MIR130A (microRNA 130a)

Gene

• Entrez ID: 406919
• Gene name: MicroRNA 130a
• Gene symbol: MIR130A
• Synonyms: MIRN130A, miRNA130A, mir-130a
• Chromosome: 11
• Chromosome location: 11q12.1
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	26398698, 31368668
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IDA	26435691
GO:0035195	Process	Gene silencing by miRNA	IDA	21067317, 24801815, 24960162, 25681685, 26398698, 26435691, 31368668
GO:0035195	Process	Gene silencing by miRNA	IEA
GO:0038061	Process	NIK/NF-kappaB signaling	IDA	26435691
GO:0043031	Process	Negative regulation of macrophage activation	IMP	26398698
GO:0045766	Process	Positive regulation of angiogenesis	IMP	23136161
GO:0098586	Process	Cellular response to virus	IMP	23418453
GO:1903231	Function	MRNA binding involved in posttranscriptional gene silencing	IDA	21067317, 24801815, 24960162, 25681685, 26398698, 26435691, 31368668
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903900	Process	Regulation of viral life cycle	IMP	23418453
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	IDA	24960162, 25681685
GO:1905564	Process	Positive regulation of vascular endothelial cell proliferation	IDA	24960162

Other IDs

• MIM: 610175
• HGNC: 31514
• e!Ensembl: ENSG00000208009

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Lung adenocarcinoma	Bronchioloalveolar Adenocarcinoma	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382	25926378
Obesity	Obesity	rs34911341, rs74315349, rs1474810899, rs2282440, rs2491132, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs74315393, rs121913556, rs2989924, rs193922650, rs193922685, rs193922687, rs751160202, rs1421085, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829, rs6548238, rs7138803, rs7754840	28242765

Unknown
Disease name	Disease term	dbSNP ID	References
Pancreatitis	Pancreatitis	rs61734659	27840954