MX1 (MX dynamin like GTPase 1)

Gene

• Entrez ID: 4599
• Gene name: MX dynamin like GTPase 1
• Gene symbol: MX1
• Synonyms: IFI-78K, IFI78, MX, MxA, lncMX1-215
• Chromosome: 21
• Chromosome location: 21q22.3
• Summary: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA a

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT734368	hsa-miR-221-3p	ELISA, Luciferase reporter assay, RNA-seq, Western blotting	32209695
MIRT734369	hsa-miR-125b-5p	ELISA, Luciferase reporter assay, RNA-seq, Western blotting	32209695
MIRT2575804	hsa-miR-1292	CLIP-seq
MIRT2575805	hsa-miR-1324	CLIP-seq
MIRT2575806	hsa-miR-141	CLIP-seq
MIRT2575807	hsa-miR-1825	CLIP-seq
MIRT2575808	hsa-miR-188-5p	CLIP-seq
MIRT2575809	hsa-miR-191	CLIP-seq
MIRT2575810	hsa-miR-1910	CLIP-seq
MIRT2575811	hsa-miR-197	CLIP-seq
MIRT2575812	hsa-miR-199a-5p	CLIP-seq
MIRT2575813	hsa-miR-199b-5p	CLIP-seq
MIRT2575814	hsa-miR-200a	CLIP-seq
MIRT2575815	hsa-miR-204	CLIP-seq
MIRT2575816	hsa-miR-205	CLIP-seq
MIRT2575817	hsa-miR-210	CLIP-seq
MIRT2575818	hsa-miR-211	CLIP-seq
MIRT2575819	hsa-miR-223	CLIP-seq
MIRT2575820	hsa-miR-2276	CLIP-seq
MIRT2575821	hsa-miR-3074-5p	CLIP-seq
MIRT2575822	hsa-miR-3120-5p	CLIP-seq
MIRT2575823	hsa-miR-3146	CLIP-seq
MIRT2575824	hsa-miR-3151	CLIP-seq
MIRT2575825	hsa-miR-3154	CLIP-seq
MIRT2575826	hsa-miR-3163	CLIP-seq
MIRT2575827	hsa-miR-3166	CLIP-seq
MIRT2575828	hsa-miR-3175	CLIP-seq
MIRT2575829	hsa-miR-3179	CLIP-seq
MIRT2575830	hsa-miR-3200-5p	CLIP-seq
MIRT2575831	hsa-miR-320e	CLIP-seq
MIRT2575832	hsa-miR-340	CLIP-seq
MIRT2575833	hsa-miR-342-3p	CLIP-seq
MIRT2575834	hsa-miR-345	CLIP-seq
MIRT2575835	hsa-miR-3607-5p	CLIP-seq
MIRT2575836	hsa-miR-3611	CLIP-seq
MIRT2575837	hsa-miR-3616-3p	CLIP-seq
MIRT2575838	hsa-miR-3647-3p	CLIP-seq
MIRT2575839	hsa-miR-3662	CLIP-seq
MIRT2575840	hsa-miR-3663-3p	CLIP-seq
MIRT2575841	hsa-miR-370	CLIP-seq
MIRT2575842	hsa-miR-3915	CLIP-seq
MIRT2575843	hsa-miR-3919	CLIP-seq
MIRT2575844	hsa-miR-3928	CLIP-seq
MIRT2575845	hsa-miR-4258	CLIP-seq
MIRT2575846	hsa-miR-4267	CLIP-seq
MIRT2575847	hsa-miR-4268	CLIP-seq
MIRT2575848	hsa-miR-4283	CLIP-seq
MIRT2575849	hsa-miR-4291	CLIP-seq
MIRT2575850	hsa-miR-4302	CLIP-seq
MIRT2575851	hsa-miR-4303	CLIP-seq
