MTAP (methylthioadenosine phosphorylase)

Gene

• Entrez ID: 4507
• Gene name: Methylthioadenosine phosphorylase
• Gene symbol: MTAP
• Synonyms: BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus
• Chromosome: 9
• Chromosome location: 9p21.3
• Summary: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT000961	hsa-miR-21-5p	Western blot, Northern blot	19013014
MIRT000961	hsa-miR-21-5p	qRT-PCR	19013014
MIRT000961	hsa-miR-21-5p	Luciferase reporter assay	19013014
MIRT020610	hsa-miR-155-5p	Proteomics	18668040
MIRT025319	hsa-miR-34a-5p	Sequencing	20371350
MIRT025319	hsa-miR-34a-5p	Proteomics	21566225
MIRT025319	hsa-miR-34a-5p	Proteomics	21566225
MIRT000961	hsa-miR-21-5p	Microarray	18591254
MIRT000961	hsa-miR-21-5p	Microarray	18591254
MIRT662554	hsa-miR-4714-5p	HITS-CLIP	23824327
MIRT662553	hsa-miR-514a-5p	HITS-CLIP	23824327
MIRT662552	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT662551	hsa-miR-5693	HITS-CLIP	23824327
MIRT662550	hsa-miR-1267	HITS-CLIP	23824327
MIRT662549	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT662548	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT662547	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT662546	hsa-miR-3135b	HITS-CLIP	23824327
MIRT662545	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT662544	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT662543	hsa-miR-3652	HITS-CLIP	23824327
MIRT662541	hsa-miR-4430	HITS-CLIP	23824327
MIRT662542	hsa-miR-200c-5p	HITS-CLIP	23824327
MIRT662540	hsa-miR-550a-3p	HITS-CLIP	23824327
MIRT662539	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT662538	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT662537	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT662536	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT662535	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT662534	hsa-miR-5698	HITS-CLIP	23824327
MIRT527968	hsa-miR-495-3p	PAR-CLIP	22012620
MIRT527967	hsa-miR-5688	PAR-CLIP	22012620
MIRT527966	hsa-miR-4717-3p	PAR-CLIP	22012620
MIRT527965	hsa-miR-1237-3p	PAR-CLIP	22012620
MIRT527964	hsa-miR-1248	PAR-CLIP	22012620
MIRT527963	hsa-miR-412-3p	PAR-CLIP	22012620
MIRT527962	hsa-miR-6754-3p	PAR-CLIP	22012620
MIRT527961	hsa-miR-6837-3p	PAR-CLIP	22012620
MIRT527960	hsa-miR-4778-3p	PAR-CLIP	22012620
MIRT527959	hsa-miR-130a-5p	PAR-CLIP	22012620
MIRT527958	hsa-miR-23a-3p	PAR-CLIP	22012620
MIRT527957	hsa-miR-23b-3p	PAR-CLIP	22012620
MIRT527956	hsa-miR-23c	PAR-CLIP	22012620
MIRT527955	hsa-miR-6868-3p	PAR-CLIP	22012620
MIRT454726	hsa-miR-4662a-3p	PAR-CLIP	23592263
MIRT454725	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT454724	hsa-miR-577	PAR-CLIP	23592263
MIRT454723	hsa-miR-4709-5p	PAR-CLIP	23592263
