Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
5453 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
POU class 3 homeobox 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
POU3F1 |
SynonymsGene synonyms aliases
|
OCT6, OTF6, SCIP |
ChromosomeChromosome number
|
1 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
1p34.3 |
miRNAmiRNA information provided by mirtarbase database.
|
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0000785 |
Component |
Chromatin |
ISA |
|
GO:0000978 |
Function |
RNA polymerase II cis-regulatory region sequence-specific DNA binding |
IBA |
21873635 |
GO:0000981 |
Function |
DNA-binding transcription factor activity, RNA polymerase II-specific |
IBA |
21873635 |
GO:0000981 |
Function |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ISA |
|
GO:0003700 |
Function |
DNA-binding transcription factor activity |
TAS |
8451175, 8662541 |
GO:0005634 |
Component |
Nucleus |
ISS |
|
GO:0005654 |
Component |
Nucleoplasm |
IDA |
|
GO:0005667 |
Component |
Transcription regulator complex |
IEA |
|
GO:0006357 |
Process |
Regulation of transcription by RNA polymerase II |
IBA |
21873635 |
GO:0008366 |
Process |
Axon ensheathment |
TAS |
8662541 |
GO:0010628 |
Process |
Positive regulation of gene expression |
ISS |
|
GO:0022011 |
Process |
Myelination in peripheral nervous system |
IEA |
|
GO:0030216 |
Process |
Keratinocyte differentiation |
IEA |
|
GO:0030900 |
Process |
Forebrain development |
IEA |
|
GO:0043565 |
Function |
Sequence-specific DNA binding |
IDA |
9242494 |
GO:0045893 |
Process |
Positive regulation of transcription, DNA-templated |
ISS |
|
GO:1990837 |
Function |
Sequence-specific double-stranded DNA binding |
IDA |
28473536 |
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q03052 |
Protein name |
POU domain, class 3, transcription factor 1 (Octamer-binding protein 6) (Oct-6) (Octamer-binding transcription factor 6) (OTF-6) (POU domain transcription factor SCIP) |
Protein function |
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') (By similarity). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity). Acts as a transcriptional repress |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00157 |
Pou |
250 → 321 |
Pou domain - N-terminal to homeobox domain |
Domain |
PF00046 |
Homeodomain |
340 → 396 |
Homeodomain |
Domain |
|
Sequence |
|
Sequence length |
451 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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