Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
55167 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
MSL complex subunit 2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
MSL2 |
SynonymsGene synonyms aliases
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KBHS, MSL-2, MSL2L1, RNF184 |
ChromosomeChromosome number
|
3 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
3q22.3 |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q9HCI7 |
Protein name |
E3 ubiquitin-protein ligase MSL2 (EC 2.3.2.27) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184) |
Protein function |
Non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction (PubMed:16543150, PubM |
PDB |
4B7Y
,
4B86
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF16685 |
zf-RING_10 |
42 → 111 |
zinc RING finger of MSL2 |
Domain |
PF16682 |
MSL2-CXC |
455 → 509 |
CXC domain of E3 ubiquitin-protein ligase MSL2 |
Domain |
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Sequence |
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Sequence length |
577 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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