Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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54431 |
Gene nameGene Name - the full gene name approved by the HGNC.
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DnaJ heat shock protein family (Hsp40) member C10 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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DNAJC10 |
SynonymsGene synonyms aliases
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ERdj5, JPDI, MTHr, PDIA19 |
ChromosomeChromosome number
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2 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q32.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q8IXB1 |
Protein name |
DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr) |
Protein function |
Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native dis |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00226 |
DnaJ |
35 → 97 |
DnaJ domain |
Domain |
PF00085 |
Thioredoxin |
130 → 231 |
Thioredoxin |
Domain |
PF00085 |
Thioredoxin |
454 → 552 |
Thioredoxin |
Domain |
PF00085 |
Thioredoxin |
557 → 659 |
Thioredoxin |
Domain |
PF00085 |
Thioredoxin |
671 → 777 |
Thioredoxin |
Domain |
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Sequence |
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Sequence length |
793 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
17013881 |
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Benign neoplasm |
Benign Neoplasm |
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17353921 |
Malignant neoplasm |
Malignant Neoplasms |
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17353921 |
Neoplasms |
Neoplasms |
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17353921 |
Prostatic neoplasms |
Prostatic Neoplasms |
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17013881 |
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