CASZ1 (castor zinc finger 1)

Gene

• Entrez ID: 54897
• Gene name: Castor zinc finger 1
• Gene symbol: CASZ1
• Synonyms: CAS11, CST, SRG, ZNF693, dJ734G22.1
• Chromosome: 1
• Chromosome location: 1p36.22
• Summary: The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT053612	hsa-miR-151a-5p	Luciferase reporter assay, qRT-PCR, Western blot	22928040
MIRT487889	hsa-miR-6784-5p	PAR-CLIP	20371350
MIRT487888	hsa-miR-1908-3p	PAR-CLIP	20371350
MIRT487887	hsa-miR-6777-5p	PAR-CLIP	20371350
MIRT487886	hsa-miR-6889-5p	PAR-CLIP	20371350
MIRT487885	hsa-miR-5090	PAR-CLIP	20371350
MIRT487884	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT487883	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT487882	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT487881	hsa-miR-3648	PAR-CLIP	20371350
MIRT487880	hsa-miR-3195	PAR-CLIP	20371350
MIRT487878	hsa-miR-4706	PAR-CLIP	20371350
MIRT487879	hsa-miR-4749-5p	PAR-CLIP	20371350
MIRT487877	hsa-miR-885-3p	PAR-CLIP	20371350
MIRT487876	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT487875	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT487874	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT487873	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT487872	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT487871	hsa-miR-486-3p	PAR-CLIP	20371350
MIRT487870	hsa-miR-4665-3p	PAR-CLIP	20371350
MIRT569207	hsa-miR-33a-3p	PAR-CLIP	20371350
MIRT569206	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT569204	hsa-miR-8068	PAR-CLIP	20371350
MIRT569205	hsa-miR-6818-5p	PAR-CLIP	20371350
MIRT569203	hsa-miR-147a	PAR-CLIP	20371350
MIRT569202	hsa-miR-5010-3p	PAR-CLIP	20371350
MIRT569201	hsa-miR-4455	PAR-CLIP	20371350
MIRT569200	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT549040	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT549039	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT549038	hsa-miR-4517	PAR-CLIP	20371350
MIRT549036	hsa-miR-648	PAR-CLIP	20371350
MIRT549035	hsa-miR-4670-3p	PAR-CLIP	20371350
MIRT549034	hsa-miR-520d-5p	PAR-CLIP	20371350
MIRT549033	hsa-miR-524-5p	PAR-CLIP	20371350
MIRT549031	hsa-miR-7975	PAR-CLIP	20371350
MIRT549040	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT549039	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT549038	hsa-miR-4517	PAR-CLIP	21572407
MIRT549037	hsa-miR-6838-3p	PAR-CLIP	21572407
MIRT549036	hsa-miR-648	PAR-CLIP	21572407
MIRT549035	hsa-miR-4670-3p	PAR-CLIP	21572407
MIRT549034	hsa-miR-520d-5p	PAR-CLIP	21572407
MIRT549033	hsa-miR-524-5p	PAR-CLIP	21572407
MIRT549032	hsa-miR-4540	PAR-CLIP	21572407
MIRT549031	hsa-miR-7975	PAR-CLIP	21572407
MIRT487889	hsa-miR-6784-5p	PAR-CLIP	23592263
MIRT487888	hsa-miR-1908-3p	PAR-CLIP	23592263
MIRT487887	hsa-miR-6777-5p	PAR-CLIP	23592263
MIRT487886	hsa-miR-6889-5p	PAR-CLIP	23592263
MIRT487885	hsa-miR-5090	PAR-CLIP	23592263
MIRT487884	hsa-miR-6775-5p	PAR-CLIP	23592263
MIRT487883	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT487882	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT487881	hsa-miR-3648	PAR-CLIP	23592263
MIRT487880	hsa-miR-3195	PAR-CLIP	23592263
MIRT487878	hsa-miR-4706	PAR-CLIP	23592263
MIRT487879	hsa-miR-4749-5p	PAR-CLIP	23592263
MIRT487877	hsa-miR-885-3p	PAR-CLIP	23592263
