Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55568 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Polypeptide N-acetylgalactosaminyltransferase 10 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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GALNT10 |
SynonymsGene synonyms aliases
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GALNACT10, PPGALNACT10, PPGANTASE10 |
ChromosomeChromosome number
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5 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q33.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine re |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q86SR1 |
Protein name |
Polypeptide N-acetylgalactosaminyltransferase 10 (EC 2.4.1.41) (Polypeptide GalNAc transferase 10) (GalNAc-T10) (pp-GaNTase 10) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10) |
Protein function |
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. |
PDB |
2D7I
,
2D7R
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Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00535 |
Glycos_transf_2 |
148 → 333 |
Glycosyl transferase family 2 |
Family |
PF00652 |
Ricin_B_lectin |
459 → 587 |
Ricin-type beta-trefoil lectin domain |
Domain |
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Sequence |
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Sequence length |
603 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Schizophrenia |
Schizophrenia |
rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 |
25056061, 31268507, 30285260, 29503163, 28991256, 26198764, 28540026, 31374203, 29483656 |
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Development disorder |
Child Development Disorders, Pervasive |
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28540026 |
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