MT1F (metallothionein 1F)

Gene

• Entrez ID: 4494
• Gene name: Metallothionein 1F
• Gene symbol: MT1F
• Synonyms: MT1
• Chromosome: 16
• Chromosome location: 16q13

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024377	hsa-miR-215-5p	Microarray	19074876
MIRT026619	hsa-miR-192-5p	Microarray	19074876
MIRT438743	hsa-miR-219a-5p	qRT-PCR	24974767
MIRT438743	hsa-miR-219a-5p	qRT-PCR	24974767
MIRT438743	hsa-miR-219a-5p	qRT-PCR	24974767
MIRT438743	hsa-miR-219a-5p	qRT-PCR	24974767
MIRT1162111	hsa-miR-1	CLIP-seq
MIRT1162112	hsa-miR-206	CLIP-seq
MIRT1162113	hsa-miR-27a	CLIP-seq
MIRT1162114	hsa-miR-27b	CLIP-seq
MIRT1162115	hsa-miR-513a-5p	CLIP-seq
MIRT1162116	hsa-miR-548p	CLIP-seq
MIRT1162117	hsa-miR-613	CLIP-seq
MIRT1162111	hsa-miR-1	CLIP-seq
MIRT1162112	hsa-miR-206	CLIP-seq
MIRT1162113	hsa-miR-27a	CLIP-seq
MIRT1162114	hsa-miR-27b	CLIP-seq
MIRT2046463	hsa-miR-4506	CLIP-seq
MIRT1162115	hsa-miR-513a-5p	CLIP-seq
MIRT1162116	hsa-miR-548p	CLIP-seq
MIRT1162117	hsa-miR-613	CLIP-seq
MIRT2275573	hsa-miR-34c-3p	CLIP-seq
MIRT2275574	hsa-miR-944	CLIP-seq
MIRT1162111	hsa-miR-1	CLIP-seq
MIRT1162112	hsa-miR-206	CLIP-seq
MIRT1162113	hsa-miR-27a	CLIP-seq
MIRT1162114	hsa-miR-27b	CLIP-seq
MIRT2046463	hsa-miR-4506	CLIP-seq
MIRT1162115	hsa-miR-513a-5p	CLIP-seq
MIRT1162116	hsa-miR-548p	CLIP-seq
MIRT1162117	hsa-miR-613	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
FOXF2	Repression	19562724

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	8619255
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	8619255
GO:0006882	Process	Cellular zinc ion homeostasis	IBA	21873635
GO:0008270	Function	Zinc ion binding	ISS
GO:0010273	Process	Detoxification of copper ion	IBA	21873635
GO:0045926	Process	Negative regulation of growth	ISS
GO:0046872	Function	Metal ion binding	IBA	21873635
GO:0071276	Process	Cellular response to cadmium ion	IBA	21873635
GO:0071276	Process	Cellular response to cadmium ion	IEP	16827180
GO:0071280	Process	Cellular response to copper ion	IBA	21873635
GO:0071294	Process	Cellular response to zinc ion	IBA	21873635
GO:0071294	Process	Cellular response to zinc ion	ISS

Other IDs

• MIM: 156352
• HGNC: 7398
• e!Ensembl: ENSG00000198417

Protein

• UniProt ID: P04733
• Protein name: Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF)
• Protein function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00131	Metallothio	1 → 61	Metallothionein	Domain

• Sequence:

  MDPNCSCAAGVSCTCAGSCKCKECKCTSCKKSCCSCCPVGCSKCAQGCVCKGASEKCSCC
  D

• Sequence length: 61

Pathways

KEGG:

Mineral absorption

Associated diseases

Unknown
Disease name	Disease term	dbSNP ID	References
Liver carcinoma	Liver carcinoma		28284560