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KLHL5 (kelch like family member 5)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51088
Gene nameGene Name - the full gene name approved by the HGNC.
Kelch like family member 5
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
KLHL5
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
4
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4p14
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018473 hsa-miR-335-5p Microarray 18185580
MIRT020925 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT724517 hsa-miR-4517 HITS-CLIP 19536157
MIRT724516 hsa-miR-5583-3p HITS-CLIP 19536157
MIRT724515 hsa-miR-3127-3p HITS-CLIP 19536157
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0003779 Function Actin binding IEA
GO:0005515 Function Protein binding IPI 21145461, 21988832
GO:0005737 Component Cytoplasm NAS 14672410
GO:0005829 Component Cytosol TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q96PQ7
Protein name Kelch-like protein 5
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00651 BTB
210 317
BTB/POZ domain
Domain
PF07707 BACK
322 423
BTB And C-terminal Kelch
Domain
PF01344 Kelch_1
467 501
Kelch motif
Repeat
PF01344 Kelch_1
503 548
Kelch motif
Repeat
PF01344 Kelch_1
550 595
Kelch motif
Repeat
PF01344 Kelch_1
597 642
Kelch motif
Repeat
PF01344 Kelch_1
644 695
Kelch motif
Repeat
PF01344 Kelch_1
697 741
Kelch motif
Repeat
Sequence
Sequence length 755
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Asthma Childhood asthma rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 23829686

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