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ZFAND6 (zinc finger AN1-type containing 6)

Gene

54469

Zinc finger AN1-type containing 6

ZFAND6

AWP1, ZA20D3, ZFAND5B

15q25.1

Show/Hide all(203)

miRTarBase ID	miRNA	Experiments	Reference
MIRT194174	hsa-miR-181a-5p	HITS-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	HITS-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	HITS-CLIP	21572407
MIRT194180	hsa-miR-4262	HITS-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	HITS-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT194179	hsa-miR-580-5p	HITS-CLIP	21572407
MIRT282242	hsa-miR-935	HITS-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	20371350
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	20371350
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	20371350
MIRT194180	hsa-miR-4262	PAR-CLIP	20371350
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	20371350
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	20371350
MIRT194179	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT282242	hsa-miR-935	PAR-CLIP	20371350
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	21572407
MIRT194180	hsa-miR-4262	PAR-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT194179	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT282242	hsa-miR-935	PAR-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	23446348
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	23446348
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	23446348
MIRT194180	hsa-miR-4262	PAR-CLIP	23446348
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	23446348
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	23446348
MIRT194179	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT282242	hsa-miR-935	PAR-CLIP	23446348
MIRT194174	hsa-miR-181a-5p	HITS-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	HITS-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	HITS-CLIP	21572407
MIRT194180	hsa-miR-4262	HITS-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	HITS-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT194179	hsa-miR-580-5p	HITS-CLIP	21572407
MIRT282242	hsa-miR-935	HITS-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	20371350
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	20371350
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	20371350
MIRT194180	hsa-miR-4262	PAR-CLIP	20371350
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	20371350
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	20371350
MIRT194179	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT282242	hsa-miR-935	PAR-CLIP	20371350
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	21572407
MIRT194180	hsa-miR-4262	PAR-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT194179	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT282242	hsa-miR-935	PAR-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	23446348
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	23446348
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	23446348
MIRT194180	hsa-miR-4262	PAR-CLIP	23446348
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	23446348
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	23446348
MIRT194179	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT282242	hsa-miR-935	PAR-CLIP	23446348
MIRT1509695	hsa-miR-1264	CLIP-seq
MIRT1509696	hsa-miR-3157-5p	CLIP-seq
MIRT1509697	hsa-miR-4279	CLIP-seq
MIRT1509698	hsa-miR-4691-3p	CLIP-seq
MIRT1509699	hsa-miR-561	CLIP-seq
MIRT1509700	hsa-miR-1243	CLIP-seq
MIRT1509701	hsa-miR-155	CLIP-seq
MIRT1509702	hsa-miR-200b	CLIP-seq
MIRT1509703	hsa-miR-200c	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509705	hsa-miR-3148	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509707	hsa-miR-3654	CLIP-seq
MIRT1509708	hsa-miR-374c	CLIP-seq
MIRT1509709	hsa-miR-3908	CLIP-seq
MIRT1509710	hsa-miR-429	CLIP-seq
MIRT1509711	hsa-miR-4290	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509713	hsa-miR-4687-5p	CLIP-seq
MIRT1509714	hsa-miR-4766-5p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509716	hsa-miR-548c-3p	CLIP-seq
MIRT1509717	hsa-miR-649	CLIP-seq
MIRT1509718	hsa-miR-655	CLIP-seq
MIRT1509719	hsa-miR-875-3p	CLIP-seq
MIRT1509720	hsa-miR-1279	CLIP-seq
MIRT1509721	hsa-miR-4789-5p	CLIP-seq
MIRT1509722	hsa-miR-568	CLIP-seq
MIRT1509723	hsa-miR-1305	CLIP-seq
MIRT1509724	hsa-miR-1323	CLIP-seq
MIRT1509725	hsa-miR-181a	CLIP-seq
MIRT1509726	hsa-miR-181b	CLIP-seq
MIRT1509727	hsa-miR-181c	CLIP-seq
MIRT1509728	hsa-miR-181d	CLIP-seq
MIRT1509729	hsa-miR-2467-3p	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509730	hsa-miR-3158-5p	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509732	hsa-miR-3919	CLIP-seq
MIRT1509733	hsa-miR-4275	CLIP-seq
MIRT1509734	hsa-miR-4299	CLIP-seq
MIRT1509735	hsa-miR-4311	CLIP-seq
MIRT1509736	hsa-miR-4463	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509737	hsa-miR-4761-3p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509738	hsa-miR-539	CLIP-seq
MIRT1509739	hsa-miR-548aa	CLIP-seq
MIRT1509740	hsa-miR-548o	CLIP-seq
MIRT1509741	hsa-miR-548u	CLIP-seq
MIRT1509742	hsa-miR-607	CLIP-seq
MIRT1509743	hsa-miR-1273d	CLIP-seq
MIRT1509720	hsa-miR-1279	CLIP-seq
MIRT1509744	hsa-miR-1324	CLIP-seq
MIRT1509745	hsa-miR-19a	CLIP-seq
MIRT1509746	hsa-miR-19b	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509747	hsa-miR-3121-3p	CLIP-seq
MIRT1509748	hsa-miR-329	CLIP-seq
MIRT1509749	hsa-miR-362-3p	CLIP-seq
MIRT1509750	hsa-miR-3682-5p	CLIP-seq
MIRT1509751	hsa-miR-3941	CLIP-seq
MIRT1509752	hsa-miR-3942-3p	CLIP-seq
MIRT1509733	hsa-miR-4275	CLIP-seq
MIRT1509734	hsa-miR-4299	CLIP-seq
MIRT1509736	hsa-miR-4463	CLIP-seq
MIRT1509753	hsa-miR-4727-3p	CLIP-seq
MIRT1509721	hsa-miR-4789-5p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509754	hsa-miR-518a-5p	CLIP-seq
MIRT1509755	hsa-miR-527	CLIP-seq
MIRT1509741	hsa-miR-548u	CLIP-seq
MIRT1509722	hsa-miR-568	CLIP-seq
MIRT1509756	hsa-miR-603	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509750	hsa-miR-3682-5p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509700	hsa-miR-1243	CLIP-seq
MIRT1509701	hsa-miR-155	CLIP-seq
MIRT1509702	hsa-miR-200b	CLIP-seq
MIRT1509703	hsa-miR-200c	CLIP-seq
MIRT2666447	hsa-miR-203	CLIP-seq
MIRT2666448	hsa-miR-2276	CLIP-seq
MIRT1509729	hsa-miR-2467-3p	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509705	hsa-miR-3148	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509730	hsa-miR-3158-5p	CLIP-seq
MIRT1509707	hsa-miR-3654	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509708	hsa-miR-374c	CLIP-seq
MIRT1509709	hsa-miR-3908	CLIP-seq
MIRT1509732	hsa-miR-3919	CLIP-seq
MIRT1509710	hsa-miR-429	CLIP-seq
MIRT1509711	hsa-miR-4290	CLIP-seq
MIRT1509735	hsa-miR-4311	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509713	hsa-miR-4687-5p	CLIP-seq
MIRT2666449	hsa-miR-4696	CLIP-seq
MIRT2666450	hsa-miR-4731-3p	CLIP-seq
MIRT1509737	hsa-miR-4761-3p	CLIP-seq
MIRT2666451	hsa-miR-4801	CLIP-seq
MIRT1509738	hsa-miR-539	CLIP-seq
MIRT1509716	hsa-miR-548c-3p	CLIP-seq
MIRT2666452	hsa-miR-548g	CLIP-seq
MIRT1509718	hsa-miR-655	CLIP-seq
MIRT1509719	hsa-miR-875-3p	CLIP-seq
MIRT1509700	hsa-miR-1243	CLIP-seq
MIRT1509701	hsa-miR-155	CLIP-seq
MIRT1509702	hsa-miR-200b	CLIP-seq
MIRT1509703	hsa-miR-200c	CLIP-seq
MIRT2666447	hsa-miR-203	CLIP-seq
MIRT2666448	hsa-miR-2276	CLIP-seq
MIRT1509729	hsa-miR-2467-3p	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509705	hsa-miR-3148	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509730	hsa-miR-3158-5p	CLIP-seq
MIRT1509707	hsa-miR-3654	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509708	hsa-miR-374c	CLIP-seq
MIRT1509709	hsa-miR-3908	CLIP-seq
MIRT1509732	hsa-miR-3919	CLIP-seq
MIRT1509710	hsa-miR-429	CLIP-seq
MIRT1509711	hsa-miR-4290	CLIP-seq
MIRT1509735	hsa-miR-4311	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509713	hsa-miR-4687-5p	CLIP-seq
MIRT2666449	hsa-miR-4696	CLIP-seq
MIRT2666450	hsa-miR-4731-3p	CLIP-seq
MIRT1509737	hsa-miR-4761-3p	CLIP-seq
MIRT2666451	hsa-miR-4801	CLIP-seq
MIRT1509738	hsa-miR-539	CLIP-seq
MIRT1509716	hsa-miR-548c-3p	CLIP-seq
MIRT2666452	hsa-miR-548g	CLIP-seq
MIRT1509718	hsa-miR-655	CLIP-seq
MIRT1509719	hsa-miR-875-3p	CLIP-seq

