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RAVER2 (ribonucleoprotein, PTB binding 2)

Gene

55225

Ribonucleoprotein, PTB binding 2

RAVER2

1p31.3

Show/Hide all(265)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002305	hsa-let-7a-5p	Immunoprecipitaion, Luciferase reporter assay, Western blot	17637574
MIRT002306	hsa-miR-99a-5p	Immunoprecipitaion, Luciferase reporter assay, Western blot	17637574
MIRT002307	hsa-miR-99b-5p	Immunoprecipitaion, Luciferase reporter assay, Western blot	17637574
MIRT001827	hsa-miR-124-3p	Microarray, qRT-PCR	16549876
MIRT001827	hsa-miR-124-3p	qRT-PCR;Other	16549876
MIRT045678	hsa-miR-149-5p	CLASH	23622248
MIRT040013	hsa-miR-615-3p	CLASH	23622248
MIRT534755	hsa-miR-1267	PAR-CLIP	20371350
MIRT534754	hsa-miR-367-5p	PAR-CLIP	20371350
MIRT534753	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT534752	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT534751	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT534750	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT534749	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT534748	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT534747	hsa-miR-4684-3p	PAR-CLIP	20371350
MIRT534746	hsa-miR-197-3p	PAR-CLIP	20371350
MIRT534745	hsa-miR-548aw	PAR-CLIP	20371350
MIRT534744	hsa-miR-518a-5p	PAR-CLIP	20371350
MIRT534743	hsa-miR-527	PAR-CLIP	20371350
MIRT534755	hsa-miR-1267	PAR-CLIP	22012620
MIRT534754	hsa-miR-367-5p	PAR-CLIP	22012620
MIRT534753	hsa-miR-3124-3p	PAR-CLIP	22012620
MIRT534752	hsa-miR-548aj-5p	PAR-CLIP	22012620
MIRT534751	hsa-miR-548f-5p	PAR-CLIP	22012620
MIRT534750	hsa-miR-548g-5p	PAR-CLIP	22012620
MIRT534749	hsa-miR-548x-5p	PAR-CLIP	22012620
MIRT534748	hsa-miR-1468-3p	PAR-CLIP	22012620
MIRT534747	hsa-miR-4684-3p	PAR-CLIP	22012620
MIRT534746	hsa-miR-197-3p	PAR-CLIP	22012620
MIRT534745	hsa-miR-548aw	PAR-CLIP	22012620
MIRT534744	hsa-miR-518a-5p	PAR-CLIP	22012620
MIRT534743	hsa-miR-527	PAR-CLIP	22012620
MIRT534748	hsa-miR-1468-3p	PAR-CLIP	27292025
MIRT534746	hsa-miR-197-3p	PAR-CLIP	27292025
MIRT534753	hsa-miR-3124-3p	PAR-CLIP	27292025
MIRT534747	hsa-miR-4684-3p	PAR-CLIP	27292025
MIRT534744	hsa-miR-518a-5p	PAR-CLIP	27292025
MIRT534743	hsa-miR-527	PAR-CLIP	27292025
MIRT534752	hsa-miR-548aj-5p	PAR-CLIP	27292025
MIRT534745	hsa-miR-548aw	PAR-CLIP	27292025
MIRT534751	hsa-miR-548f-5p	PAR-CLIP	27292025
MIRT534750	hsa-miR-548g-5p	PAR-CLIP	27292025
MIRT534749	hsa-miR-548x-5p	PAR-CLIP	27292025
MIRT534755	hsa-miR-1267	PAR-CLIP	20371350
MIRT534754	hsa-miR-367-5p	PAR-CLIP	20371350