MIRT454722	hsa-miR-125a-3p	PAR-CLIP	23592263
MIRT454721	hsa-miR-421	PAR-CLIP	23592263
MIRT454720	hsa-miR-5585-3p	PAR-CLIP	23592263
MIRT662554	hsa-miR-4714-5p	HITS-CLIP	23824327
MIRT662553	hsa-miR-514a-5p	HITS-CLIP	23824327
MIRT662552	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT662551	hsa-miR-5693	HITS-CLIP	23824327
MIRT662550	hsa-miR-1267	HITS-CLIP	23824327
MIRT662549	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT662548	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT662547	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT662546	hsa-miR-3135b	HITS-CLIP	23824327
MIRT662545	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT662544	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT662543	hsa-miR-3652	HITS-CLIP	23824327
MIRT662541	hsa-miR-4430	HITS-CLIP	23824327
MIRT662542	hsa-miR-200c-5p	HITS-CLIP	23824327
MIRT662540	hsa-miR-550a-3p	HITS-CLIP	23824327
MIRT662539	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT662538	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT662537	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT662536	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT662535	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT662534	hsa-miR-5698	HITS-CLIP	23824327
MIRT527968	hsa-miR-495-3p	PAR-CLIP	22012620
MIRT527967	hsa-miR-5688	PAR-CLIP	22012620
MIRT527966	hsa-miR-4717-3p	PAR-CLIP	22012620
MIRT527965	hsa-miR-1237-3p	PAR-CLIP	22012620
MIRT527964	hsa-miR-1248	PAR-CLIP	22012620
MIRT527963	hsa-miR-412-3p	PAR-CLIP	22012620
MIRT527962	hsa-miR-6754-3p	PAR-CLIP	22012620
MIRT527961	hsa-miR-6837-3p	PAR-CLIP	22012620
MIRT527960	hsa-miR-4778-3p	PAR-CLIP	22012620
MIRT527959	hsa-miR-130a-5p	PAR-CLIP	22012620
MIRT527958	hsa-miR-23a-3p	PAR-CLIP	22012620
MIRT527957	hsa-miR-23b-3p	PAR-CLIP	22012620
MIRT527956	hsa-miR-23c	PAR-CLIP	22012620
MIRT527955	hsa-miR-6868-3p	PAR-CLIP	22012620
MIRT454726	hsa-miR-4662a-3p	PAR-CLIP	23592263
MIRT454725	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT454724	hsa-miR-577	PAR-CLIP	23592263
MIRT454723	hsa-miR-4709-5p	PAR-CLIP	23592263
MIRT454722	hsa-miR-125a-3p	PAR-CLIP	23592263
MIRT454721	hsa-miR-421	PAR-CLIP	23592263
MIRT454720	hsa-miR-5585-3p	PAR-CLIP	23592263
MIRT1162199	hsa-miR-1193	CLIP-seq
MIRT1162200	hsa-miR-1204	CLIP-seq
MIRT1162201	hsa-miR-1253	CLIP-seq
MIRT1162202	hsa-miR-1262	CLIP-seq
MIRT1162203	hsa-miR-1279	CLIP-seq
MIRT1162204	hsa-miR-128	CLIP-seq
MIRT1162205	hsa-miR-1290	CLIP-seq
MIRT1162206	hsa-miR-1293	CLIP-seq
MIRT1162207	hsa-miR-1299	CLIP-seq
MIRT1162208	hsa-miR-142-3p	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT1162210	hsa-miR-1470	CLIP-seq
MIRT1162211	hsa-miR-154	CLIP-seq
