GediPNet logo

MIR425 (microRNA 425)
Gene
Gene Gene ontology Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
494337
Gene nameGene Name - the full gene name approved by the HGNC.
MicroRNA 425
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
MIR425
SynonymsGene synonyms aliases
MIRN425, hsa-mir-425, mir-425
ChromosomeChromosome number
3
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p21.31
SummarySummary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space HDA 26646931
GO:0035195 Process Gene silencing by miRNA IDA 27185878
GO:0035195 Process Gene silencing by miRNA IEA
GO:0035195 Process Gene silencing by miRNA IGI 27185878
GO:1903231 Function MRNA binding involved in posttranscriptional gene silencing IDA 27185878
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Associated diseases
MIM
HGNC
e!Ensembl
Interactions View interactions
Associated diseases
Gene Gene ontology Other IDs Associated diseases
Causal
Disease name Disease term dbSNP ID References
Pulmonary fibrosis Pulmonary Fibrosis rs121918666, rs199422300, rs121917737, rs121917834, rs199422294, rs201159197, rs199422297, rs199422305, rs751381953, rs876661305, rs878853260, rs863223336, rs786205702, rs1555811762, rs1060502990, rs1555903332, rs1554038539, rs1554042899, rs938938578 25926378
Unknown
Disease name Disease term dbSNP ID References
Adenoma Adenoma, Adenoma, Basal Cell, Follicular adenoma, Adenoma, Microcystic, Adenoma, Monomorphic, Adenoma, Trabecular 25926378
Alveolitis Alveolitis, Fibrosing 25926378
Papillary adenoma Papillary adenoma 25926378

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412