MIRT2575852	hsa-miR-4310	CLIP-seq
MIRT2575853	hsa-miR-4328	CLIP-seq
MIRT2575854	hsa-miR-4446-3p	CLIP-seq
MIRT2575855	hsa-miR-4448	CLIP-seq
MIRT2575856	hsa-miR-4475	CLIP-seq
MIRT2575857	hsa-miR-4489	CLIP-seq
MIRT2575858	hsa-miR-4492	CLIP-seq
MIRT2575859	hsa-miR-4498	CLIP-seq
MIRT2575860	hsa-miR-4508	CLIP-seq
MIRT2575861	hsa-miR-4528	CLIP-seq
MIRT2575862	hsa-miR-455-3p	CLIP-seq
MIRT2575863	hsa-miR-4649-3p	CLIP-seq
MIRT2575864	hsa-miR-4656	CLIP-seq
MIRT2575865	hsa-miR-4668-3p	CLIP-seq
MIRT2575866	hsa-miR-4679	CLIP-seq
MIRT2575867	hsa-miR-4697-3p	CLIP-seq
MIRT2575868	hsa-miR-4708-3p	CLIP-seq
MIRT2575869	hsa-miR-4712-5p	CLIP-seq
MIRT2575870	hsa-miR-4721	CLIP-seq
MIRT2575871	hsa-miR-4761-5p	CLIP-seq
MIRT2575872	hsa-miR-4797-5p	CLIP-seq
MIRT2575873	hsa-miR-486-3p	CLIP-seq
MIRT2575874	hsa-miR-516a-3p	CLIP-seq
MIRT2575875	hsa-miR-548c-3p	CLIP-seq
MIRT2575876	hsa-miR-558	CLIP-seq
MIRT2575877	hsa-miR-592	CLIP-seq
MIRT2575878	hsa-miR-597	CLIP-seq
MIRT2575879	hsa-miR-605	CLIP-seq
MIRT2575880	hsa-miR-622	CLIP-seq
MIRT2575881	hsa-miR-629	CLIP-seq
MIRT2575882	hsa-miR-648	CLIP-seq
MIRT2575883	hsa-miR-758	CLIP-seq
MIRT2575884	hsa-miR-760	CLIP-seq
MIRT2575885	hsa-miR-762	CLIP-seq
MIRT2575886	hsa-miR-770-5p	CLIP-seq
MIRT2575887	hsa-miR-941	CLIP-seq
MIRT2575804	hsa-miR-1292	CLIP-seq
MIRT2575805	hsa-miR-1324	CLIP-seq
MIRT2575806	hsa-miR-141	CLIP-seq
MIRT2575807	hsa-miR-1825	CLIP-seq
MIRT2575808	hsa-miR-188-5p	CLIP-seq
MIRT2575809	hsa-miR-191	CLIP-seq
MIRT2575810	hsa-miR-1910	CLIP-seq
MIRT2575811	hsa-miR-197	CLIP-seq
MIRT2575812	hsa-miR-199a-5p	CLIP-seq
MIRT2575813	hsa-miR-199b-5p	CLIP-seq
MIRT2575814	hsa-miR-200a	CLIP-seq
MIRT2575815	hsa-miR-204	CLIP-seq
MIRT2575816	hsa-miR-205	CLIP-seq
MIRT2575817	hsa-miR-210	CLIP-seq
MIRT2575818	hsa-miR-211	CLIP-seq
MIRT2575819	hsa-miR-223	CLIP-seq
MIRT2575820	hsa-miR-2276	CLIP-seq
MIRT2575821	hsa-miR-3074-5p	CLIP-seq
MIRT2575822	hsa-miR-3120-5p	CLIP-seq
MIRT2575823	hsa-miR-3146	CLIP-seq
MIRT2575824	hsa-miR-3151	CLIP-seq
MIRT2575825	hsa-miR-3154	CLIP-seq
MIRT2575826	hsa-miR-3163	CLIP-seq
MIRT2575827	hsa-miR-3166	CLIP-seq
MIRT2575828	hsa-miR-3175	CLIP-seq
MIRT2575829	hsa-miR-3179	CLIP-seq
MIRT2575830	hsa-miR-3200-5p	CLIP-seq