MIRT487876	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT487875	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT487874	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT487873	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT487872	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT487871	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT487870	hsa-miR-4665-3p	PAR-CLIP	23592263
MIRT487889	hsa-miR-6784-5p	PAR-CLIP	20371350
MIRT487888	hsa-miR-1908-3p	PAR-CLIP	20371350
MIRT487887	hsa-miR-6777-5p	PAR-CLIP	20371350
MIRT487886	hsa-miR-6889-5p	PAR-CLIP	20371350
MIRT487885	hsa-miR-5090	PAR-CLIP	20371350
MIRT487884	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT487883	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT487882	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT487881	hsa-miR-3648	PAR-CLIP	20371350
MIRT487880	hsa-miR-3195	PAR-CLIP	20371350
MIRT487878	hsa-miR-4706	PAR-CLIP	20371350
MIRT487879	hsa-miR-4749-5p	PAR-CLIP	20371350
MIRT487877	hsa-miR-885-3p	PAR-CLIP	20371350
MIRT487876	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT487875	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT487874	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT487873	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT487872	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT487871	hsa-miR-486-3p	PAR-CLIP	20371350
MIRT487870	hsa-miR-4665-3p	PAR-CLIP	20371350
MIRT569207	hsa-miR-33a-3p	PAR-CLIP	20371350
MIRT569206	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT569204	hsa-miR-8068	PAR-CLIP	20371350
MIRT569205	hsa-miR-6818-5p	PAR-CLIP	20371350
MIRT569203	hsa-miR-147a	PAR-CLIP	20371350
MIRT569202	hsa-miR-5010-3p	PAR-CLIP	20371350
MIRT569201	hsa-miR-4455	PAR-CLIP	20371350
MIRT569200	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT549040	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT549039	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT549038	hsa-miR-4517	PAR-CLIP	20371350
MIRT549036	hsa-miR-648	PAR-CLIP	20371350
MIRT549035	hsa-miR-4670-3p	PAR-CLIP	20371350
MIRT549034	hsa-miR-520d-5p	PAR-CLIP	20371350
MIRT549033	hsa-miR-524-5p	PAR-CLIP	20371350
MIRT549031	hsa-miR-7975	PAR-CLIP	20371350
MIRT549040	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT549039	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT549038	hsa-miR-4517	PAR-CLIP	21572407
MIRT549037	hsa-miR-6838-3p	PAR-CLIP	21572407
MIRT549036	hsa-miR-648	PAR-CLIP	21572407
MIRT549035	hsa-miR-4670-3p	PAR-CLIP	21572407
MIRT549034	hsa-miR-520d-5p	PAR-CLIP	21572407
MIRT549033	hsa-miR-524-5p	PAR-CLIP	21572407
MIRT549032	hsa-miR-4540	PAR-CLIP	21572407
MIRT549031	hsa-miR-7975	PAR-CLIP	21572407
MIRT487889	hsa-miR-6784-5p	PAR-CLIP	23592263
MIRT487888	hsa-miR-1908-3p	PAR-CLIP	23592263
MIRT487887	hsa-miR-6777-5p	PAR-CLIP	23592263
MIRT487886	hsa-miR-6889-5p	PAR-CLIP	23592263
MIRT487885	hsa-miR-5090	PAR-CLIP	23592263
MIRT487884	hsa-miR-6775-5p	PAR-CLIP	23592263
MIRT487883	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT487882	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT487881	hsa-miR-3648	PAR-CLIP	23592263
MIRT487880	hsa-miR-3195	PAR-CLIP	23592263
MIRT487878	hsa-miR-4706	PAR-CLIP	23592263
MIRT487879	hsa-miR-4749-5p	PAR-CLIP	23592263
MIRT487877	hsa-miR-885-3p	PAR-CLIP	23592263
MIRT487876	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT487875	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT487874	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT487873	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT487872	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT487871	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT487870	hsa-miR-4665-3p	PAR-CLIP	23592263
