Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
55048 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
VPS37C subunit of ESCRT-I |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
VPS37C |
SynonymsGene synonyms aliases
|
- |
ChromosomeChromosome number
|
11 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
11q12.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
A5D8V6 |
Protein name |
Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C) |
Protein function |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:155095 |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF07200 |
Mod_r |
5 → 150 |
Modifier of rudimentary (Mod(r)) protein |
Domain |
|
Sequence |
|
Sequence length |
355 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
|