MIRT1162212	hsa-miR-15a	CLIP-seq
MIRT1162213	hsa-miR-15b	CLIP-seq
MIRT1162214	hsa-miR-16	CLIP-seq
MIRT1162215	hsa-miR-188-3p	CLIP-seq
MIRT1162216	hsa-miR-195	CLIP-seq
MIRT1162217	hsa-miR-1972	CLIP-seq
MIRT1162218	hsa-miR-1976	CLIP-seq
MIRT1162219	hsa-miR-2392	CLIP-seq
MIRT1162220	hsa-miR-2467-5p	CLIP-seq
MIRT1162221	hsa-miR-27a	CLIP-seq
MIRT1162222	hsa-miR-27b	CLIP-seq
MIRT1162223	hsa-miR-298	CLIP-seq
MIRT1162224	hsa-miR-3123	CLIP-seq
MIRT1162225	hsa-miR-3144-5p	CLIP-seq
MIRT1162226	hsa-miR-3154	CLIP-seq
MIRT1162227	hsa-miR-3156-3p	CLIP-seq
MIRT1162228	hsa-miR-3163	CLIP-seq
MIRT1162229	hsa-miR-3175	CLIP-seq
MIRT1162230	hsa-miR-3179	CLIP-seq
MIRT1162231	hsa-miR-3182	CLIP-seq
MIRT1162232	hsa-miR-3191	CLIP-seq
MIRT1162233	hsa-miR-3199	CLIP-seq
MIRT1162234	hsa-miR-338-5p	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT1162236	hsa-miR-3606	CLIP-seq
MIRT1162237	hsa-miR-361-3p	CLIP-seq
MIRT1162238	hsa-miR-3647-3p	CLIP-seq
MIRT1162239	hsa-miR-3653	CLIP-seq
MIRT1162240	hsa-miR-3655	CLIP-seq
MIRT1162241	hsa-miR-3658	CLIP-seq
MIRT1162242	hsa-miR-378	CLIP-seq
MIRT1162243	hsa-miR-378b	CLIP-seq
MIRT1162244	hsa-miR-378c	CLIP-seq
MIRT1162245	hsa-miR-378d	CLIP-seq
MIRT1162246	hsa-miR-378e	CLIP-seq
MIRT1162247	hsa-miR-378f	CLIP-seq
MIRT1162248	hsa-miR-378h	CLIP-seq
MIRT1162249	hsa-miR-378i	CLIP-seq
MIRT1162250	hsa-miR-3912	CLIP-seq
MIRT1162251	hsa-miR-3915	CLIP-seq
MIRT1162252	hsa-miR-3919	CLIP-seq
MIRT1162253	hsa-miR-3925-5p	CLIP-seq
MIRT1162254	hsa-miR-3928	CLIP-seq
MIRT1162255	hsa-miR-422a	CLIP-seq
MIRT1162256	hsa-miR-424	CLIP-seq
MIRT1162257	hsa-miR-4261	CLIP-seq
MIRT1162258	hsa-miR-4272	CLIP-seq
MIRT1162259	hsa-miR-4278	CLIP-seq
MIRT1162260	hsa-miR-4282	CLIP-seq
MIRT1162261	hsa-miR-4301	CLIP-seq
MIRT1162262	hsa-miR-431	CLIP-seq
MIRT1162263	hsa-miR-4434	CLIP-seq
MIRT1162264	hsa-miR-4436b-5p	CLIP-seq
MIRT1162265	hsa-miR-4477a	CLIP-seq
MIRT1162266	hsa-miR-4483	CLIP-seq
MIRT1162267	hsa-miR-4516	CLIP-seq
MIRT1162268	hsa-miR-4524	CLIP-seq
MIRT1162269	hsa-miR-4638-3p	CLIP-seq
MIRT1162270	hsa-miR-4650-5p	CLIP-seq
MIRT1162271	hsa-miR-4652-5p	CLIP-seq
MIRT1162272	hsa-miR-4659a-3p	CLIP-seq
MIRT1162273	hsa-miR-4659b-3p	CLIP-seq
MIRT1162274	hsa-miR-4662a-5p	CLIP-seq
MIRT1162275	hsa-miR-4666-3p	CLIP-seq
MIRT1162276	hsa-miR-4667-3p	CLIP-seq
MIRT1162277	hsa-miR-4676-5p	CLIP-seq
MIRT1162278	hsa-miR-4701-3p	CLIP-seq
MIRT1162279	hsa-miR-4705	CLIP-seq
MIRT1162280	hsa-miR-4716-3p	CLIP-seq
MIRT1162281	hsa-miR-4717-5p	CLIP-seq
MIRT1162282	hsa-miR-4723-5p	CLIP-seq
MIRT1162283	hsa-miR-4764-3p	CLIP-seq
MIRT1162284	hsa-miR-4777-3p	CLIP-seq
MIRT1162285	hsa-miR-4782-5p	CLIP-seq
MIRT1162286	hsa-miR-4790-3p	CLIP-seq