MIRT534753	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT534752	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT534751	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT534750	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT534749	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT534748	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT534747	hsa-miR-4684-3p	PAR-CLIP	20371350
MIRT534746	hsa-miR-197-3p	PAR-CLIP	20371350
MIRT534745	hsa-miR-548aw	PAR-CLIP	20371350
MIRT534744	hsa-miR-518a-5p	PAR-CLIP	20371350
MIRT534743	hsa-miR-527	PAR-CLIP	20371350
MIRT534755	hsa-miR-1267	PAR-CLIP	22012620
MIRT534754	hsa-miR-367-5p	PAR-CLIP	22012620
MIRT534753	hsa-miR-3124-3p	PAR-CLIP	22012620
MIRT534752	hsa-miR-548aj-5p	PAR-CLIP	22012620
MIRT534751	hsa-miR-548f-5p	PAR-CLIP	22012620
MIRT534750	hsa-miR-548g-5p	PAR-CLIP	22012620
MIRT534749	hsa-miR-548x-5p	PAR-CLIP	22012620
MIRT534748	hsa-miR-1468-3p	PAR-CLIP	22012620
MIRT534747	hsa-miR-4684-3p	PAR-CLIP	22012620
MIRT534746	hsa-miR-197-3p	PAR-CLIP	22012620
MIRT534745	hsa-miR-548aw	PAR-CLIP	22012620
MIRT534744	hsa-miR-518a-5p	PAR-CLIP	22012620
MIRT534743	hsa-miR-527	PAR-CLIP	22012620
MIRT1293217	hsa-let-7a	CLIP-seq
MIRT1293218	hsa-let-7b	CLIP-seq
MIRT1293219	hsa-let-7c	CLIP-seq
MIRT1293220	hsa-let-7d	CLIP-seq
MIRT1293221	hsa-let-7e	CLIP-seq
MIRT1293222	hsa-let-7f	CLIP-seq
MIRT1293223	hsa-let-7g	CLIP-seq
MIRT1293224	hsa-let-7i	CLIP-seq
MIRT1293225	hsa-miR-100	CLIP-seq
MIRT1293226	hsa-miR-1237	CLIP-seq
MIRT1293227	hsa-miR-1238	CLIP-seq
MIRT1293228	hsa-miR-1248	CLIP-seq
MIRT1293229	hsa-miR-1273d	CLIP-seq
MIRT1293230	hsa-miR-1293	CLIP-seq
MIRT1293231	hsa-miR-1294	CLIP-seq
MIRT1293232	hsa-miR-135a	CLIP-seq
MIRT1293233	hsa-miR-135b	CLIP-seq
MIRT1293234	hsa-miR-1909	CLIP-seq
MIRT1293235	hsa-miR-1915	CLIP-seq
MIRT1293236	hsa-miR-202	CLIP-seq
MIRT1293237	hsa-miR-21	CLIP-seq
MIRT1293238	hsa-miR-2861	CLIP-seq
MIRT1293239	hsa-miR-3138	CLIP-seq
MIRT1293240	hsa-miR-3148	CLIP-seq
MIRT1293241	hsa-miR-3153	CLIP-seq
MIRT1293242	hsa-miR-3179	CLIP-seq
MIRT1293243	hsa-miR-3192	CLIP-seq
MIRT1293244	hsa-miR-3201	CLIP-seq
MIRT1293245	hsa-miR-3202	CLIP-seq
MIRT1293246	hsa-miR-345	CLIP-seq
MIRT1293247	hsa-miR-3529	CLIP-seq
MIRT1293248	hsa-miR-3656	CLIP-seq
MIRT1293249	hsa-miR-3681	CLIP-seq
MIRT1293250	hsa-miR-370	CLIP-seq
MIRT1293251	hsa-miR-371b-5p	CLIP-seq
MIRT1293252	hsa-miR-379	CLIP-seq
MIRT1293253	hsa-miR-3909	CLIP-seq
MIRT1293254	hsa-miR-3918	CLIP-seq
MIRT1293255	hsa-miR-3936	CLIP-seq
MIRT1293256	hsa-miR-4314	CLIP-seq
MIRT1293257	hsa-miR-4451	CLIP-seq
MIRT1293258	hsa-miR-4458	CLIP-seq
MIRT1293259	hsa-miR-4476	CLIP-seq
MIRT1293260	hsa-miR-4483	CLIP-seq
MIRT1293261	hsa-miR-4491	CLIP-seq
