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CNTLN (centlein)

Gene

Centlein

CNTLN

C9orf101, C9orf39, bA340N12.1

9

9p22.2

Show/Hide all(116)

miRTarBase ID	miRNA	Experiments	Reference
MIRT029145	hsa-miR-26b-5p	Microarray	19088304
MIRT047533	hsa-miR-10a-5p	CLASH	23622248
MIRT572615	hsa-miR-548m	PAR-CLIP	20371350
MIRT572616	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT572614	hsa-miR-545-5p	PAR-CLIP	20371350
MIRT572613	hsa-miR-222-5p	PAR-CLIP	20371350
MIRT572612	hsa-miR-8055	PAR-CLIP	20371350
MIRT572611	hsa-miR-129-5p	PAR-CLIP	20371350
MIRT572611	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT572612	hsa-miR-8055	HITS-CLIP	27418678
MIRT572615	hsa-miR-548m	PAR-CLIP	20371350
MIRT572616	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT572614	hsa-miR-545-5p	PAR-CLIP	20371350
MIRT572613	hsa-miR-222-5p	PAR-CLIP	20371350
MIRT572612	hsa-miR-8055	PAR-CLIP	20371350
MIRT572611	hsa-miR-129-5p	PAR-CLIP	20371350
MIRT901568	hsa-miR-1206	CLIP-seq
MIRT901569	hsa-miR-1272	CLIP-seq
MIRT901570	hsa-miR-1301	CLIP-seq
MIRT901571	hsa-miR-1322	CLIP-seq
MIRT901572	hsa-miR-137	CLIP-seq
MIRT901573	hsa-miR-145	CLIP-seq
MIRT901574	hsa-miR-188-3p	CLIP-seq
MIRT901575	hsa-miR-203	CLIP-seq
MIRT901576	hsa-miR-2052	CLIP-seq
MIRT901577	hsa-miR-25	CLIP-seq
MIRT901578	hsa-miR-3129-3p	CLIP-seq
MIRT901579	hsa-miR-3189-3p	CLIP-seq
MIRT901580	hsa-miR-32	CLIP-seq
MIRT901581	hsa-miR-3609	CLIP-seq
MIRT901582	hsa-miR-3611	CLIP-seq
MIRT901583	hsa-miR-363	CLIP-seq
MIRT901584	hsa-miR-3668	CLIP-seq
MIRT901585	hsa-miR-367	CLIP-seq
MIRT901586	hsa-miR-383	CLIP-seq
MIRT901587	hsa-miR-3919	CLIP-seq
MIRT901588	hsa-miR-4272	CLIP-seq
MIRT901589	hsa-miR-4290	CLIP-seq
MIRT901590	hsa-miR-4327	CLIP-seq
MIRT901591	hsa-miR-4328	CLIP-seq
MIRT901592	hsa-miR-4452	CLIP-seq
MIRT901593	hsa-miR-4660	CLIP-seq
MIRT901594	hsa-miR-4667-3p	CLIP-seq
MIRT901595	hsa-miR-4668-3p	CLIP-seq
MIRT901596	hsa-miR-4687-5p	CLIP-seq
MIRT901597	hsa-miR-4698	CLIP-seq
MIRT901598	hsa-miR-4699-5p	CLIP-seq
MIRT901599	hsa-miR-4732-5p	CLIP-seq
MIRT901600	hsa-miR-4735-5p	CLIP-seq
MIRT901601	hsa-miR-4756-3p	CLIP-seq
MIRT901602	hsa-miR-4775	CLIP-seq
MIRT901603	hsa-miR-4785	CLIP-seq
MIRT901604	hsa-miR-488	CLIP-seq
MIRT901605	hsa-miR-5047	CLIP-seq
MIRT901606	hsa-miR-545	CLIP-seq
MIRT901607	hsa-miR-548ah	CLIP-seq
MIRT901608	hsa-miR-548g	CLIP-seq
MIRT901609	hsa-miR-548n	CLIP-seq
MIRT901610	hsa-miR-548t	CLIP-seq
MIRT901611	hsa-miR-590-3p	CLIP-seq
MIRT901612	hsa-miR-758	CLIP-seq
MIRT901613	hsa-miR-92a	CLIP-seq
MIRT901614	hsa-miR-92b	CLIP-seq
MIRT901597	hsa-miR-4698	CLIP-seq
MIRT2203132	hsa-miR-4707-3p	CLIP-seq
MIRT2203133	hsa-miR-221	CLIP-seq
MIRT2203134	hsa-miR-222	CLIP-seq
MIRT2203135	hsa-miR-4704-5p	CLIP-seq
MIRT2203136	hsa-miR-548v	CLIP-seq
MIRT2386302	hsa-miR-1827	CLIP-seq
MIRT2386303	hsa-miR-299-3p	CLIP-seq
MIRT2386304	hsa-miR-3612	CLIP-seq
MIRT2386305	hsa-miR-3689a-3p	CLIP-seq
MIRT2386306	hsa-miR-3689c	CLIP-seq
MIRT2386307	hsa-miR-4269	CLIP-seq
MIRT2386308	hsa-miR-4648	CLIP-seq
MIRT2386309	hsa-miR-4654	CLIP-seq
MIRT2386310	hsa-miR-4728-5p	CLIP-seq
MIRT2386311	hsa-miR-4769-5p	CLIP-seq
MIRT2386312	hsa-miR-650	CLIP-seq
MIRT2386313	hsa-miR-940	CLIP-seq
MIRT2447404	hsa-miR-1281	CLIP-seq
MIRT2447405	hsa-miR-1297	CLIP-seq
MIRT2447406	hsa-miR-150	CLIP-seq
MIRT2447407	hsa-miR-1915	CLIP-seq
MIRT2447408	hsa-miR-1976	CLIP-seq
MIRT2447409	hsa-miR-26a	CLIP-seq
MIRT2447410	hsa-miR-26b	CLIP-seq
MIRT2447411	hsa-miR-4279	CLIP-seq
MIRT2447412	hsa-miR-4465	CLIP-seq
MIRT2447413	hsa-miR-4722-3p	CLIP-seq
MIRT2447414	hsa-miR-4726-3p	CLIP-seq
MIRT2447404	hsa-miR-1281	CLIP-seq
MIRT2447405	hsa-miR-1297	CLIP-seq
MIRT2447406	hsa-miR-150	CLIP-seq
MIRT2447407	hsa-miR-1915	CLIP-seq
MIRT2447408	hsa-miR-1976	CLIP-seq
MIRT2447409	hsa-miR-26a	CLIP-seq
MIRT2447410	hsa-miR-26b	CLIP-seq
MIRT2447411	hsa-miR-4279	CLIP-seq
MIRT2447412	hsa-miR-4465	CLIP-seq
MIRT2447413	hsa-miR-4722-3p	CLIP-seq
MIRT2447414	hsa-miR-4726-3p	CLIP-seq
MIRT2506146	hsa-miR-562	CLIP-seq
MIRT2447404	hsa-miR-1281	CLIP-seq
MIRT2447405	hsa-miR-1297	CLIP-seq
MIRT2447406	hsa-miR-150	CLIP-seq
MIRT2447407	hsa-miR-1915	CLIP-seq
MIRT2447408	hsa-miR-1976	CLIP-seq
MIRT2447409	hsa-miR-26a	CLIP-seq
MIRT2447410	hsa-miR-26b	CLIP-seq
MIRT2447411	hsa-miR-4279	CLIP-seq
MIRT2447412	hsa-miR-4465	CLIP-seq
MIRT2447413	hsa-miR-4722-3p	CLIP-seq
MIRT2447414	hsa-miR-4726-3p	CLIP-seq
MIRT2506146	hsa-miR-562	CLIP-seq