MIRT1162287	hsa-miR-4793-5p	CLIP-seq
MIRT1162288	hsa-miR-491-5p	CLIP-seq
MIRT1162289	hsa-miR-495	CLIP-seq
MIRT1162290	hsa-miR-497	CLIP-seq
MIRT1162291	hsa-miR-503	CLIP-seq
MIRT1162292	hsa-miR-511	CLIP-seq
MIRT1162293	hsa-miR-516b	CLIP-seq
MIRT1162294	hsa-miR-532-3p	CLIP-seq
MIRT1162295	hsa-miR-548a-5p	CLIP-seq
MIRT1162296	hsa-miR-548ab	CLIP-seq
MIRT1162297	hsa-miR-548ac	CLIP-seq
MIRT1162298	hsa-miR-548ae	CLIP-seq
MIRT1162299	hsa-miR-548aj	CLIP-seq
MIRT1162300	hsa-miR-548ak	CLIP-seq
MIRT1162301	hsa-miR-548am	CLIP-seq
MIRT1162302	hsa-miR-548b-5p	CLIP-seq
MIRT1162303	hsa-miR-548c-5p	CLIP-seq
MIRT1162304	hsa-miR-548d-3p	CLIP-seq
MIRT1162305	hsa-miR-548d-5p	CLIP-seq
MIRT1162306	hsa-miR-548h	CLIP-seq
MIRT1162307	hsa-miR-548i	CLIP-seq
MIRT1162308	hsa-miR-548j	CLIP-seq
MIRT1162309	hsa-miR-548n	CLIP-seq
MIRT1162310	hsa-miR-548p	CLIP-seq
MIRT1162311	hsa-miR-548w	CLIP-seq
MIRT1162312	hsa-miR-548x	CLIP-seq
MIRT1162313	hsa-miR-548y	CLIP-seq
MIRT1162314	hsa-miR-548z	CLIP-seq
MIRT1162315	hsa-miR-552	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT1162317	hsa-miR-559	CLIP-seq
MIRT1162318	hsa-miR-570	CLIP-seq
MIRT1162319	hsa-miR-575	CLIP-seq
MIRT1162320	hsa-miR-583	CLIP-seq
MIRT1162321	hsa-miR-600	CLIP-seq
MIRT1162322	hsa-miR-624	CLIP-seq
MIRT1162323	hsa-miR-633	CLIP-seq
MIRT1162324	hsa-miR-640	CLIP-seq
MIRT1162325	hsa-miR-646	CLIP-seq
MIRT1162326	hsa-miR-661	CLIP-seq
MIRT1162327	hsa-miR-664	CLIP-seq
MIRT1162328	hsa-miR-665	CLIP-seq
MIRT1162329	hsa-miR-764	CLIP-seq
MIRT1556704	hsa-miR-3662	CLIP-seq
MIRT2046502	hsa-miR-1178	CLIP-seq
MIRT2046503	hsa-miR-122	CLIP-seq
MIRT2046504	hsa-miR-1228	CLIP-seq
MIRT2046505	hsa-miR-1270	CLIP-seq
MIRT2046506	hsa-miR-1292	CLIP-seq
MIRT2046507	hsa-miR-129-5p	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT2046508	hsa-miR-146a	CLIP-seq
MIRT2046509	hsa-miR-146b-5p	CLIP-seq
MIRT2046510	hsa-miR-185	CLIP-seq
MIRT2046511	hsa-miR-1915	CLIP-seq
MIRT1162218	hsa-miR-1976	CLIP-seq
MIRT2046512	hsa-miR-2276	CLIP-seq
MIRT2046513	hsa-miR-299-3p	CLIP-seq
MIRT2046514	hsa-miR-3115	CLIP-seq
MIRT2046515	hsa-miR-3149	CLIP-seq
MIRT2046516	hsa-miR-3151	CLIP-seq
MIRT2046517	hsa-miR-3194-3p	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT2046518	hsa-miR-3690	CLIP-seq
MIRT2046519	hsa-miR-377	CLIP-seq
MIRT2046520	hsa-miR-3921	CLIP-seq
MIRT1162253	hsa-miR-3925-5p	CLIP-seq
MIRT2046521	hsa-miR-4254	CLIP-seq
MIRT1162258	hsa-miR-4272	CLIP-seq
MIRT2046522	hsa-miR-4284	CLIP-seq
MIRT2046523	hsa-miR-4306	CLIP-seq
MIRT2046524	hsa-miR-4447	CLIP-seq
MIRT2046525	hsa-miR-4450	CLIP-seq
MIRT2046526	hsa-miR-4471	CLIP-seq
MIRT2046527	hsa-miR-4472	CLIP-seq
MIRT2046528	hsa-miR-4531	CLIP-seq
MIRT2046529	hsa-miR-4644	CLIP-seq
