Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
55014 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Syntaxin 17 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
STX17 |
SynonymsGene synonyms aliases
|
- |
ChromosomeChromosome number
|
9 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
9q31.1 |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0000149 |
Function |
SNARE binding |
IBA |
21873635 |
GO:0000149 |
Function |
SNARE binding |
IDA |
23217709 |
GO:0000421 |
Component |
Autophagosome membrane |
IBA |
21873635 |
GO:0000421 |
Component |
Autophagosome membrane |
IDA |
23217709, 26416964, 28306502 |
GO:0005484 |
Function |
SNAP receptor activity |
IBA |
21873635 |
GO:0005484 |
Function |
SNAP receptor activity |
IMP |
23217709 |
GO:0005515 |
Function |
Protein binding |
IPI |
23217709, 24554770, 25419848, 25686604, 28013294, 28306502, 29549094, 30704899, 31806350 |
GO:0005739 |
Component |
Mitochondrion |
IDA |
23217709 |
GO:0005739 |
Component |
Mitochondrion |
IDA |
10930465 |
GO:0005765 |
Component |
Lysosomal membrane |
IDA |
10930465 |
GO:0005776 |
Component |
Autophagosome |
IDA |
25686604 |
GO:0005789 |
Component |
Endoplasmic reticulum membrane |
IDA |
23217709 |
GO:0005791 |
Component |
Rough endoplasmic reticulum |
IDA |
10930465 |
GO:0005793 |
Component |
Endoplasmic reticulum-Golgi intermediate compartment |
IDA |
23006999 |
GO:0005829 |
Component |
Cytosol |
ISS |
|
GO:0005886 |
Component |
Plasma membrane |
IBA |
21873635 |
GO:0006886 |
Process |
Intracellular protein transport |
IBA |
21873635 |
GO:0006887 |
Process |
Exocytosis |
IBA |
21873635 |
GO:0006888 |
Process |
Endoplasmic reticulum to Golgi vesicle-mediated transport |
IMP |
21545355 |
GO:0006906 |
Process |
Vesicle fusion |
IBA |
21873635 |
GO:0007030 |
Process |
Golgi organization |
IMP |
21545355 |
GO:0012505 |
Component |
Endomembrane system |
IBA |
21873635 |
GO:0012507 |
Component |
ER to Golgi transport vesicle membrane |
IEA |
|
GO:0016021 |
Component |
Integral component of membrane |
IBA |
21873635 |
GO:0016240 |
Process |
Autophagosome membrane docking |
IDA |
25686604 |
GO:0019901 |
Function |
Protein kinase binding |
IEA |
|
GO:0019903 |
Function |
Protein phosphatase binding |
IPI |
23006999 |
GO:0030134 |
Component |
COPII-coated ER to Golgi transport vesicle |
ISS |
|
GO:0030868 |
Component |
Smooth endoplasmic reticulum membrane |
ISS |
|
GO:0030897 |
Component |
HOPS complex |
IDA |
24554770 |
GO:0031201 |
Component |
SNARE complex |
IBA |
21873635 |
GO:0031201 |
Component |
SNARE complex |
IDA |
23217709 |
GO:0033116 |
Component |
Endoplasmic reticulum-Golgi intermediate compartment membrane |
IEA |
|
GO:0034497 |
Process |
Protein localization to phagophore assembly site |
IDA |
23455425 |
GO:0044233 |
Component |
Mitochondria-associated endoplasmic reticulum membrane |
IDA |
23455425 |
GO:0048278 |
Process |
Vesicle docking |
IBA |
21873635 |
GO:0097111 |
Process |
Endoplasmic reticulum-Golgi intermediate compartment organization |
IMP |
21545355 |
GO:0097352 |
Process |
Autophagosome maturation |
IDA |
28306502 |
GO:0097352 |
Process |
Autophagosome maturation |
IMP |
23217709, 24554770 |
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
P56962 |
Protein name |
Syntaxin-17 |
Protein function |
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four al |
PDB |
4WY4
,
7BV4
,
7BV6
|
Family and domains |
|
Sequence |
MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK CS
|
|
Sequence length |
302 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Melanoma |
melanoma |
rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs1563902635, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050 |
18641652 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Alopecia areata |
Alopecia Areata |
|
20596022 |
|
|
|
| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412 |