MIRT1293262	hsa-miR-4500	CLIP-seq
MIRT1293263	hsa-miR-4512	CLIP-seq
MIRT1293264	hsa-miR-4522	CLIP-seq
MIRT1293265	hsa-miR-4536	CLIP-seq
MIRT1293266	hsa-miR-4646-5p	CLIP-seq
MIRT1293267	hsa-miR-4650-3p	CLIP-seq
MIRT1293268	hsa-miR-4651	CLIP-seq
MIRT1293269	hsa-miR-4657	CLIP-seq
MIRT1293270	hsa-miR-4668-5p	CLIP-seq
MIRT1293271	hsa-miR-4691-5p	CLIP-seq
MIRT1293272	hsa-miR-4693-3p	CLIP-seq
MIRT1293273	hsa-miR-4698	CLIP-seq
MIRT1293274	hsa-miR-4703-3p	CLIP-seq
MIRT1293275	hsa-miR-4723-5p	CLIP-seq
MIRT1293276	hsa-miR-4776-3p	CLIP-seq
MIRT1293277	hsa-miR-4791	CLIP-seq
MIRT1293278	hsa-miR-4800-5p	CLIP-seq
MIRT1293279	hsa-miR-519a	CLIP-seq
MIRT1293280	hsa-miR-519b-3p	CLIP-seq
MIRT1293281	hsa-miR-519c-3p	CLIP-seq
MIRT1293282	hsa-miR-522	CLIP-seq
MIRT1293283	hsa-miR-548ac	CLIP-seq
MIRT1293284	hsa-miR-548d-3p	CLIP-seq
MIRT1293285	hsa-miR-548z	CLIP-seq
MIRT1293286	hsa-miR-590-5p	CLIP-seq
MIRT1293287	hsa-miR-608	CLIP-seq
MIRT1293288	hsa-miR-711	CLIP-seq
MIRT1293289	hsa-miR-98	CLIP-seq
MIRT1293290	hsa-miR-99a	CLIP-seq
MIRT1293291	hsa-miR-99b	CLIP-seq
MIRT2087086	hsa-miR-1268	CLIP-seq
MIRT2087087	hsa-miR-1268b	CLIP-seq
MIRT2087088	hsa-miR-138	CLIP-seq
MIRT2087089	hsa-miR-2278	CLIP-seq
MIRT2087090	hsa-miR-3074-5p	CLIP-seq
MIRT2087091	hsa-miR-3136-5p	CLIP-seq
MIRT2087092	hsa-miR-3650	CLIP-seq
MIRT2087093	hsa-miR-3652	CLIP-seq
MIRT2087094	hsa-miR-3659	CLIP-seq
MIRT2087095	hsa-miR-3668	CLIP-seq
MIRT2087096	hsa-miR-369-3p	CLIP-seq
MIRT1293250	hsa-miR-370	CLIP-seq
MIRT2087097	hsa-miR-374a	CLIP-seq
MIRT2087098	hsa-miR-374b	CLIP-seq
MIRT2087099	hsa-miR-4265	CLIP-seq
MIRT2087100	hsa-miR-4296	CLIP-seq
MIRT2087101	hsa-miR-4322	CLIP-seq
MIRT2087102	hsa-miR-4417	CLIP-seq
MIRT2087103	hsa-miR-4430	CLIP-seq
MIRT2087104	hsa-miR-4439	CLIP-seq
MIRT2087105	hsa-miR-4505	CLIP-seq
MIRT2087106	hsa-miR-450b-5p	CLIP-seq
MIRT2087107	hsa-miR-4513	CLIP-seq
MIRT2087108	hsa-miR-4639-3p	CLIP-seq
MIRT2087109	hsa-miR-4655-5p	CLIP-seq
MIRT2087110	hsa-miR-4658	CLIP-seq
MIRT2087111	hsa-miR-4732-5p	CLIP-seq
MIRT2087112	hsa-miR-4758-5p	CLIP-seq
MIRT2087113	hsa-miR-4775	CLIP-seq
MIRT2087114	hsa-miR-4778-3p	CLIP-seq
MIRT2087115	hsa-miR-495	CLIP-seq
MIRT2087116	hsa-miR-507	CLIP-seq
MIRT2087117	hsa-miR-557	CLIP-seq
MIRT2087118	hsa-miR-574-5p	CLIP-seq
MIRT2087119	hsa-miR-585	CLIP-seq
MIRT2087120	hsa-miR-590-3p	CLIP-seq
MIRT2087121	hsa-miR-629	CLIP-seq
MIRT2087122	hsa-miR-648	CLIP-seq
MIRT2087123	hsa-miR-668	CLIP-seq
MIRT2087124	hsa-miR-943	CLIP-seq
MIRT1293225	hsa-miR-100	CLIP-seq
MIRT2087086	hsa-miR-1268	CLIP-seq
MIRT2087087	hsa-miR-1268b	CLIP-seq
MIRT2311924	hsa-miR-134	CLIP-seq
MIRT2087088	hsa-miR-138	CLIP-seq