MIRT2046530	hsa-miR-4653-5p	CLIP-seq
MIRT1162272	hsa-miR-4659a-3p	CLIP-seq
MIRT1162273	hsa-miR-4659b-3p	CLIP-seq
MIRT2046531	hsa-miR-4699-3p	CLIP-seq
MIRT2046532	hsa-miR-4726-3p	CLIP-seq
MIRT2046533	hsa-miR-4735-5p	CLIP-seq
MIRT2046534	hsa-miR-4772-3p	CLIP-seq
MIRT2046535	hsa-miR-4775	CLIP-seq
MIRT1162284	hsa-miR-4777-3p	CLIP-seq
MIRT1162287	hsa-miR-4793-5p	CLIP-seq
MIRT1162288	hsa-miR-491-5p	CLIP-seq
MIRT2046536	hsa-miR-513b	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT1162320	hsa-miR-583	CLIP-seq
MIRT2046537	hsa-miR-590-3p	CLIP-seq
MIRT2046538	hsa-miR-620	CLIP-seq
MIRT2046539	hsa-miR-767-3p	CLIP-seq
MIRT2046502	hsa-miR-1178	CLIP-seq
MIRT2275614	hsa-miR-1200	CLIP-seq
MIRT2275615	hsa-miR-1208	CLIP-seq
MIRT2046503	hsa-miR-122	CLIP-seq
MIRT2046504	hsa-miR-1228	CLIP-seq
MIRT2275616	hsa-miR-1243	CLIP-seq
MIRT1162202	hsa-miR-1262	CLIP-seq
MIRT1162203	hsa-miR-1279	CLIP-seq
MIRT1162204	hsa-miR-128	CLIP-seq
MIRT1162205	hsa-miR-1290	CLIP-seq
MIRT2046506	hsa-miR-1292	CLIP-seq
MIRT1162206	hsa-miR-1293	CLIP-seq
MIRT2275617	hsa-miR-1305	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT2275618	hsa-miR-146b-3p	CLIP-seq
MIRT1162210	hsa-miR-1470	CLIP-seq
MIRT1162212	hsa-miR-15a	CLIP-seq
MIRT1162213	hsa-miR-15b	CLIP-seq
MIRT1162214	hsa-miR-16	CLIP-seq
MIRT1162215	hsa-miR-188-3p	CLIP-seq
MIRT2046511	hsa-miR-1915	CLIP-seq
MIRT1162216	hsa-miR-195	CLIP-seq
MIRT1162218	hsa-miR-1976	CLIP-seq
MIRT2275619	hsa-miR-200b	CLIP-seq
MIRT2275620	hsa-miR-200c	CLIP-seq
MIRT2275621	hsa-miR-2052	CLIP-seq
MIRT2275622	hsa-miR-216a	CLIP-seq
MIRT2046512	hsa-miR-2276	CLIP-seq
MIRT1162221	hsa-miR-27a	CLIP-seq
MIRT1162222	hsa-miR-27b	CLIP-seq
MIRT2046513	hsa-miR-299-3p	CLIP-seq
MIRT2275623	hsa-miR-302f	CLIP-seq
MIRT2046514	hsa-miR-3115	CLIP-seq
MIRT1162224	hsa-miR-3123	CLIP-seq
MIRT2275624	hsa-miR-3126-5p	CLIP-seq
MIRT1162225	hsa-miR-3144-5p	CLIP-seq
MIRT2046516	hsa-miR-3151	CLIP-seq
MIRT1162227	hsa-miR-3156-3p	CLIP-seq
MIRT2275625	hsa-miR-3157-3p	CLIP-seq
MIRT2275626	hsa-miR-3173-3p	CLIP-seq
MIRT2275627	hsa-miR-3173-5p	CLIP-seq
MIRT1162232	hsa-miR-3191	CLIP-seq
MIRT1162233	hsa-miR-3199	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT2275628	hsa-miR-342-3p	CLIP-seq
MIRT2275629	hsa-miR-3616-5p	CLIP-seq
MIRT2275630	hsa-miR-3647-5p	CLIP-seq
MIRT2275631	hsa-miR-3654	CLIP-seq
MIRT2275632	hsa-miR-3668	CLIP-seq
MIRT2275633	hsa-miR-3686	CLIP-seq
MIRT2275634	hsa-miR-3692	CLIP-seq
MIRT2275635	hsa-miR-374c	CLIP-seq
MIRT2046519	hsa-miR-377	CLIP-seq
MIRT2275636	hsa-miR-3909	CLIP-seq
MIRT1162252	hsa-miR-3919	CLIP-seq
MIRT1162253	hsa-miR-3925-5p	CLIP-seq
MIRT2275637	hsa-miR-3973	CLIP-seq
MIRT1162256	hsa-miR-424	CLIP-seq
MIRT1162258	hsa-miR-4272	CLIP-seq
