BTBD1 (BTB domain containing 1)

Gene

• Entrez ID: 53339
• Gene name: BTB domain containing 1
• Gene symbol: BTBD1
• Synonyms: C15orf1, NS5ATP8
• Chromosome: 15
• Chromosome location: 15q25.2
• Summary: The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in prot

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052407	hsa-let-7a-5p	CLASH	23622248
MIRT538884	hsa-miR-137	PAR-CLIP	22012620
MIRT538883	hsa-miR-6783-5p	PAR-CLIP	22012620
MIRT538882	hsa-miR-126-5p	PAR-CLIP	22012620
MIRT538881	hsa-miR-4795-5p	PAR-CLIP	22012620
MIRT538880	hsa-miR-4755-3p	PAR-CLIP	22012620
MIRT538879	hsa-miR-4471	PAR-CLIP	22012620
MIRT538878	hsa-miR-8059	PAR-CLIP	22012620
MIRT538877	hsa-miR-4795-3p	PAR-CLIP	22012620
MIRT538876	hsa-miR-3616-5p	PAR-CLIP	22012620
MIRT538875	hsa-miR-573	PAR-CLIP	22012620
MIRT538874	hsa-miR-1202	PAR-CLIP	22012620
MIRT538873	hsa-miR-3972	PAR-CLIP	22012620
MIRT538872	hsa-miR-5006-5p	PAR-CLIP	22012620
MIRT538871	hsa-miR-4482-3p	PAR-CLIP	22012620
MIRT441102	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT441101	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT441102	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT441101	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT728191	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT728189	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT728190	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT728188	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT728187	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT538884	hsa-miR-137	PAR-CLIP	22012620
MIRT538883	hsa-miR-6783-5p	PAR-CLIP	22012620
MIRT538882	hsa-miR-126-5p	PAR-CLIP	22012620
MIRT538881	hsa-miR-4795-5p	PAR-CLIP	22012620
MIRT538880	hsa-miR-4755-3p	PAR-CLIP	22012620
MIRT538879	hsa-miR-4471	PAR-CLIP	22012620
MIRT538878	hsa-miR-8059	PAR-CLIP	22012620
MIRT538877	hsa-miR-4795-3p	PAR-CLIP	22012620
MIRT538876	hsa-miR-3616-5p	PAR-CLIP	22012620
MIRT538875	hsa-miR-573	PAR-CLIP	22012620
MIRT538874	hsa-miR-1202	PAR-CLIP	22012620
MIRT538873	hsa-miR-3972	PAR-CLIP	22012620
MIRT538872	hsa-miR-5006-5p	PAR-CLIP	22012620
MIRT538871	hsa-miR-4482-3p	PAR-CLIP	22012620
MIRT826264	hsa-miR-106a	CLIP-seq
MIRT826265	hsa-miR-106b	CLIP-seq
MIRT826266	hsa-miR-1237	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT826269	hsa-miR-1283	CLIP-seq
MIRT826270	hsa-miR-142-5p	CLIP-seq
MIRT826271	hsa-miR-17	CLIP-seq
MIRT826272	hsa-miR-20a	CLIP-seq
MIRT826273	hsa-miR-20b	CLIP-seq
MIRT826274	hsa-miR-3128	CLIP-seq
MIRT826275	hsa-miR-326	CLIP-seq
MIRT826276	hsa-miR-330-5p	CLIP-seq
MIRT826277	hsa-miR-338-5p	CLIP-seq
MIRT826278	hsa-miR-340	CLIP-seq
MIRT826279	hsa-miR-3609	CLIP-seq
MIRT826280	hsa-miR-362-5p	CLIP-seq
MIRT826281	hsa-miR-3945	CLIP-seq
MIRT826282	hsa-miR-410	CLIP-seq
MIRT826283	hsa-miR-4253	CLIP-seq
MIRT826284	hsa-miR-4427	CLIP-seq
MIRT826285	hsa-miR-4661-5p	CLIP-seq
MIRT826286	hsa-miR-4684-5p	CLIP-seq
MIRT826287	hsa-miR-4698	CLIP-seq
MIRT826288	hsa-miR-4720-5p	CLIP-seq
