MIR144 (microRNA 144)

Gene

• Entrez ID: 406936
• Gene name: MicroRNA 144
• Gene symbol: MIR144
• Synonyms: MIRN144, mir-144
• Chromosome: 17
• Chromosome location: 17q11.2
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	27329039, 27785072
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0010561	Process	Negative regulation of glycoprotein biosynthetic process	IDA	27785072
GO:0010628	Process	Positive regulation of gene expression	IDA	27785072
GO:0010629	Process	Negative regulation of gene expression	IDA	27785072
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IDA	27785072
GO:0010822	Process	Positive regulation of mitochondrion organization	IDA	27329039
GO:0010886	Process	Positive regulation of cholesterol storage	IGI	24733347
GO:0010983	Process	Positive regulation of high-density lipoprotein particle clearance	ISS	23519695
GO:0032731	Process	Positive regulation of interleukin-1 beta production	IDA	24733347
GO:0032755	Process	Positive regulation of interleukin-6 production	IDA	24733347
GO:0032760	Process	Positive regulation of tumor necrosis factor production	IDA	24733347
GO:0035195	Process	Gene silencing by miRNA	IDA	23519695, 24733347, 27785072, 30499593, 30511586
GO:0035195	Process	Gene silencing by miRNA	IEA
GO:0035278	Process	MiRNA mediated inhibition of translation	IDA	27329039
GO:0042632	Process	Cholesterol homeostasis	IDA	23519695
GO:0042632	Process	Cholesterol homeostasis	IGI	24733347
GO:0042985	Process	Negative regulation of amyloid precursor protein biosynthetic process	IDA	27329039
GO:0043433	Process	Negative regulation of DNA-binding transcription factor activity	IDA	27785072
GO:0050729	Process	Positive regulation of inflammatory response	IDA	24733347
GO:0060355	Process	Positive regulation of cell adhesion molecule production	IDA	27785072
GO:0090107	Process	Regulation of high-density lipoprotein particle assembly	IGI	24733347
GO:0090370	Process	Negative regulation of cholesterol efflux	IDA	23519695
GO:0090370	Process	Negative regulation of cholesterol efflux	IGI	24733347
GO:1903063	Process	Negative regulation of reverse cholesterol transport	IGI	24733347
GO:1903231	Function	MRNA binding involved in posttranscriptional gene silencing	IDA	23519695, 24733347, 27329039, 27785072, 30499593, 30511586

Other IDs

• MIM: 612070
• HGNC: 31531
• e!Ensembl: ENSG00000283819

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs4402960, rs1362648752, rs3745368, rs3792267, rs3842570, rs5030952, rs2975760, rs119489103, rs7903146, rs12255372, rs11196205, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs137852740, rs137852786, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs80356663, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356666, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs387906779, rs141804752, rs182349376, rs184917682, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs61736969, rs587783673, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs797045623, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs1553638903, rs1553638909, rs948820149, rs371977235, rs1553784995, rs76474829, rs200998587, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs776793516, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	28545106
Lung adenocarcinoma	Bronchioloalveolar Adenocarcinoma	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382	25926378

Unknown
Disease name	Disease term	dbSNP ID	References
Adenoma	Adenoma, Adenoma, Basal Cell, Follicular adenoma, Adenoma, Microcystic, Adenoma, Monomorphic, Adenoma, Trabecular		25926378
Papillary adenoma	Papillary adenoma		25926378