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MIR148A (microRNA 148a)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
406940
Gene nameGene Name - the full gene name approved by the HGNC.
MicroRNA 148a
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
MIR148A
SynonymsGene synonyms aliases
MIRN148, MIRN148A, hsa-mir-148, mir-148a
ChromosomeChromosome number
7
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p15.2
SummarySummary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space HDA 26646931
GO:0010985 Process Negative regulation of lipoprotein particle clearance ISS
GO:0010989 Process Negative regulation of low-density lipoprotein particle clearance IDA 26437365
GO:0035195 Process Gene silencing by miRNA IDA 20483747, 26437365, 26501192, 30451334
GO:0035195 Process Gene silencing by miRNA IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Interactions View interactions
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Pancreatitis Pancreatitis rs61734659 27840954
Kidney failure Kidney Failure, Acute 30682439
Acute kidney insufficiency Acute Kidney Insufficiency 30682439

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