MIRT826289	hsa-miR-4724-3p	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826291	hsa-miR-4796-3p	CLIP-seq
MIRT826292	hsa-miR-4799-3p	CLIP-seq
MIRT826293	hsa-miR-487a	CLIP-seq
MIRT826294	hsa-miR-495	CLIP-seq
MIRT826295	hsa-miR-500b	CLIP-seq
MIRT826296	hsa-miR-501-5p	CLIP-seq
MIRT826297	hsa-miR-519d	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826299	hsa-miR-548ah	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT826305	hsa-miR-93	CLIP-seq
MIRT826306	hsa-miR-942	CLIP-seq
MIRT826307	hsa-miR-1257	CLIP-seq
MIRT826308	hsa-miR-1267	CLIP-seq
MIRT826309	hsa-miR-140-5p	CLIP-seq
MIRT826310	hsa-miR-2113	CLIP-seq
MIRT826311	hsa-miR-214	CLIP-seq
MIRT826312	hsa-miR-224	CLIP-seq
MIRT826313	hsa-miR-23a	CLIP-seq
MIRT826314	hsa-miR-23b	CLIP-seq
MIRT826315	hsa-miR-23c	CLIP-seq
MIRT826316	hsa-miR-300	CLIP-seq
MIRT826317	hsa-miR-3074-3p	CLIP-seq
MIRT826318	hsa-miR-3123	CLIP-seq
MIRT826319	hsa-miR-3130-5p	CLIP-seq
MIRT826320	hsa-miR-3148	CLIP-seq
MIRT826321	hsa-miR-3157-5p	CLIP-seq
MIRT826322	hsa-miR-34b	CLIP-seq
MIRT826323	hsa-miR-3545-5p	CLIP-seq
MIRT826324	hsa-miR-3591-5p	CLIP-seq
MIRT826325	hsa-miR-3606	CLIP-seq
MIRT826326	hsa-miR-3611	CLIP-seq
MIRT826327	hsa-miR-361-3p	CLIP-seq
MIRT826328	hsa-miR-3619-5p	CLIP-seq
MIRT826329	hsa-miR-3647-5p	CLIP-seq
MIRT826330	hsa-miR-3657	CLIP-seq
MIRT826331	hsa-miR-381	CLIP-seq
MIRT826332	hsa-miR-382	CLIP-seq
MIRT826333	hsa-miR-3941	CLIP-seq
MIRT826334	hsa-miR-409-3p	CLIP-seq
MIRT826335	hsa-miR-4277	CLIP-seq
MIRT826336	hsa-miR-4291	CLIP-seq
MIRT826337	hsa-miR-4460	CLIP-seq
MIRT826338	hsa-miR-4482	CLIP-seq
MIRT826339	hsa-miR-4519	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826341	hsa-miR-466	CLIP-seq
MIRT826342	hsa-miR-4666-3p	CLIP-seq
MIRT826343	hsa-miR-4668-5p	CLIP-seq
MIRT826344	hsa-miR-4672	CLIP-seq
MIRT826345	hsa-miR-4687-3p	CLIP-seq
MIRT826346	hsa-miR-4691-3p	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826347	hsa-miR-4731-3p	CLIP-seq
MIRT826348	hsa-miR-4753-3p	CLIP-seq
MIRT826349	hsa-miR-4768-5p	CLIP-seq
MIRT826350	hsa-miR-4778-5p	CLIP-seq
MIRT826351	hsa-miR-4789-5p	CLIP-seq
MIRT826352	hsa-miR-4801	CLIP-seq
MIRT826353	hsa-miR-498	CLIP-seq
MIRT826354	hsa-miR-542-3p	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT826355	hsa-miR-561	CLIP-seq
MIRT826356	hsa-miR-653	CLIP-seq
MIRT826357	hsa-miR-758	CLIP-seq
MIRT826358	hsa-miR-761	CLIP-seq
MIRT826359	hsa-miR-921	CLIP-seq
MIRT826360	hsa-miR-922	CLIP-seq
MIRT826333	hsa-miR-3941	CLIP-seq
MIRT826341	hsa-miR-466	CLIP-seq
MIRT826344	hsa-miR-4672	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826347	hsa-miR-4731-3p	CLIP-seq
MIRT826352	hsa-miR-4801	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT826264	hsa-miR-106a	CLIP-seq
MIRT826265	hsa-miR-106b	CLIP-seq
MIRT1944337	hsa-miR-124	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT826309	hsa-miR-140-5p	CLIP-seq
MIRT826270	hsa-miR-142-5p	CLIP-seq
MIRT826271	hsa-miR-17	CLIP-seq
MIRT826272	hsa-miR-20a	CLIP-seq
MIRT826273	hsa-miR-20b	CLIP-seq