MIRT864326	hsa-miR-1226	CLIP-seq
MIRT864327	hsa-miR-1237	CLIP-seq
MIRT864328	hsa-miR-125a-5p	CLIP-seq
MIRT864329	hsa-miR-125b	CLIP-seq
MIRT864330	hsa-miR-1283	CLIP-seq
MIRT864331	hsa-miR-1297	CLIP-seq
MIRT864332	hsa-miR-1323	CLIP-seq
MIRT864333	hsa-miR-1324	CLIP-seq
MIRT864334	hsa-miR-135a	CLIP-seq
MIRT864335	hsa-miR-135b	CLIP-seq
MIRT864336	hsa-miR-145	CLIP-seq
MIRT864337	hsa-miR-1470	CLIP-seq
MIRT864338	hsa-miR-148a	CLIP-seq
MIRT864339	hsa-miR-148b	CLIP-seq
MIRT864340	hsa-miR-151-3p	CLIP-seq
MIRT864341	hsa-miR-151-5p	CLIP-seq
MIRT864342	hsa-miR-151b	CLIP-seq
MIRT864343	hsa-miR-152	CLIP-seq
MIRT864344	hsa-miR-198	CLIP-seq
MIRT864345	hsa-miR-19a	CLIP-seq
MIRT864346	hsa-miR-19b	CLIP-seq
MIRT864347	hsa-miR-2116	CLIP-seq
MIRT864348	hsa-miR-2355-5p	CLIP-seq
MIRT864349	hsa-miR-26a	CLIP-seq
MIRT864350	hsa-miR-26b	CLIP-seq
MIRT864351	hsa-miR-3130-3p	CLIP-seq
MIRT864352	hsa-miR-3132	CLIP-seq
MIRT864353	hsa-miR-3148	CLIP-seq
MIRT864354	hsa-miR-3150b-3p	CLIP-seq
MIRT864355	hsa-miR-3160-5p	CLIP-seq
MIRT864356	hsa-miR-3182	CLIP-seq
MIRT864357	hsa-miR-3185	CLIP-seq
MIRT864358	hsa-miR-324-5p	CLIP-seq
MIRT864359	hsa-miR-335	CLIP-seq
MIRT864360	hsa-miR-339-5p	CLIP-seq
MIRT864361	hsa-miR-3529	CLIP-seq
MIRT864362	hsa-miR-3611	CLIP-seq
MIRT864363	hsa-miR-361-3p	CLIP-seq
MIRT864364	hsa-miR-3655	CLIP-seq
MIRT864365	hsa-miR-3663-3p	CLIP-seq
MIRT864366	hsa-miR-3667-3p	CLIP-seq
MIRT864367	hsa-miR-3668	CLIP-seq
MIRT864368	hsa-miR-3671	CLIP-seq
MIRT864369	hsa-miR-3673	CLIP-seq
MIRT864370	hsa-miR-3679-3p	CLIP-seq
MIRT864371	hsa-miR-3690	CLIP-seq
MIRT864372	hsa-miR-3692	CLIP-seq
MIRT864373	hsa-miR-375	CLIP-seq
MIRT864374	hsa-miR-379	CLIP-seq
MIRT864375	hsa-miR-3908	CLIP-seq
MIRT864376	hsa-miR-4254	CLIP-seq
MIRT864377	hsa-miR-4263	CLIP-seq
MIRT864378	hsa-miR-4273	CLIP-seq
MIRT864379	hsa-miR-4277	CLIP-seq
MIRT864380	hsa-miR-4286	CLIP-seq
MIRT864381	hsa-miR-4304	CLIP-seq
MIRT864382	hsa-miR-4319	CLIP-seq
MIRT864383	hsa-miR-4326	CLIP-seq
MIRT864384	hsa-miR-4446-5p	CLIP-seq
MIRT864385	hsa-miR-4463	CLIP-seq
MIRT864386	hsa-miR-4465	CLIP-seq
MIRT864387	hsa-miR-4469	CLIP-seq
MIRT864388	hsa-miR-4499	CLIP-seq
MIRT864389	hsa-miR-4652-3p	CLIP-seq
MIRT864390	hsa-miR-4659a-3p	CLIP-seq
MIRT864391	hsa-miR-4659b-3p	CLIP-seq
MIRT864392	hsa-miR-4660	CLIP-seq
MIRT864393	hsa-miR-4667-3p	CLIP-seq
MIRT864394	hsa-miR-4677-5p	CLIP-seq
MIRT864395	hsa-miR-4684-5p	CLIP-seq
MIRT864396	hsa-miR-4691-5p	CLIP-seq
MIRT864397	hsa-miR-4707-5p	CLIP-seq
MIRT864398	hsa-miR-4732-3p	CLIP-seq
MIRT864399	hsa-miR-4733-5p	CLIP-seq
MIRT864400	hsa-miR-4755-5p	CLIP-seq
MIRT864401	hsa-miR-4778-3p	CLIP-seq
MIRT864402	hsa-miR-4784	CLIP-seq
MIRT864403	hsa-miR-4786-5p	CLIP-seq
MIRT864404	hsa-miR-4789-3p	CLIP-seq
MIRT864405	hsa-miR-483-3p	CLIP-seq
MIRT864406	hsa-miR-513a-3p	CLIP-seq
MIRT864407	hsa-miR-548c-3p	CLIP-seq
MIRT864408	hsa-miR-548o	CLIP-seq
MIRT864409	hsa-miR-571	CLIP-seq
MIRT864410	hsa-miR-576-5p	CLIP-seq
MIRT864411	hsa-miR-578	CLIP-seq
MIRT864412	hsa-miR-593	CLIP-seq
MIRT864413	hsa-miR-656	CLIP-seq
MIRT864414	hsa-miR-670	CLIP-seq
MIRT864415	hsa-miR-764	CLIP-seq
MIRT864416	hsa-miR-767-5p	CLIP-seq
MIRT864417	hsa-miR-2276	CLIP-seq
MIRT864418	hsa-miR-4287	CLIP-seq
MIRT864387	hsa-miR-4469	CLIP-seq
MIRT864419	hsa-miR-4685-3p	CLIP-seq
