTFDRTFEPKSVPVCEPV
  PEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTIC
  SDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKS
  ENILENTDSMETDEIIPILEKLAPSEDELTCFSKTSLLPIDETNPDLEEKMESSFGSPSK
  QESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHE
  DDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQ
  WLLEEKLCALQCAVFDKTLAELKTRVEKIECNKRHKTVLTELQAKIARLTKRFEAAKEDL
  KKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNTV
  SSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQP
  LPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVEFISVQSPPTVSGLTKNPVSLPSLPN
  PTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSP
  STNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATG
  SDSSGVIDLTMDDEESGASQDPKKLNHTPVSTMSSSQPVSRPLQPIQPAPPLQPSGVPTS
  GPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTV
  MQAPAVRQVNPQNSVTVRVPQTTTYVVNNGLTLGSTGPQLTVHHRPPQVHTEPPRPVHPA
  PLPEAPQPQRLPPEAASTSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYA
  YHEEPSATVPSQWKKIGEVKALPLPMACTLTQFVSGSKYYFAVRAKDIYGRFGPFCDPQS
  TDVISSTQSS

• Sequence length: 1270

Pathways

Reactome:

PKMTs methylate histone lysines

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Neoplasm	Neoplasms, Germ Cell and Embryonal, Neoplasms, Embryonal and Mixed	rs137854562, rs137854565, rs137854568, rs137854574, rs121434220, rs121909218, rs121909222, rs587776667, rs606231169, rs587776701, rs121913388, rs137852578, rs137852216, rs121912651, rs28934575, rs28934571, rs121912654, rs11540652, rs28934573, rs28934576, rs28934578, rs121912667, rs104893810, rs121913530, rs121913301, rs79184941, rs121908595, rs11554290, rs121434596, rs121913364, rs121434592, rs121913502, rs11554273, rs121913495, rs121913479, rs121913412, rs121913407, rs80338964, rs377767360, rs387906650, rs121913272, rs63750393, rs587776935, rs121913250, rs121913237, rs397516436, rs121913343, rs397516439, rs397516981, rs121913240, rs121913529, rs121913428, rs121913465, rs397517199, rs397517201, rs45446594, rs45481400, rs80358042, rs146650273, rs63750087, rs398123117, rs201744589, rs587778833, rs587778867, rs587778850, rs587778825, rs587776783, rs587780070, rs587780071, rs587780073, rs587777476, rs587781255, rs587781288, rs587781392, rs587781558, rs80358870, rs587781694, rs587781807, rs587782018, rs587782206, rs121913344, rs587782529, rs587782664, rs587782682, rs587782705, rs121913500, rs121913291, rs587783697, rs587783690, rs587783502, rs193920774, rs724159946, rs730880472, rs564652222, rs730882029, rs730882005, rs730882025, rs730882019, rs869025192, rs768922431, rs786203485, rs786202918, rs398123329, rs786201059, rs121912657, rs786201090, rs786204910, rs786204853, rs121913293, rs121913332, rs797044942, rs121913333, rs863224491, rs863224451, rs863224499, rs760043106, rs863225332, rs864622636, rs864622451, rs779707422, rs879255270, rs875989848, rs876661244, rs876660754, rs746235533, rs876659384, rs587778720, rs483352697, rs876658694, rs121913331, rs55863639, rs786203650, rs879254171, rs80359365, rs886040960, rs886042002, rs886041779, rs1057516620, rs1057517302, rs1057517544, rs1057517992, rs1057518134, rs985033810, rs1057517840, rs587777613, rs147001633, rs377577594, rs121913499, rs121909224, rs1057519724, rs1057519729, rs121913503, rs1057519742, rs121913294, rs121913538, rs121913287, rs121913284, rs74535574, rs1057519757, rs397516790, rs121913285, rs121913387, rs121913236, rs1057519893, rs1057519906, rs1057519929, rs772110575, rs1057519941, rs786202962, rs764146326, rs1057519989, rs121912656, rs1057519992, rs866775781, rs1057519996, rs765848205, rs138729528, rs786201057, rs864622237, rs1057520672, rs1060500766, rs587781702, rs866380588, rs11540654, rs770776262, rs1057519984, rs121913321, rs1064793022, rs1064794276, rs112431538, rs1064794311, rs1064794618, rs1064796632, rs750318549, rs1554897889, rs1554900675, rs1114167568, rs587783031, rs1114167621, rs1114167629, rs1114167657, rs1131690863, rs11575996, rs1131691039, rs1131691026, rs1131690921, rs1131691082, rs863225313, rs1554085846, rs1553647989, rs1554898074, rs764735889, rs553257776, rs1554898067, rs1555615472, rs1060500352, rs1555526131, rs1057519990, rs1270783041, rs1019340046, rs1057523347, rs1553332772, rs1555525429, rs1060500345, rs1554730670, rs1555526469, rs11575997, rs1554069710, rs1555610903, rs1565400045, rs1565486028, rs1569061768, rs1114167577, rs1561588104, rs751448371, rs1564568473, rs1567556930, rs1567555934, rs1559587104, rs1569293373, rs1568498107, rs141798398, rs1597359215, rs757274881, rs1567556123, rs1555525367, rs1202793339, rs1568504941, rs1587330312, rs1060501207, rs1589596415, rs1595314951, rs1598173737, rs1597375294, rs1567555445, rs1595331264, rs1593060859, rs1859977029, rs1217977493, rs1961431691, rs2073243450, rs1724674149, rs1820531050	20543847
Lymphoblastic leukemia	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	rs387906351, rs104894562, rs398122513, rs398122840, rs398123063, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699, rs1597567692, rs1597567985, rs1438890364, rs1288977950, rs1597552140, rs1597566356, rs1597566726, rs1597568117, rs2069719445, rs2069729948, rs2070018439, rs745708044, rs1169577591	24413735
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	31374203

Unknown
Disease name	Disease term	dbSNP ID	References
Embryonal neoplasm	Embryonal Neoplasm		20543847
Tumor	Germ cell tumor		20543847
Malignant neoplasm of testis	Malignant neoplasm of testis		20543847
Malignant testicular germ cell tumor	Malignant Testicular Germ Cell Tumor		20543847
Tumor of rete testis	Tumor of Rete Testis		20543847
Testicular neoplasms	Testicular Neoplasms		20543847, 23666240
Testicular germ cell tumor	Testicular Germ Cell Tumor		23666240, 28604728, 28604732