MIRT826311	hsa-miR-214	CLIP-seq
MIRT826312	hsa-miR-224	CLIP-seq
MIRT1944338	hsa-miR-28-3p	CLIP-seq
MIRT1944339	hsa-miR-297	CLIP-seq
MIRT1944340	hsa-miR-298	CLIP-seq
MIRT1944341	hsa-miR-3117-5p	CLIP-seq
MIRT826319	hsa-miR-3130-5p	CLIP-seq
MIRT1944342	hsa-miR-3144-3p	CLIP-seq
MIRT1944343	hsa-miR-3149	CLIP-seq
MIRT826321	hsa-miR-3157-5p	CLIP-seq
MIRT1944344	hsa-miR-3171	CLIP-seq
MIRT1944345	hsa-miR-335	CLIP-seq
MIRT826277	hsa-miR-338-5p	CLIP-seq
MIRT826278	hsa-miR-340	CLIP-seq
MIRT826323	hsa-miR-3545-5p	CLIP-seq
MIRT826324	hsa-miR-3591-5p	CLIP-seq
MIRT826325	hsa-miR-3606	CLIP-seq
MIRT826279	hsa-miR-3609	CLIP-seq
MIRT826327	hsa-miR-361-3p	CLIP-seq
MIRT826328	hsa-miR-3619-5p	CLIP-seq
MIRT826330	hsa-miR-3657	CLIP-seq
MIRT1944346	hsa-miR-3667-5p	CLIP-seq
MIRT1944347	hsa-miR-3686	CLIP-seq
MIRT1944348	hsa-miR-3714	CLIP-seq
MIRT1944349	hsa-miR-374a	CLIP-seq
MIRT1944350	hsa-miR-374b	CLIP-seq
MIRT1944351	hsa-miR-3910	CLIP-seq
MIRT826282	hsa-miR-410	CLIP-seq
MIRT826336	hsa-miR-4291	CLIP-seq
MIRT826337	hsa-miR-4460	CLIP-seq
MIRT1944352	hsa-miR-4477b	CLIP-seq
MIRT826338	hsa-miR-4482	CLIP-seq
MIRT826339	hsa-miR-4519	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT1944353	hsa-miR-4662a-5p	CLIP-seq
MIRT826346	hsa-miR-4691-3p	CLIP-seq
MIRT826287	hsa-miR-4698	CLIP-seq
MIRT1944354	hsa-miR-4704-5p	CLIP-seq
MIRT826289	hsa-miR-4724-3p	CLIP-seq
MIRT826291	hsa-miR-4796-3p	CLIP-seq
MIRT1944355	hsa-miR-4800-3p	CLIP-seq
MIRT1944356	hsa-miR-488	CLIP-seq
MIRT826353	hsa-miR-498	CLIP-seq
MIRT1944357	hsa-miR-506	CLIP-seq
MIRT1944358	hsa-miR-508-3p	CLIP-seq
MIRT826297	hsa-miR-519d	CLIP-seq
MIRT826299	hsa-miR-548ah	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT826358	hsa-miR-761	CLIP-seq
MIRT1944359	hsa-miR-769-5p	CLIP-seq
MIRT1944360	hsa-miR-875-5p	CLIP-seq
MIRT826359	hsa-miR-921	CLIP-seq
MIRT826360	hsa-miR-922	CLIP-seq
MIRT826305	hsa-miR-93	CLIP-seq
MIRT826266	hsa-miR-1237	CLIP-seq
MIRT2182913	hsa-miR-1245b-3p	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826307	hsa-miR-1257	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT826269	hsa-miR-1283	CLIP-seq
MIRT2182914	hsa-miR-135a	CLIP-seq
MIRT2182915	hsa-miR-135b	CLIP-seq
MIRT826309	hsa-miR-140-5p	CLIP-seq
MIRT2182916	hsa-miR-141	CLIP-seq
MIRT826270	hsa-miR-142-5p	CLIP-seq
MIRT2182917	hsa-miR-1827	CLIP-seq
MIRT2182918	hsa-miR-194	CLIP-seq
MIRT2182919	hsa-miR-200a	CLIP-seq
MIRT2182920	hsa-miR-204	CLIP-seq
MIRT2182921	hsa-miR-211	CLIP-seq
MIRT826310	hsa-miR-2113	CLIP-seq
MIRT826311	hsa-miR-214	CLIP-seq
MIRT2182922	hsa-miR-2278	CLIP-seq
MIRT826313	hsa-miR-23a	CLIP-seq
MIRT826314	hsa-miR-23b	CLIP-seq
MIRT826315	hsa-miR-23c	CLIP-seq
MIRT826317	hsa-miR-3074-3p	CLIP-seq
MIRT2182923	hsa-miR-30a	CLIP-seq
MIRT2182924	hsa-miR-30b	CLIP-seq
MIRT2182925	hsa-miR-30c	CLIP-seq
MIRT2182926	hsa-miR-30d	CLIP-seq
MIRT2182927	hsa-miR-30e	CLIP-seq
MIRT826274	hsa-miR-3128	CLIP-seq
MIRT826319	hsa-miR-3130-5p	CLIP-seq
MIRT826321	hsa-miR-3157-5p	CLIP-seq
MIRT2182928	hsa-miR-323-3p	CLIP-seq