MIRT2575831	hsa-miR-320e	CLIP-seq
MIRT2575832	hsa-miR-340	CLIP-seq
MIRT2575833	hsa-miR-342-3p	CLIP-seq
MIRT2575834	hsa-miR-345	CLIP-seq
MIRT2575835	hsa-miR-3607-5p	CLIP-seq
MIRT2575836	hsa-miR-3611	CLIP-seq
MIRT2575837	hsa-miR-3616-3p	CLIP-seq
MIRT2575838	hsa-miR-3647-3p	CLIP-seq
MIRT2685562	hsa-miR-3652	CLIP-seq
MIRT2575839	hsa-miR-3662	CLIP-seq
MIRT2575840	hsa-miR-3663-3p	CLIP-seq
MIRT2575841	hsa-miR-370	CLIP-seq
MIRT2575842	hsa-miR-3915	CLIP-seq
MIRT2575843	hsa-miR-3919	CLIP-seq
MIRT2575844	hsa-miR-3928	CLIP-seq
MIRT2575845	hsa-miR-4258	CLIP-seq
MIRT2575846	hsa-miR-4267	CLIP-seq
MIRT2575847	hsa-miR-4268	CLIP-seq
MIRT2575848	hsa-miR-4283	CLIP-seq
MIRT2575849	hsa-miR-4291	CLIP-seq
MIRT2575850	hsa-miR-4302	CLIP-seq
MIRT2575851	hsa-miR-4303	CLIP-seq
MIRT2575852	hsa-miR-4310	CLIP-seq
MIRT2575853	hsa-miR-4328	CLIP-seq
MIRT2685563	hsa-miR-4430	CLIP-seq
MIRT2575854	hsa-miR-4446-3p	CLIP-seq
MIRT2575855	hsa-miR-4448	CLIP-seq
MIRT2575856	hsa-miR-4475	CLIP-seq
MIRT2575857	hsa-miR-4489	CLIP-seq
MIRT2575858	hsa-miR-4492	CLIP-seq
MIRT2575859	hsa-miR-4498	CLIP-seq
MIRT2575860	hsa-miR-4508	CLIP-seq
MIRT2685564	hsa-miR-4520a-3p	CLIP-seq
MIRT2575861	hsa-miR-4528	CLIP-seq
MIRT2575862	hsa-miR-455-3p	CLIP-seq
MIRT2685565	hsa-miR-4638-3p	CLIP-seq
MIRT2575863	hsa-miR-4649-3p	CLIP-seq
MIRT2575864	hsa-miR-4656	CLIP-seq
MIRT2575865	hsa-miR-4668-3p	CLIP-seq
MIRT2575866	hsa-miR-4679	CLIP-seq
MIRT2575867	hsa-miR-4697-3p	CLIP-seq
MIRT2575868	hsa-miR-4708-3p	CLIP-seq
MIRT2575869	hsa-miR-4712-5p	CLIP-seq
MIRT2575870	hsa-miR-4721	CLIP-seq
MIRT2575871	hsa-miR-4761-5p	CLIP-seq
MIRT2575872	hsa-miR-4797-5p	CLIP-seq
MIRT2575873	hsa-miR-486-3p	CLIP-seq
MIRT2575874	hsa-miR-516a-3p	CLIP-seq
MIRT2575875	hsa-miR-548c-3p	CLIP-seq
MIRT2575876	hsa-miR-558	CLIP-seq
MIRT2575877	hsa-miR-592	CLIP-seq
MIRT2575878	hsa-miR-597	CLIP-seq
MIRT2575879	hsa-miR-605	CLIP-seq
MIRT2575880	hsa-miR-622	CLIP-seq
MIRT2575881	hsa-miR-629	CLIP-seq
MIRT2575882	hsa-miR-648	CLIP-seq
MIRT2575883	hsa-miR-758	CLIP-seq
MIRT2575884	hsa-miR-760	CLIP-seq
MIRT2575885	hsa-miR-762	CLIP-seq
MIRT2575886	hsa-miR-770-5p	CLIP-seq
MIRT2575887	hsa-miR-941	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
CREB5	Activation	21132541

