ZDHHC13 (zDHHC palmitoyltransferase 13)

Gene

• Entrez ID: 54503
• Gene name: ZDHHC palmitoyltransferase 13
• Gene symbol: ZDHHC13
• Synonyms: HIP14L, HIP3RP
• Chromosome: 11
• Chromosome location: 11p15.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1507716	hsa-miR-146a	CLIP-seq
MIRT1507717	hsa-miR-146b-5p	CLIP-seq
MIRT1507718	hsa-miR-2054	CLIP-seq
MIRT1507719	hsa-miR-361-5p	CLIP-seq
MIRT1507720	hsa-miR-365	CLIP-seq
MIRT1507721	hsa-miR-4263	CLIP-seq
MIRT1507722	hsa-miR-4461	CLIP-seq
MIRT1507723	hsa-miR-4766-3p	CLIP-seq
MIRT1507724	hsa-miR-4799-5p	CLIP-seq
MIRT1507725	hsa-miR-532-5p	CLIP-seq
MIRT1507726	hsa-miR-548p	CLIP-seq
MIRT1507727	hsa-miR-576-5p	CLIP-seq
MIRT1507728	hsa-miR-580	CLIP-seq
MIRT1507729	hsa-miR-589	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IBA	21873635
GO:0000139	Component	Golgi membrane	ISS
GO:0005783	Component	Endoplasmic reticulum	IDA	16647879
GO:0015095	Function	Magnesium ion transmembrane transporter activity	ISS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016021	Component	Integral component of membrane	IEA
GO:0016409	Function	Palmitoyltransferase activity	IBA	21873635
GO:0016409	Function	Palmitoyltransferase activity	ISS
GO:0018215	Process	Protein phosphopantetheinylation	IEA
GO:0018345	Process	Protein palmitoylation	IBA	21873635
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IEA
GO:0030659	Component	Cytoplasmic vesicle membrane	IEA
GO:0030660	Component	Golgi-associated vesicle membrane	ISS
GO:0043123	Process	Positive regulation of I-kappaB kinase/NF-kappaB signaling	HMP	12761501
GO:1903830	Process	Magnesium ion transmembrane transport	IEA

Other IDs

• MIM: 612815
• HGNC: 18413
• e!Ensembl: ENSG00000177054

Protein

• UniProt ID: Q8IUH4
• Protein name: Palmitoyltransferase ZDHHC13 (EC 2.3.1.225) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin-interacting protein HIP3RP) (Putative MAPK-activating protein PM03) (Putative NF-kappa-B-activating protein 209) (Zinc fing
• Protein function: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (By similarity). Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	53 → 146	Ankyrin repeats (3 copies)	Repeat
  PF13637	Ank_4	217 → 271		Repeat
  PF01529	DHHC	421 → 559	DHHC palmitoyltransferase	Family

• Sequence:

  MEGPGLGSQCRNHSHGPHPPGFGRYGICAHENKELANAREALPLIEDSSNCDIVKATQYG
  IFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPL
  HWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDV
  NGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAG
  SSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRANQKFRLWRWLQKCELFLLLMLSV
  ITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLSSVFWIF
  MTWFILFFPDLAGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAETG
  SLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSM
  VCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLN
  QLFQIAFLGLTSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCV
  VDWTSQYTMVFHPAREKVLRSV

• Sequence length: 622

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Amyloidosis	Amyloidosis	rs63750567, rs63750560, rs387906821, rs387906822, rs387906823, rs1561123748, rs140352180, rs770211260, rs763065333, rs1554300664, rs747723062, rs773435101	20548961
Osteoporosis	Osteoporosis, Age-Related, Osteoporosis, Osteoporosis, Senile, Post-Traumatic Osteoporosis	rs72658152, rs72667023, rs587776916, rs72656370, rs768615287	20548961

Unknown
Disease name	Disease term	dbSNP ID	References
Alopecia	Alopecia		20548961
Alopecia, male pattern	Alopecia, Male Pattern		20548961
Androgenetic alopecia	Androgenetic Alopecia		20548961
Pseudopelade	Pseudopelade		20548961