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ATP1B2 (ATPase Na+/K+ transporting subunit beta 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
482
Gene nameGene Name - the full gene name approved by the HGNC.
ATPase Na+/K+ transporting subunit beta 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ATP1B2
SynonymsGene synonyms aliases
AMOG
ChromosomeChromosome number
17
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17p13.1
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemica
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019110 hsa-miR-335-5p Microarray 18185580
MIRT807060 hsa-miR-1262 CLIP-seq
MIRT807061 hsa-miR-1273 CLIP-seq
MIRT807062 hsa-miR-1285 CLIP-seq
MIRT807063 hsa-miR-1293 CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001671 Function ATPase activator activity IBA 21873635
GO:0001671 Function ATPase activator activity IDA 10636900, 19542013
GO:0001895 Process Retina homeostasis ISS
GO:0001917 Component Photoreceptor inner segment ISS
GO:0005515 Function Protein binding IPI 11027149
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P14415
Protein name Sodium/potassium-transporting ATPase subunit beta-2 (Adhesion molecule in glia) (AMOG) (Sodium/potassium-dependent ATPase subunit beta-2)
Protein function This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known.; Mediat
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00287 Na_K-ATPase
7 283
Sodium / potassium ATPase beta chain
Family
Sequence
Sequence length 290
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  cGMP-PKG signaling pathway
cAMP signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Cytoskeleton in muscle cells
Insulin secretion
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Aldosterone synthesis and secretion
Aldosterone-regulated sodium reabsorption
Endocrine and other factor-regulated calcium reabsorption
Proximal tubule bicarbonate reclamation
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Carbohydrate digestion and absorption
Protein digestion and absorption
Bile secretion
Mineral absorption
  Basigin interactions
Ion homeostasis
Ion transport by P-type ATPases
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Esophagus neoplasm Squamous cell carcinoma of esophagus rs28934578, rs121918714, rs1567556006, rs1575166666 25129146
Glioma Glioma, mixed gliomas, Malignant Glioma rs121909219, rs121909224, rs587776667, rs587776671, rs121909239, rs121909241, rs28933368, rs121913500, rs55863639, rs786201995, rs786202517, rs786201044, rs398123317, rs1057518425, rs121913499, rs1060500122, rs781647403, rs1060500126, rs1554897889, rs1114167629, rs1114167656, rs587782603, rs1554893824, rs1554900615, rs1564568660, rs786204900, rs762518389, rs1339631701 16865689

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