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000266	Process	Mitochondrial fission	IBA	21873635
GO:0003374	Process	Dynamin family protein polymerization involved in mitochondrial fission	IBA	21873635
GO:0003924	Function	GTPase activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	15047845, 15757897, 21859714, 25416956, 30833792, 32296183
GO:0005525	Function	GTP binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	21859714
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005829	Component	Cytosol	HDA	16780588
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0006915	Process	Apoptotic process	TAS	9389754
GO:0006952	Process	Defense response	TAS	2154602
GO:0007165	Process	Signal transduction	TAS	9389754
GO:0008017	Function	Microtubule binding	IBA	21873635
GO:0009615	Process	Response to virus	IMP	15047845
GO:0014069	Component	Postsynaptic density	IBA	21873635
GO:0015630	Component	Microtubule cytoskeleton	IBA	21873635
GO:0016020	Component	Membrane	IBA	21873635
GO:0016185	Process	Synaptic vesicle budding from presynaptic endocytic zone membrane	IBA	21873635
GO:0030424	Component	Axon	IBA	21873635
GO:0031410	Component	Cytoplasmic vesicle	IBA	21873635
GO:0031623	Process	Receptor internalization	IBA	21873635
GO:0031965	Component	Nuclear membrane	IDA
GO:0031966	Component	Mitochondrial membrane	IBA	21873635
GO:0034340	Process	Response to type I interferon	TAS	21859714
GO:0042802	Function	Identical protein binding	IPI	20428112, 25295396, 25416956, 32296183
GO:0044327	Component	Dendritic spine head	IBA	21873635
GO:0045071	Process	Negative regulation of viral genome replication	IDA	14687945, 15047845, 16202617
GO:0045087	Process	Innate immune response	TAS	16202617
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	15047845
GO:0050803	Process	Regulation of synapse structure or activity	IBA	21873635
GO:0051607	Process	Defense response to virus	IDA	21478870
GO:0060337	Process	Type I interferon signaling pathway	TAS
GO:0061025	Process	Membrane fusion	IBA	21873635
GO:0098793	Component	Presynapse	IEA
GO:0098844	Component	Postsynaptic endocytic zone membrane	IBA	21873635
GO:0098884	Process	Postsynaptic neurotransmitter receptor internalization	IBA	21873635