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 21810480, 25416956, 30561431, 32296183
GO:0005575	Component	Cellular_component	ND
GO:0005829	Component	Cytosol	TAS
GO:0006625	Process	Protein targeting to peroxisome	IBA	21873635
GO:0006625	Process	Protein targeting to peroxisome	ISS
GO:0006625	Process	Protein targeting to peroxisome	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0031593	Function	Polyubiquitin modification-dependent protein binding	IBA	21873635
GO:0031593	Function	Polyubiquitin modification-dependent protein binding	ISS
GO:0043066	Process	Negative regulation of apoptotic process	IMP	21810480
GO:0043122	Process	Regulation of I-kappaB kinase/NF-kappaB signaling	IMP	21810480
GO:0071356	Process	Cellular response to tumor necrosis factor	IMP	21810480

MIM	HGNC	e!Ensembl
610183	30164	ENSG00000086666

Protein

UniProt ID

Q6FIF0

Protein name

AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3)

Protein function

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-depend

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01754	zf-A20	12 → 35	A20-like zinc finger	Family
PF01428	zf-AN1	149 → 186	AN1-like Zinc finger	Family

Sequence

MAQETNHSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPATSVSSLSE
SLPVQCTDGSVPEAQSALDSTSSSMQPSPVSNQSLLSESVASSQLDSTSVDKAVPETEDV
QASVSDTAQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHN
CSYNYKADAAEKIRKENPVVVGEKIQKI

Sequence length

208

Interactions

View interactions

	Reactome
			Peroxisomal protein import

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	27846195

Show/Hide Unknown Diseases (2)

Unknown
Disease name	Disease term	dbSNP ID	References
Arsenic encephalopathy	Arsenic Encephalopathy		16835338
Dermatologic disorders	Dermatologic disorders		16835338

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