MIRT2275638	hsa-miR-4279	CLIP-seq
MIRT2275639	hsa-miR-429	CLIP-seq
MIRT1162261	hsa-miR-4301	CLIP-seq
MIRT1162262	hsa-miR-431	CLIP-seq
MIRT2275640	hsa-miR-4324	CLIP-seq
MIRT2275641	hsa-miR-4330	CLIP-seq
MIRT2275642	hsa-miR-4420	CLIP-seq
MIRT2046524	hsa-miR-4447	CLIP-seq
MIRT2046525	hsa-miR-4450	CLIP-seq
MIRT2046526	hsa-miR-4471	CLIP-seq
MIRT2046527	hsa-miR-4472	CLIP-seq
MIRT1162266	hsa-miR-4483	CLIP-seq
MIRT2275643	hsa-miR-452	CLIP-seq
MIRT2275644	hsa-miR-4522	CLIP-seq
MIRT1162268	hsa-miR-4524	CLIP-seq
MIRT2275645	hsa-miR-4540	CLIP-seq
MIRT2275646	hsa-miR-4635	CLIP-seq
MIRT1162271	hsa-miR-4652-5p	CLIP-seq
MIRT1162276	hsa-miR-4667-3p	CLIP-seq
MIRT2275647	hsa-miR-4676-3p	CLIP-seq
MIRT2275648	hsa-miR-4691-5p	CLIP-seq
MIRT2275649	hsa-miR-4698	CLIP-seq
MIRT1162278	hsa-miR-4701-3p	CLIP-seq
MIRT2275650	hsa-miR-4715-5p	CLIP-seq
MIRT2275651	hsa-miR-4722-3p	CLIP-seq
MIRT2046532	hsa-miR-4726-3p	CLIP-seq
MIRT2275652	hsa-miR-4732-5p	CLIP-seq
MIRT2275653	hsa-miR-4742-3p	CLIP-seq
MIRT2275654	hsa-miR-4756-3p	CLIP-seq
MIRT1162283	hsa-miR-4764-3p	CLIP-seq
MIRT1162284	hsa-miR-4777-3p	CLIP-seq
MIRT2275655	hsa-miR-4779	CLIP-seq
MIRT2275656	hsa-miR-487a	CLIP-seq
MIRT1162288	hsa-miR-491-5p	CLIP-seq
MIRT1162290	hsa-miR-497	CLIP-seq
MIRT2275657	hsa-miR-498	CLIP-seq
MIRT2275658	hsa-miR-499-3p	CLIP-seq
MIRT2275659	hsa-miR-499a-3p	CLIP-seq
MIRT2275660	hsa-miR-501-5p	CLIP-seq
MIRT1162291	hsa-miR-503	CLIP-seq
MIRT2046536	hsa-miR-513b	CLIP-seq
MIRT1162294	hsa-miR-532-3p	CLIP-seq
MIRT2275661	hsa-miR-539	CLIP-seq
MIRT2275662	hsa-miR-544b	CLIP-seq
MIRT2275663	hsa-miR-548k	CLIP-seq
MIRT2275664	hsa-miR-550b	CLIP-seq
MIRT1162315	hsa-miR-552	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT2275665	hsa-miR-573	CLIP-seq
MIRT2275666	hsa-miR-576-3p	CLIP-seq
MIRT1162320	hsa-miR-583	CLIP-seq
MIRT1162325	hsa-miR-646	CLIP-seq
MIRT2275667	hsa-miR-647	CLIP-seq
MIRT2275668	hsa-miR-655	CLIP-seq
MIRT2275669	hsa-miR-873	CLIP-seq
MIRT2275670	hsa-miR-874	CLIP-seq
MIRT1162199	hsa-miR-1193	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT1162218	hsa-miR-1976	CLIP-seq
MIRT1162219	hsa-miR-2392	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT1162324	hsa-miR-640	CLIP-seq
MIRT2275632	hsa-miR-3668	CLIP-seq
MIRT2275637	hsa-miR-3973	CLIP-seq
MIRT2275652	hsa-miR-4732-5p	CLIP-seq
MIRT2275663	hsa-miR-548k	CLIP-seq
MIRT1162205	hsa-miR-1290	CLIP-seq
MIRT2046507	hsa-miR-129-5p	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT2454533	hsa-miR-203	CLIP-seq
MIRT2046515	hsa-miR-3149	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT2454534	hsa-miR-411	CLIP-seq
MIRT2046533	hsa-miR-4735-5p	CLIP-seq
MIRT2046535	hsa-miR-4775	CLIP-seq