Other IDs

• MIM: 147150
• HGNC: 7532
• e!Ensembl: ENSG00000157601

Protein

• UniProt ID: P20591
• Protein name: Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding pr
• Protein function: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid.
• PDB: 3LJB, 3SZR, 3ZYS, 4P4S, 4P4T, 4P4U, 5GTM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00350	Dynamin_N	73 → 249	Dynamin family	Domain
  PF01031	Dynamin_M	260 → 547	Dynamin central region	Family
  PF02212	GED	569 → 660	Dynamin GTPase effector domain	Family

• Sequence:

  MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR
  ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW
  RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP
  GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD
  RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK
  IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY
  GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN
  NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV
  RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG
  ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII
  QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF
  PG

• Sequence length: 662

Pathways

KEGG:

Viral life cycle - HIV-1
Hepatitis C
Measles
Influenza A
Human papillomavirus infection
Coronavirus disease - COVID-19

Reactome:

ISG15 antiviral mechanism
Interferon alpha/beta signaling

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Fanconi anemia	Fanconi Anemia	rs121918164, rs118203997, rs118203998, rs118203999, rs397507552, rs778507965, rs747851434, rs587776570, rs121907930, rs794726660, rs137852986, rs730880277, rs730880278, rs104894221, rs587778340, rs104894222, rs121434425, rs200479612, rs121434426, rs397507561, rs149616199, rs397507560, rs587776640, rs267606998, rs267606999, rs121434505, rs121434506, rs878854342, rs80359550, rs80359604, rs80359070, rs80358695, rs80358979, rs80359180, rs81002897, rs81002899, rs1569085810, rs121917786, rs121917787, rs121917788, rs104886458, rs121917783, rs104886456, rs121917784, rs104886457, rs794726667, rs104886459, rs121917785, rs794726668, rs149364097, rs1596534281, rs1218169126, rs773642409, rs1567178071, rs387907159, rs1569083185, rs1569083464, rs80359271, rs80359507, rs28897743, rs397507404, rs397507553, rs397507559, rs80358533, rs276174859, rs80359024, rs55770810, rs397509400, rs149364215, rs397509401, rs397509402, rs80359161, rs80359773, rs515726073, rs180177143, rs180177112, rs180177113, rs180177126, rs180177133, rs180177135, rs180177085, rs180177092, rs587779904, rs587779909, rs587780224, rs587780228, rs587778134, rs587780240, rs587781410, rs587780259, rs148100796, rs587778319, rs587778337, rs587778345, rs587777945, rs587776416, rs587780840, rs587781287, rs200293302, rs587781416, rs587781490, rs587781655, rs368796923, rs587776410, rs587781985, rs587781995, rs587782036, rs587782170, rs574552037, rs587782410, rs180177110, rs587782528, rs587782533, rs587782699, rs587782702, rs587782818, rs587783028, rs730881710, rs730881709, rs730881708, rs730881731, rs730881619, rs730881876, rs730881879, rs730881942, rs730881939, rs730881940, rs730881931, rs730881941, rs730881933, rs730881649, rs786203488, rs786203945, rs786202563, rs786201909, rs587782286, rs770637624, rs786203384, rs775537066, rs747604569, rs763009188, rs786204205, rs786204246, rs756367276, rs786204204, rs786204238, rs774209201, rs781542763, rs377294947, rs752160950, rs774357609, rs796052212, rs879255255, rs747622521, rs772359099, rs797045116, rs375656231, rs762902309, rs869320684, rs869320685, rs797045175