Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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4883 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Natriuretic peptide receptor 3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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NPR3 |
SynonymsGene synonyms aliases
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ANP-C, ANPR-C, ANPRC, BOMOS, C5orf23, GUCY2B, NPR-C, NPRC |
ChromosomeChromosome number
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5 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5p13.3 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of thi |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
P17342 |
Protein name |
Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C) |
Protein function |
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB |
PDB |
1JDN
,
1JDP
,
1YK0
,
1YK1
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF01094 |
ANF_receptor |
71 → 425 |
Receptor family ligand binding region |
Family |
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Sequence |
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Sequence length |
541 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
19208208 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Arachnodactyly |
Arachnodactyly |
|
10468599 |
Prostatic neoplasms |
Prostatic Neoplasms |
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19208208 |
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