MIRT826275	hsa-miR-326	CLIP-seq
MIRT826276	hsa-miR-330-5p	CLIP-seq
MIRT1944345	hsa-miR-335	CLIP-seq
MIRT2182929	hsa-miR-337-3p	CLIP-seq
MIRT826278	hsa-miR-340	CLIP-seq
MIRT826323	hsa-miR-3545-5p	CLIP-seq
MIRT826324	hsa-miR-3591-5p	CLIP-seq
MIRT826325	hsa-miR-3606	CLIP-seq
MIRT826326	hsa-miR-3611	CLIP-seq
MIRT826327	hsa-miR-361-3p	CLIP-seq
MIRT826328	hsa-miR-3619-5p	CLIP-seq
MIRT826280	hsa-miR-362-5p	CLIP-seq
MIRT826329	hsa-miR-3647-5p	CLIP-seq
MIRT2182930	hsa-miR-3655	CLIP-seq
MIRT826330	hsa-miR-3657	CLIP-seq
MIRT826333	hsa-miR-3941	CLIP-seq
MIRT826281	hsa-miR-3945	CLIP-seq
MIRT826334	hsa-miR-409-3p	CLIP-seq
MIRT826283	hsa-miR-4253	CLIP-seq
MIRT826335	hsa-miR-4277	CLIP-seq
MIRT826336	hsa-miR-4291	CLIP-seq
MIRT826284	hsa-miR-4427	CLIP-seq
MIRT826337	hsa-miR-4460	CLIP-seq
MIRT826338	hsa-miR-4482	CLIP-seq
MIRT2182931	hsa-miR-4506	CLIP-seq
MIRT826339	hsa-miR-4519	CLIP-seq
MIRT2182932	hsa-miR-4637	CLIP-seq
MIRT2182933	hsa-miR-4646-3p	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826341	hsa-miR-466	CLIP-seq
MIRT826344	hsa-miR-4672	CLIP-seq
MIRT826286	hsa-miR-4684-5p	CLIP-seq
MIRT826345	hsa-miR-4687-3p	CLIP-seq
MIRT826346	hsa-miR-4691-3p	CLIP-seq
MIRT826288	hsa-miR-4720-5p	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826347	hsa-miR-4731-3p	CLIP-seq
MIRT826348	hsa-miR-4753-3p	CLIP-seq
MIRT826292	hsa-miR-4799-3p	CLIP-seq
MIRT1944355	hsa-miR-4800-3p	CLIP-seq
MIRT826352	hsa-miR-4801	CLIP-seq
MIRT826293	hsa-miR-487a	CLIP-seq
MIRT826295	hsa-miR-500b	CLIP-seq
MIRT826296	hsa-miR-501-5p	CLIP-seq
MIRT2182934	hsa-miR-515-5p	CLIP-seq
MIRT2182935	hsa-miR-520d-5p	CLIP-seq
MIRT2182936	hsa-miR-524-5p	CLIP-seq
MIRT826354	hsa-miR-542-3p	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT2182937	hsa-miR-556-3p	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT2182938	hsa-miR-591	CLIP-seq
MIRT2182939	hsa-miR-604	CLIP-seq
MIRT2182940	hsa-miR-615-5p	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT2182941	hsa-miR-647	CLIP-seq
MIRT826356	hsa-miR-653	CLIP-seq
MIRT826357	hsa-miR-758	CLIP-seq
MIRT826358	hsa-miR-761	CLIP-seq
MIRT1944359	hsa-miR-769-5p	CLIP-seq
MIRT826359	hsa-miR-921	CLIP-seq
MIRT826360	hsa-miR-922	CLIP-seq
MIRT826306	hsa-miR-942	CLIP-seq
MIRT826266	hsa-miR-1237	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826280	hsa-miR-362-5p	CLIP-seq
MIRT826295	hsa-miR-500b	CLIP-seq
MIRT826296	hsa-miR-501-5p	CLIP-seq
MIRT2182914	hsa-miR-135a	CLIP-seq
MIRT2182915	hsa-miR-135b	CLIP-seq
MIRT2182920	hsa-miR-204	CLIP-seq
MIRT2182921	hsa-miR-211	CLIP-seq
MIRT2182930	hsa-miR-3655	CLIP-seq
MIRT2182933	hsa-miR-4646-3p	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT2182939	hsa-miR-604	CLIP-seq
MIRT2182941	hsa-miR-647	CLIP-seq
MIRT2676074	hsa-miR-1229	CLIP-seq
MIRT1944337	hsa-miR-124	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT1944340	hsa-miR-298	CLIP-seq
MIRT826274	hsa-miR-3128	CLIP-seq
MIRT826275	hsa-miR-326	CLIP-seq
MIRT826276	hsa-miR-330-5p	CLIP-seq
MIRT2676075	hsa-miR-3607-3p	CLIP-seq