, rs797045570, rs863224506, rs863224441, rs863224827, rs780825099, rs779582317, rs775171520, rs371897078, rs766105286, rs770318990, rs864622739, rs747892390, rs149277003, rs864622188, rs864622187, rs864622611, rs864622277, rs869312763, rs762128147, rs876658813, rs747148023, rs757128712, rs767796996, rs876659497, rs876658644, rs760235677, rs876658652, rs876659874, rs759292615, rs771654971, rs775735278, rs769039987, rs878855046, rs766567785, rs145394391, rs878853671, rs878854181, rs878855162, rs574034197, rs878853663, rs878853660, rs759877008, rs878855177, rs760551339, rs878855143, rs755471995, rs879254329, rs587780653, rs886038169, rs886038189, rs370510954, rs761988162, rs529201454, rs886063898, rs760412752, rs867319477, rs1057516455, rs1057517170, rs1057516488, rs1057516963, rs1057516298, rs944083227, rs1057516313, rs1057516919, rs1057516248, rs1057516792, rs1057517125, rs1057517203, rs1057516917, rs1057516247, rs1057516291, rs1057516384, rs1057517219, rs1057517147, rs1057517131, rs868273545, rs372163487, rs1057516430, rs773159223, rs1057517641, rs1057517643, rs1057517648, rs1057519413, rs1057517812, rs112832879, rs1057521855, rs1060499823, rs774170058, rs1060501862, rs1554842611, rs745495865, rs147021911, rs758597713, rs769248873, rs1060501900, rs1060501878, rs755546887, rs1060501879, rs1060502748, rs1060501880, rs1060501876, rs555449842, rs1060502605, rs1060502601, rs774586107, rs768793789, rs1060499606, rs754850404, rs759900071, rs1064795597, rs776054094, rs1057519366, rs753211631, rs754367349, rs182657062, rs1553608812, rs1188581065, rs1555547474, rs1555548428, rs149551759, rs772751654, rs780020495, rs773906241, rs368728266, rs769547477, rs756140957, rs1555603011, rs1553435610, rs1554829415, rs1554829441, rs1554833186, rs1166587869, rs1447482674, rs781479923, rs777825824, rs752720263, rs1432988639, rs1555536446, rs1555538740, rs1343140664, rs759899153, rs764122657, rs1555593715, rs1338138752, rs1555594864, rs1555605074, rs1555602141, rs1555593616, rs774684620, rs754929230, rs776529713, rs746993675, rs1555594912, rs1327086366, rs145310733, rs1555599288, rs1555593450, rs1413872299, rs1555605103, rs748589398, rs786202760, rs1555607022, rs1555593670, rs1555594590, rs1555602159, rs1555591308, rs539460201, rs774949203, rs1555286294, rs1028347439, rs1555603056, rs1484503633, rs1555429629, rs753105795, rs1553607671, rs1289665675, rs767518932, rs144567652, rs1315905872, rs1555536390, rs1166286386, rs760126773, rs755922289, rs1555591851, rs1555597094, rs915983602, rs765551897, rs768006618, rs1555594617, rs1410356625, rs1554830249, rs1268491295, rs1368374192, rs1364238660, rs1554827166, rs1554829561, rs1554830220, rs1554830789, rs1554827136, rs200719554, rs1554829555, rs1554829575, rs777918411, rs1554827159, rs1554858249, rs745882980, rs776969626, rs1555533693, rs940187828, rs753700179, rs771775516, rs986710868, rs1555534521, rs1555535472, rs34885858, rs751266148, rs1555536361, rs1555545421, rs1302083447, rs1381684916, rs1439817346, rs1555545517, rs1555540076, rs1555542860, rs775388912, rs1555547955, rs1555549451, rs1555552006, rs927630499, rs757504102, rs1555552506, rs1285346388, rs947311062, rs1247378731, rs1205909298, rs937874201, rs1555548512, rs1555564451, rs754104046, rs762526878, rs1555571116, rs1555548632, rs1485075318, rs147945881, rs753980264, rs758528624, rs1555561294, rs1365019056, rs183350210, rs751076878, rs774026652, rs761341952, rs1555581729, rs1348367722, rs1184639006, rs1477653630, rs1555574913, rs891323617, rs769479800, rs1555532944, rs1555535527, rs1555537347, rs1555538571, rs1278836130, rs745