MIRT864420	hsa-miR-4708-3p	CLIP-seq
MIRT864421	hsa-miR-4713-5p	CLIP-seq
MIRT1956189	hsa-miR-1178	CLIP-seq
MIRT1956190	hsa-miR-1247	CLIP-seq
MIRT864330	hsa-miR-1283	CLIP-seq
MIRT1956191	hsa-miR-1285	CLIP-seq
MIRT864331	hsa-miR-1297	CLIP-seq
MIRT864337	hsa-miR-1470	CLIP-seq
MIRT1956192	hsa-miR-15a	CLIP-seq
MIRT1956193	hsa-miR-15b	CLIP-seq
MIRT1956194	hsa-miR-16	CLIP-seq
MIRT1956195	hsa-miR-1910	CLIP-seq
MIRT1956196	hsa-miR-195	CLIP-seq
MIRT1956197	hsa-miR-1973	CLIP-seq
MIRT864349	hsa-miR-26a	CLIP-seq
MIRT864350	hsa-miR-26b	CLIP-seq
MIRT1956198	hsa-miR-3187-5p	CLIP-seq
MIRT1956199	hsa-miR-3605-3p	CLIP-seq
MIRT864363	hsa-miR-361-3p	CLIP-seq
MIRT1956200	hsa-miR-3657	CLIP-seq
MIRT1956201	hsa-miR-3686	CLIP-seq
MIRT1956202	hsa-miR-378g	CLIP-seq
MIRT1956203	hsa-miR-3918	CLIP-seq
MIRT1956204	hsa-miR-424	CLIP-seq
MIRT864386	hsa-miR-4465	CLIP-seq
MIRT864387	hsa-miR-4469	CLIP-seq
MIRT1956205	hsa-miR-4486	CLIP-seq
MIRT864393	hsa-miR-4667-3p	CLIP-seq
MIRT1956206	hsa-miR-4669	CLIP-seq
MIRT864397	hsa-miR-4707-5p	CLIP-seq
MIRT1956207	hsa-miR-4738-5p	CLIP-seq
MIRT1956208	hsa-miR-4742-3p	CLIP-seq
MIRT864405	hsa-miR-483-3p	CLIP-seq
MIRT1956209	hsa-miR-497	CLIP-seq
MIRT1956210	hsa-miR-612	CLIP-seq
MIRT1956211	hsa-miR-760	CLIP-seq
MIRT2193842	hsa-miR-1229	CLIP-seq
MIRT864330	hsa-miR-1283	CLIP-seq
MIRT864337	hsa-miR-1470	CLIP-seq
MIRT864338	hsa-miR-148a	CLIP-seq
MIRT864339	hsa-miR-148b	CLIP-seq
MIRT864341	hsa-miR-151-5p	CLIP-seq
MIRT864342	hsa-miR-151b	CLIP-seq
MIRT864343	hsa-miR-152	CLIP-seq
MIRT2193843	hsa-miR-1908	CLIP-seq
MIRT2193844	hsa-miR-197	CLIP-seq
MIRT864347	hsa-miR-2116	CLIP-seq
MIRT864351	hsa-miR-3130-3p	CLIP-seq
MIRT864354	hsa-miR-3150b-3p	CLIP-seq
MIRT864355	hsa-miR-3160-5p	CLIP-seq
MIRT864363	hsa-miR-361-3p	CLIP-seq
MIRT2193845	hsa-miR-3621	CLIP-seq
MIRT864369	hsa-miR-3673	CLIP-seq
MIRT1956201	hsa-miR-3686	CLIP-seq
MIRT2193846	hsa-miR-3937	CLIP-seq
MIRT864378	hsa-miR-4273	CLIP-seq
MIRT864379	hsa-miR-4277	CLIP-seq
MIRT2193847	hsa-miR-4527	CLIP-seq
MIRT2193848	hsa-miR-4639-3p	CLIP-seq
MIRT864390	hsa-miR-4659a-3p	CLIP-seq
MIRT864391	hsa-miR-4659b-3p	CLIP-seq
MIRT864392	hsa-miR-4660	CLIP-seq
MIRT864393	hsa-miR-4667-3p	CLIP-seq
MIRT864397	hsa-miR-4707-5p	CLIP-seq
MIRT1956208	hsa-miR-4742-3p	CLIP-seq
MIRT2193849	hsa-miR-4757-5p	CLIP-seq
MIRT864402	hsa-miR-4784	CLIP-seq
MIRT864403	hsa-miR-4786-5p	CLIP-seq
MIRT2193850	hsa-miR-4793-3p	CLIP-seq
MIRT2193851	hsa-miR-4797-5p	CLIP-seq
MIRT864409	hsa-miR-571	CLIP-seq
MIRT2193852	hsa-miR-663	CLIP-seq
MIRT864415	hsa-miR-764	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IDA	27693370
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	27693370
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	27693370
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of transcription, DNA-templated	IBA	21873635
GO:0007275	Process	Multicellular organism development	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA
GO:0045664	Process	Regulation of neuron differentiation	IBA	21873635
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IDA	27693370
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	27693370
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 609895
• HGNC: 26002
• e!Ensembl: ENSG00000130940

Protein

• UniProt ID: Q86V15
• Protein name: Zinc finger protein castor homolog 1 (Castor-related protein) (Putative survival-related protein) (Zinc finger protein 693)