MIRT2676076	hsa-miR-3659	CLIP-seq
MIRT1944347	hsa-miR-3686	CLIP-seq
MIRT1944348	hsa-miR-3714	CLIP-seq
MIRT1944351	hsa-miR-3910	CLIP-seq
MIRT826281	hsa-miR-3945	CLIP-seq
MIRT2676077	hsa-miR-409-5p	CLIP-seq
MIRT826283	hsa-miR-4253	CLIP-seq
MIRT826284	hsa-miR-4427	CLIP-seq
MIRT1944352	hsa-miR-4477b	CLIP-seq
MIRT2676078	hsa-miR-4641	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826287	hsa-miR-4698	CLIP-seq
MIRT826288	hsa-miR-4720-5p	CLIP-seq
MIRT826348	hsa-miR-4753-3p	CLIP-seq
MIRT2676079	hsa-miR-4775	CLIP-seq
MIRT2676080	hsa-miR-4797-5p	CLIP-seq
MIRT826292	hsa-miR-4799-3p	CLIP-seq
MIRT826293	hsa-miR-487a	CLIP-seq
MIRT826294	hsa-miR-495	CLIP-seq
MIRT1944357	hsa-miR-506	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT2676081	hsa-miR-590-3p	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT2676082	hsa-miR-759	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000932	Component	P-body	IBA	21873635
GO:0000932	Component	P-body	IDA	12878161
GO:0005515	Function	Protein binding	IPI	12878161, 18305892, 21145461, 22761572, 32296183, 32814053
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	TAS
GO:0007517	Process	Muscle organ development	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0022008	Process	Neurogenesis	IBA	21873635
GO:0032991	Component	Protein-containing complex	IDA
GO:0036464	Component	Cytoplasmic ribonucleoprotein granule	IDA
GO:0042802	Function	Identical protein binding	IPI	32296183
GO:0043393	Process	Regulation of protein binding	NAS	11179693
GO:0043687	Process	Post-translational protein modification	TAS
GO:0097602	Function	Cullin family protein binding	IPI	14528312

Other IDs

• MIM: 608530
• HGNC: 1120
• e!Ensembl: ENSG00000064726

Protein

• UniProt ID: Q9H0C5
• Protein name: BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)
• Protein function: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312). Seems to regulate expression levels and/or subnuclear di
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	59 → 175	BTB/POZ domain	Domain
  PF07707	BACK	180 → 287	BTB And C-terminal Kelch	Domain
  PF08005	PHR	333 → 481	PHR domain	Domain

• Sequence:

  MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFA
  FLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIE
  LPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNA
  FMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRL
  FGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREV
  VNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRIS
  IVGFGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPN
  VCYTACATLKGPDSHYGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSIEDGQIPEIIF
  YT

• Sequence length: 482

Pathways

Reactome:

Neddylation
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Chronic obstructive pulmonary disease	Chronic Obstructive Airway Disease	rs2227956, rs1008438, rs1043618, rs562047, rs1061581, rs2763979, rs6457452, rs13147758, rs1828591, rs13118928	30804561