568821, rs1283284704, rs1458001028, rs1555545592, rs763378933, rs779375100, rs1555554788, rs976556567, rs753728435, rs1388128874, rs746518509, rs1232171121, rs772858764, rs1483028018, rs1484087361, rs1555532943, rs1555532946, rs1555534060, rs753063086, rs1555540048, rs372254398, rs1555545553, rs1173704265, rs1555547935, rs1448463647, rs1555549535, rs755104393, rs1555556175, rs1438828232, rs148473140, rs769580546, rs1555564436, rs1291524243, rs1555573118, rs1555575253, rs765277254, rs1555580427, rs1566260827, rs1569083679, rs1558737575, rs761039364, rs144729980, rs943009372, rs775076977, rs1205006300, rs1558727300, rs761291501, rs1563986439, rs1209807088, rs1566790465, rs1555364837, rs1567170994, rs752457319, rs1567601557, rs1567616135, rs779834525, rs1564641485, rs1564720605, rs1567782936, rs1567789009, rs1567166544, rs1374769712, rs1567786509, rs1567782755, rs1567179036, rs1567785872, rs1035139114, rs1564719070, rs1567799943, rs1567817415, rs1567593047, rs1564719151, rs773363446, rs1270367757, rs1156577591, rs903442271, rs200628199, rs1564678441, rs1567165630, rs1390620949, rs757418016, rs1567618264, rs1559399574, rs1567618907, rs769862233, rs757662453, rs1566232471, rs1567621042, rs1313006784, rs1060502588, rs1567799818, rs748000458, rs140404896, rs1291935778, rs200715208, rs1405317971, rs1567628967, rs1564720637, rs1566766719, rs140180549, rs374328858, rs753485145, rs758423821, rs1588029220, rs1588218493, rs1593903422, rs765686151, rs778744393, rs1594810556, rs1596318782, rs1596336945, rs1266198754, rs1598048941, rs1598067532, rs1186669727, rs761725308, rs1598127082, rs1598129626, rs752864343, rs1353992080, rs1598184500, rs1598191053, rs1452688134, rs1598448896, rs1598460178, rs1598460983, rs1588134748, rs754297345, rs1598120768, rs1598190568, rs1230207719, rs766989857, rs766875860, rs201811817, rs759590778, rs1601976527, rs1601976655, rs1601977379, rs1601977844, rs1601977912, rs143585647, rs1161918267, rs1602005062, rs1602005335, rs1602005463, rs1602006627, rs1602006737, rs1598116164, rs1581696699, rs1596324325, rs1596515638, rs1596519854, rs1596519879, rs1596520443, rs149851163, rs1183559927, rs1336033143, rs1598504016, rs1468320596, rs1479457172, rs753272712, rs1553433429, rs1573518300, rs1575723664, rs1575824608, rs1588101086, rs374176091, rs1588220728, rs1588220764, rs1588350264, rs1594810654, rs1588134571, rs1064793405, rs1588353886, rs1598449660, rs1598455598, rs1555593553, rs1598460710, rs45459799, rs1014112491, rs876660203, rs180177134, rs756487177, rs760150539, rs867467817, rs1825775052, rs1564667865, rs1825714345, rs1825725461, rs1831171802, rs1831172189, rs1858636931, rs1885850135, rs552052505, rs1887822022, rs773014744, rs374626826, rs1383262366, rs1888605629, rs1888681090, rs1888718087, rs757391108, rs1566782962, rs1379375089, rs2053066105, rs2053682638, rs1174332682, rs2040556390, rs2040788600, rs1281446470, rs748453841, rs2062172394, rs1035003476, rs766643461, rs779480428, rs2039078843, rs2039156731, rs1432415523, rs2040073991, rs2040090741, rs755018069, rs2040599267, rs2040853528, rs1411237340, rs2041026878, rs941660593, rs2041101553, rs2047807048, rs1567785888, rs2047958236, rs2048272509, rs2048274544, rs1829091761, rs1407605188, rs1491369358, rs1567642367, rs1175257797, rs1220672299, rs2038478071, rs2040523640, rs1885847871, rs2039603867, rs1685514075	9389754