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	24554434
GO:0005813	Component	Centrosome	IBA	21873635
GO:0005813	Component	Centrosome	IDA
GO:0005814	Component	Centriole	IBA	21873635
GO:0005814	Component	Centriole	IDA	24554434
GO:0005829	Component	Cytosol	IDA
GO:0010457	Process	Centriole-centriole cohesion	IBA	21873635
GO:0010457	Process	Centriole-centriole cohesion	IMP	24554434
GO:0019901	Function	Protein kinase binding	IPI	24554434
GO:0019904	Function	Protein domain specific binding	IPI	24554434
GO:0030674	Function	Protein-macromolecule adaptor activity	IMP	24554434
GO:0033365	Process	Protein localization to organelle	IBA	21873635
GO:0033365	Process	Protein localization to organelle	IMP	24554434
GO:0070062	Component	Extracellular exosome	HDA	19056867

MIM	HGNC	e!Ensembl
611870	23432	ENSG00000044459

Protein

UniProt ID

Protein name

Centlein (Centrosomal protein)

Protein function

Required for centrosome cohesion and recruitment of CEP68 to centrosomes.

Family and domains

Sequence

MAARSPPSPHPSPPARQLGPRSPRVGRGAEVHAMRSEASGFAGAAREVVADESDKIWVGE
EGSGGRRGPGGAAPAHAPLLSAPMGSRRLEGISVEEAMVTRTQLLEEELSSLKEELALCQ
ADKEFVWSLWKRLQVTNPDLTQVVSLVVEREKQKSEAKDRKVLEILQVKDAKIQEFEQRE
SVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVI
KNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQ
SKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVLNM
DTQKVLRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENA
KLKEKLQESQGAPLPLPQESDPDYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANE
KLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIEN
LEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADP
QQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAER
REEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMK
ENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAE
ANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKVKFKAAKKNCSVG
RHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDG
KDQKESDPTEDSQTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQKKNCKMQKSSHTAV
PTRVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLL
HQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQ
VTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRME
RDITMKRHLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLN
VAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSE
QVLEGAQKTLLLANEKVEEFTTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTH
KAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAENDKEWMLYIQKLLEGQSLTLSPR
LKCNGAIVAHQNLRLPDSSSSASAS

Sequence length

1405

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (2)

Causal
Disease name	Disease term	dbSNP ID	References
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs4402960, rs1362648752, rs3745368, rs3792267, rs3842570, rs5030952, rs2975760, rs119489103, rs7903146, rs12255372, rs11196205, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs137852740, rs137852786, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs80356663, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356666, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs387906779, rs141804752, rs182349376, rs184917682, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs61736969, rs587783673, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs797045623, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs1553638903, rs1553638909, rs948820149, rs371977235, rs1553784995, rs76474829, rs200998587, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs776793516, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	21799836
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601	27903959

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