MIRT1162288	hsa-miR-491-5p	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT1162320	hsa-miR-583	CLIP-seq
MIRT2046537	hsa-miR-590-3p	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT1162320	hsa-miR-583	CLIP-seq
MIRT2046506	hsa-miR-1292	CLIP-seq
MIRT2046507	hsa-miR-129-5p	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT2046513	hsa-miR-299-3p	CLIP-seq
MIRT2046514	hsa-miR-3115	CLIP-seq
MIRT2046515	hsa-miR-3149	CLIP-seq
MIRT2046516	hsa-miR-3151	CLIP-seq
MIRT1162233	hsa-miR-3199	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT2454534	hsa-miR-411	CLIP-seq
MIRT2046524	hsa-miR-4447	CLIP-seq
MIRT2046525	hsa-miR-4450	CLIP-seq
MIRT2046526	hsa-miR-4471	CLIP-seq
MIRT2046527	hsa-miR-4472	CLIP-seq
MIRT1162272	hsa-miR-4659a-3p	CLIP-seq
MIRT1162273	hsa-miR-4659b-3p	CLIP-seq
MIRT2046533	hsa-miR-4735-5p	CLIP-seq
MIRT2046535	hsa-miR-4775	CLIP-seq
MIRT1162288	hsa-miR-491-5p	CLIP-seq
MIRT1162315	hsa-miR-552	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT1162320	hsa-miR-583	CLIP-seq
MIRT2046537	hsa-miR-590-3p	CLIP-seq
MIRT1162329	hsa-miR-764	CLIP-seq
MIRT2046506	hsa-miR-1292	CLIP-seq
MIRT2046507	hsa-miR-129-5p	CLIP-seq
MIRT1162209	hsa-miR-142-5p	CLIP-seq
MIRT2046513	hsa-miR-299-3p	CLIP-seq
MIRT2046514	hsa-miR-3115	CLIP-seq
MIRT2046515	hsa-miR-3149	CLIP-seq
MIRT2046516	hsa-miR-3151	CLIP-seq
MIRT1162233	hsa-miR-3199	CLIP-seq
MIRT1162235	hsa-miR-340	CLIP-seq
MIRT2454534	hsa-miR-411	CLIP-seq
MIRT2046524	hsa-miR-4447	CLIP-seq
MIRT2046525	hsa-miR-4450	CLIP-seq
MIRT2046526	hsa-miR-4471	CLIP-seq
MIRT2046527	hsa-miR-4472	CLIP-seq
MIRT2046533	hsa-miR-4735-5p	CLIP-seq
MIRT2046535	hsa-miR-4775	CLIP-seq
MIRT1162288	hsa-miR-491-5p	CLIP-seq
MIRT1162315	hsa-miR-552	CLIP-seq
MIRT1162316	hsa-miR-555	CLIP-seq
MIRT1162320	hsa-miR-583	CLIP-seq
MIRT2046537	hsa-miR-590-3p	CLIP-seq
MIRT1162329	hsa-miR-764	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004645	Function	1,4-alpha-oligoglucan phosphorylase activity	TAS	8687427
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006139	Process	Nucleobase-containing compound metabolic process	TAS	8687427
GO:0006166	Process	Purine ribonucleoside salvage	IEA
GO:0006738	Process	Nicotinamide riboside catabolic process	IDA	19001417
GO:0017061	Function	S-methyl-5-thioadenosine phosphorylase activity	IBA	21873635
GO:0019509	Process	L-methionine salvage from methylthioadenosine	IBA	21873635
GO:0019509	Process	L-methionine salvage from methylthioadenosine	IEA
GO:0019509	Process	L-methionine salvage from methylthioadenosine	TAS
GO:0033574	Process	Response to testosterone	IEA
GO:0035722	Process	Interleukin-12-mediated signaling pathway	TAS
GO:0070062	Component	Extracellular exosome	HDA	19056867