Gastric cancer	Hereditary Diffuse Gastric Cancer	rs137854571, rs63751108, rs34612342, rs121908383, rs121909144, rs121909775, rs121909219, rs121909223, rs63750871, rs80359530, rs121964873, rs121913530, rs606231203, rs121918505, rs587776802, rs28933369, rs121912469, rs80358011, rs397507262, rs80359439, rs397507333, rs80359543, rs80358831, rs80359596, rs80358920, rs80358972, rs80359659, rs397507404, rs397514661, rs80359516, rs200495564, rs80358419, rs80359274, rs80359283, rs80358427, rs80358428, rs80358435, rs81002805, rs397507660, rs397507663, rs80359391, rs80359443, rs81002797, rs80359466, rs397507752, rs80359484, rs80359603, rs397507954, rs80359058, rs80359071, rs397507981, rs80359121, rs80357086, rs80357064, rs397508936, rs80357695, rs80357661, rs397509035, rs80357544, rs80357577, rs80357881, rs80357296, rs80356923, rs80356866, rs80357504, rs80357390, rs80357239, rs80358099, rs397509284, rs80357258, rs199474738, rs199474747, rs587779204, rs63750439, rs267608076, rs587779246, rs63749999, rs267608078, rs63751327, rs267607719, rs267607734, rs63750706, rs63751711, rs587779047, rs587779075, rs267607949, rs63750633, rs63750803, rs63751618, rs267608154, rs200640585, rs80358018, rs80357857, rs80357882, rs180177103, rs587779815, rs587779865, rs587779872, rs587780059, rs121912666, rs587780088, rs587780104, rs200432447, rs180177100, rs587780226, rs587780784, rs587776416, rs587781276, rs587781629, rs587781694, rs587781727, rs587781730, rs587781807, rs587781894, rs587781948, rs121913344, rs587782292, rs587782350, rs587782558, rs587782719, rs587782885, rs587783057, rs730881833, rs730881411, rs730881336, rs139770721, rs730881869, rs730881633, rs730882007, rs786203115, rs765123255, rs1553333738, rs762083530, rs786202800, rs17174393, rs55996097, rs750621215, rs786203451, rs747604569, rs764389018, rs786204433, rs786204862, rs772821016, rs779582317, rs863225406, rs193922343, rs759965045, rs63749919, rs760228510, rs746481984, rs762307622, rs876659736, rs876660933, rs747727055, rs1450394308, rs876658348, rs876658431, rs876659326, rs876660444, rs730881369, rs878853865, rs753862052, rs587780024, rs138941496, rs886040739, rs886040744, rs886040347, rs878854957, rs886040123, rs398122662, rs886040942, rs1057517104, rs1057516320, rs1057516683, rs879254046, rs1057517253, rs587781927, rs985033810, rs1057519989, rs775464903, rs374230313, rs758304323, rs1060501599, rs758081262, rs1060500126, rs1060502734, rs587776408, rs1060501695, rs1114167816, rs1114167596, rs1114167667, rs1555460315, rs1135402788, rs1554086196, rs730881919, rs773356478, rs769237459, rs1553653158, rs587782087, rs1555107263, rs1555119940, rs1403784434, rs1342519012, rs751710099, rs1553616361, rs1553619721, rs1270783041, rs775036118, rs1555288557, rs1555460548, rs1555461154, rs1298667185, rs1553622218, rs63751101, rs1349928568, rs771936821, rs1021662947, rs1555921011, rs81002831, rs1555124506, rs1555574803, rs1060502716, rs1555605362, rs747057367, rs1565385010, rs1567554500, rs1567516230, rs1558644995, rs1555591308, rs778306619, rs1566231194, rs1603328466, rs1570406302, rs1586108714, rs768362387, rs1597713777, rs1060502926, rs1597867185, rs1591517571, rs1591663236, rs1593903006, rs1555284779, rs1597096243, rs45459799, rs1597360340, rs587781905, rs864622481, rs1601753141, rs1966858562, rs1966967065, rs1967016153, rs1967113484, rs2080473458, rs1591387978, rs1224428422, rs1597747184, rs2082309297, rs2051929740, rs147542208	16367923
Leukemia	Leukemia, Myelocytic, Acute, Acute Myeloid Leukemia (AML-M2)	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601	17330099

Unknown
Disease name	Disease term	dbSNP ID	References
Myeloid leukemia	Acute Myeloid Leukemia, M1		17330099
Myocardial ischemia	Myocardial Ischemia		16214533
Stomach neoplasms	Malignant neoplasm of stomach, Stomach Neoplasms		16367923