MIRT2311925	hsa-miR-1913	CLIP-seq
MIRT2311926	hsa-miR-197	CLIP-seq
MIRT2311927	hsa-miR-200b	CLIP-seq
MIRT2311928	hsa-miR-200c	CLIP-seq
MIRT2311929	hsa-miR-208a	CLIP-seq
MIRT2311930	hsa-miR-208b	CLIP-seq
MIRT2311931	hsa-miR-27a	CLIP-seq
MIRT2311932	hsa-miR-27b	CLIP-seq
MIRT2311933	hsa-miR-30a	CLIP-seq
MIRT2311934	hsa-miR-30b	CLIP-seq
MIRT2311935	hsa-miR-30c	CLIP-seq
MIRT2311936	hsa-miR-30d	CLIP-seq
MIRT2311937	hsa-miR-30e	CLIP-seq
MIRT2311938	hsa-miR-3118	CLIP-seq
MIRT1293241	hsa-miR-3153	CLIP-seq
MIRT2311939	hsa-miR-3164	CLIP-seq
MIRT2311940	hsa-miR-3189-5p	CLIP-seq
MIRT1293243	hsa-miR-3192	CLIP-seq
MIRT1293244	hsa-miR-3201	CLIP-seq
MIRT2311941	hsa-miR-324-3p	CLIP-seq
MIRT2311942	hsa-miR-340	CLIP-seq
MIRT2087092	hsa-miR-3650	CLIP-seq
MIRT2087093	hsa-miR-3652	CLIP-seq
MIRT2087099	hsa-miR-4265	CLIP-seq
MIRT2311943	hsa-miR-4277	CLIP-seq
MIRT2311944	hsa-miR-429	CLIP-seq
MIRT2087100	hsa-miR-4296	CLIP-seq
MIRT1293256	hsa-miR-4314	CLIP-seq
MIRT2311945	hsa-miR-4318	CLIP-seq
MIRT2087101	hsa-miR-4322	CLIP-seq
MIRT2087102	hsa-miR-4417	CLIP-seq
MIRT2087103	hsa-miR-4430	CLIP-seq
MIRT2311946	hsa-miR-4432	CLIP-seq
MIRT2311947	hsa-miR-4474-5p	CLIP-seq
MIRT2311948	hsa-miR-4495	CLIP-seq
MIRT2087105	hsa-miR-4505	CLIP-seq
MIRT2087106	hsa-miR-450b-5p	CLIP-seq
MIRT2087108	hsa-miR-4639-3p	CLIP-seq
MIRT1293266	hsa-miR-4646-5p	CLIP-seq
MIRT2087109	hsa-miR-4655-5p	CLIP-seq
MIRT1293270	hsa-miR-4668-5p	CLIP-seq
MIRT2311949	hsa-miR-4693-5p	CLIP-seq
MIRT2311950	hsa-miR-4727-5p	CLIP-seq
MIRT2311951	hsa-miR-4747-3p	CLIP-seq
MIRT2087113	hsa-miR-4775	CLIP-seq
MIRT2311952	hsa-miR-4777-5p	CLIP-seq
MIRT1293277	hsa-miR-4791	CLIP-seq
MIRT2311953	hsa-miR-499-5p	CLIP-seq
MIRT2087116	hsa-miR-507	CLIP-seq
MIRT2311954	hsa-miR-5096	CLIP-seq
MIRT2311955	hsa-miR-513a-5p	CLIP-seq
MIRT2311956	hsa-miR-518d-5p	CLIP-seq
MIRT2311957	hsa-miR-519b-5p	CLIP-seq
MIRT2311958	hsa-miR-519c-5p	CLIP-seq
MIRT2311959	hsa-miR-520c-5p	CLIP-seq
MIRT1293282	hsa-miR-522	CLIP-seq
MIRT2311960	hsa-miR-526a	CLIP-seq
MIRT2311961	hsa-miR-548c-3p	CLIP-seq
MIRT2311962	hsa-miR-554	CLIP-seq
MIRT2087117	hsa-miR-557	CLIP-seq
MIRT2087119	hsa-miR-585	CLIP-seq
MIRT2087120	hsa-miR-590-3p	CLIP-seq
MIRT2087121	hsa-miR-629	CLIP-seq
MIRT2087123	hsa-miR-668	CLIP-seq
MIRT2311963	hsa-miR-892a	CLIP-seq
MIRT2311964	hsa-miR-938	CLIP-seq
MIRT1293290	hsa-miR-99a	CLIP-seq
MIRT1293291	hsa-miR-99b	CLIP-seq
MIRT2608354	hsa-miR-129-5p	CLIP-seq
MIRT2608355	hsa-miR-1301	CLIP-seq
MIRT2087106	hsa-miR-450b-5p	CLIP-seq
MIRT2608356	hsa-miR-4660	CLIP-seq
MIRT2608357	hsa-miR-5047	CLIP-seq
MIRT2087116	hsa-miR-507	CLIP-seq
MIRT2087117	hsa-miR-557	CLIP-seq