Other IDs

• MIM: 156540
• HGNC: 7413
• e!Ensembl: ENSG00000099810

Protein

• UniProt ID: Q13126
• Protein name: S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase)
• Protein function: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the meth
• PDB: 1CB0, 1CG6, 1K27, 1SD1, 1SD2, 3LN5, 3OZC, 3OZD, 3OZE, 5EUB, 5TC5, 5TC6, 5TC7, 5TC8, 6DYZ, 6DZ0, 6DZ2, 6DZ3
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01048	PNP_UDP_1	11 → 256	Phosphorylase superfamily	Domain

• Sequence:

  MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLAR
  HGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMR
  PQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
  AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTL
  KENANKAKSLLLTTIPQIGSTEWSETLHNLKNMAQFSVLLPRH

• Sequence length: 283

Pathways

KEGG:

Cysteine and methionine metabolism
Metabolic pathways

Reactome:

Methionine salvage pathway
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Diaphyseal medullary stenosis-bone malignancy syndrome	Diaphyseal medullary stenosis-bone malignancy syndrome	rs2131048129, rs2131048008
Esophagus neoplasm	Esophageal Neoplasms	rs28934578, rs121918714, rs1567556006, rs1575166666	22960999
Lung adenocarcinoma	Adenocarcinoma of lung (disorder)	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382	28604730
Melanoma	melanoma, Cutaneous Melanoma	rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs1563902635, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050	19578364, 21706340, 21983787, 28212542, 30429480
Nasopharyngeal carcinoma	Nasopharyngeal carcinoma	rs200046052	20512145
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	21716162

Unknown
Disease name	Disease term	dbSNP ID	References
Diaphyseal medullary stenosis with bone malignancy	Diaphyseal medullary stenosis with bone malignancy
Diaphyseal medullary stenosis with malignant fibrous histiocytoma	Diaphyseal medullary stenosis with malignant fibrous histiocytoma		22464254
Fibrosarcoma	Fibrosarcoma
Histiocytoma	Histiocytoma
Malignant melanoma of skin	Malignant melanoma of skin of lower limb, Malignant melanoma of skin of upper limb	rs16891982	30429480
Nevus	Nevus		19578365
Osteopenia	Osteopenia
Osteosarcoma	Osteosarcoma
Presenile cataract	Presenile cataract
Prostatic neoplasms	Prostatic Neoplasms		21716162
Stenosis of the medullary cavity of the long bones	Stenosis of the medullary cavity of the long bones