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RAB14 (RAB14, member RAS oncogene family)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51552
Gene nameGene Name - the full gene name approved by the HGNC.
RAB14, member RAS oncogene family
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
RAB14
SynonymsGene synonyms aliases
FBP, RAB-14
ChromosomeChromosome number
9
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q33.2
SummarySummary of gene provided in NCBI Entrez Gene.
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Reporter assay 21358675
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0003924 Function GTPase activity IBA 21873635
GO:0003924 Function GTPase activity IDA 16034420, 17562788
GO:0003924 Function GTPase activity NAS 15004230
GO:0005515 Function Protein binding IPI 16034420, 16237761, 16902405, 25416956, 32296183
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P61106
Protein name Ras-related protein Rab-14 (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r
PDB 1Z0F , 4D0G , 4DRZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras
13 174
Ras family
Domain
Sequence
Sequence length 215
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  Efferocytosis
AMPK signaling pathway
  Synthesis of PIPs at the plasma membrane
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Rheumatoid arthritis Rheumatoid Arthritis rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212 19503088

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