Show/Hide all(5)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IBA	21873635
GO:0003676	Function	Nucleic acid binding	IBA	21873635
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	IEA

MIM	HGNC	e!Ensembl
609953	25577	ENSG00000162437

Protein

UniProt ID

Q9HCJ3

Protein name

Ribonucleoprotein PTB-binding 2 (Protein raver-2)

Protein function

May bind single-stranded nucleic acids.

PDB

1WG1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	71 → 134	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF00076	RRM_1	144 → 213	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF00076	RRM_1	233 → 303	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

Sequence

MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR
MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI
QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG
HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS
DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS
KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ
LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQSSVMGNTSNLFLQNLSHIPLAQQ
QLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTT
ITAGMGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSL
LVGHHKQQQSQPKGTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPA
SKTTLHKTGIASSILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISA
PEGGSVECVDQHSQGTGAYYMETYLKKKRVY

Sequence length

691

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (2)

Causal
Disease name	Disease term	dbSNP ID	References
Glioblastoma	Glioblastoma, Glioblastoma Multiforme	rs121913500, rs886042842, rs1555138291, rs1558518449, rs1567176006, rs1558650888	28346443
Glioma	Glioma	rs121909219, rs121909224, rs587776667, rs587776671, rs121909239, rs121909241, rs28933368, rs121913500, rs55863639, rs786201995, rs786202517, rs786201044, rs398123317, rs1057518425, rs121913499, rs1060500122, rs781647403, rs1060500126, rs1554897889, rs1114167629, rs1114167656, rs587782603, rs1554893824, rs1554900615, rs1564568660, rs786204900, rs762518389, rs1339631701	28346443, 29743610

Show/Hide Unknown Diseases (1)

Unknown
Disease name	Disease term	dbSNP ID	References
Central nervous system neoplasms	Central Nervous System Neoplasms		28346443

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