• Protein function: Transcriptional activator (PubMed:23639441, PubMed:27693370). Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7 (PubMed:23639441).
• Sequence:

  MDLGTAEGTRCTDPPAGKPAMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQ
  PRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLGRIAREGLELPPEG
  VYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAAS
  TMTEFLGMFGYDDQNTRDELARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYE
  EYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLETKATILPLPSHSSV
  QMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMG
  GAIAFKTGKVGRPSKYDVRGIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASL
  SFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHI
  HCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYH
  GCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADC
  QFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCV
  YSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEES
  SNDDLVDFSALSSKNSSLSASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGL
  PGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSAASATPDTPTLV
  ASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVT
  PARFPPAQVKPEPGESTGAPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNK
  MSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWKVYLRRFGTKDFCD
  GQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKP
  PMAPSSPPVPPVTTATVSSLEGPAPSPASVPSTPTLLAWKQLASTIPQMPQIPASVPHLP
  ASPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAE
  SHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLP
  WHIKKHEKAERRAANGFKYFTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSH
  ARKHMRRMLGKNFDRVPPSQGPPGLMDAETDECMDYTGCSPGAMSSESSTMDRSCSSTPV
  GNESTAAGNTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLY
  EDCKDAACQFSLKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLS
  CHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVP
  DCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQERGEPAAEGPAPGPPISLDGSL
  SLGAEPGSLLFLQSAAAGLGLALGDAGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEE
  ELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAEAAGAGARTPAL
  AALAALGAPGPAPTAASSP

• Sequence length: 1759

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Atrial fibrillation	Atrial Fibrillation	rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557, rs587777558, rs587777559, rs587777560, rs886037778, rs769405762, rs770372675	30061737, 29892015
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	29059683
Chronic obstructive pulmonary disease	Chronic Obstructive Airway Disease	rs2227956, rs1008438, rs1043618, rs562047, rs1061581, rs2763979, rs6457452, rs13147758, rs1828591, rs13118928	30940143
Hypertension	Hypertensive disease	rs13306026, rs13333226	25249183, 30487518, 31545351
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	29662167

Unknown
Disease name	Disease term	dbSNP ID	References
Alopecia	Alopecia		28196072
Cardiovascular diseases	Cardiovascular Diseases		30595370
Ischemic stroke	Ischemic stroke	rs6025, rs1799963, rs1799983	29531354
Paroxysmal atrial fibrillation	Paroxysmal atrial fibrillation	rs199865688, rs397515994, rs757096307	30061737, 29892015
Prostatic neoplasms	Prostatic Neoplasms		29662167
Stroke	Cerebrovascular accident, Acute Cerebrovascular Accidents		29531354
Vulval varices	Varicosity		30566020, 30998689