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PALS2 (protein associated with LIN7 2, MAGUK p55 family member)
Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51678
Gene nameGene Name - the full gene name approved by the HGNC.
Protein associated with LIN7 2, MAGUK p55 family member
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
PALS2
SynonymsGene synonyms aliases
MPP6, VAM-1, VAM1, p55T
ChromosomeChromosome number
7
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p15.3
SummarySummary of gene provided in NCBI Entrez Gene.
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling protei
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 11311936, 24366813, 28514442, 32296183
GO:0005886 Component Plasma membrane IEA
GO:0016020 Component Membrane NAS 11311936
GO:0065003 Process Protein-containing complex assembly NAS 11311936
GO:0070062 Component Extracellular exosome HDA 20458337
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9NZW5
Protein name Protein PALS2 (MAGUK p55 subfamily member 6) (Membrane protein, palmitoylated 6) (Veli-associated MAGUK 1) (VAM-1)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02828 L27
1 → 54
L27 domain
 Domain
PF02828 L27
57 → 109
L27 domain
 Domain
PF00595 PDZ
131 → 206
PDZ domain
 Domain
PF07653 SH3_2
219 → 282
Variant SH3 domain
 Domain
PF00625 Guanylate_kin
337 → 527
Guanylate kinase
 Domain
Sequence
Sequence length 540
Interactions View interactions
Associated diseases
Gene Gene ontology Other IDs Protein Associated diseases
Causal
Disease name Disease term dbSNP ID References
Attention deficit hyperactivity disorder Attention deficit hyperactivity disorder rs120074176, rs786205019 23453885
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 23453885, 31374203
Unknown
Disease name Disease term dbSNP ID References
Bipolar disorder Bipolar Disorder 23453885
Development disorder Child Development Disorders, Pervasive 23453885
Mental depression Major Depressive Disorder rs587778876, rs587778877 23453885

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