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STYK1 (serine/threonine/tyrosine kinase 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55359
Gene nameGene Name - the full gene name approved by the HGNC.
Serine/threonine/tyrosine kinase 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
STYK1
SynonymsGene synonyms aliases
NOK, SuRTK106
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.2
SummarySummary of gene provided in NCBI Entrez Gene.
Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT712045 hsa-miR-2116-5p HITS-CLIP 19536157
MIRT712044 hsa-miR-22-5p HITS-CLIP 19536157
MIRT712043 hsa-miR-4666a-5p HITS-CLIP 19536157
MIRT712042 hsa-miR-4677-5p HITS-CLIP 19536157
MIRT270128 hsa-miR-653-5p HITS-CLIP 19536157
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004713 Function Protein tyrosine kinase activity IBA 21873635
GO:0004715 Function Non-membrane spanning protein tyrosine kinase activity IBA 21873635
GO:0005102 Function Signaling receptor binding IBA 21873635
GO:0005515 Function Protein binding IPI 23010592
GO:0005524 Function ATP binding IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q6J9G0
Protein name Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)
Protein function Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase an
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07714 PK_Tyr_Ser-Thr
114 380
Protein tyrosine and serine/threonine kinase
Domain
Sequence
Sequence length 422
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Glioblastoma Glioblastoma Multiforme rs121913500, rs886042842, rs1555138291, rs1558518449, rs1567176006, rs1558650888

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