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MIR125A (microRNA 125a)
Gene
Gene Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
406910
Gene nameGene Name - the full gene name approved by the HGNC.
MicroRNA 125a
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
MIR125A
SynonymsGene synonyms aliases
MIRN125A, miRNA125A, mir-125a
ChromosomeChromosome number
19
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19q13.41
SummarySummary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0000993 Function RNA polymerase II complex binding IDA 25336585
GO:0001960 Process Negative regulation of cytokine-mediated signaling pathway ISS 30089723
GO:0003730 Function MRNA 3'-UTR binding IDA 30089723
GO:0005615 Component Extracellular space HDA 26646931
GO:0010628 Process Positive regulation of gene expression IDA 25116893
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Pathways Associated diseases
MIM
HGNC
e!Ensembl
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene Gene ontology Other IDs Pathways Associated diseases
 
KEGG
  
  MicroRNAs in cancer  
Associated diseases
Gene Gene ontology Other IDs Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Pulmonary fibrosis Pulmonary Fibrosis rs121918666, rs199422300, rs121917737, rs121917834, rs199422294, rs201159197, rs199422297, rs199422305, rs751381953, rs876661305, rs878853260, rs863223336, rs786205702, rs1555811762, rs1060502990, rs1555903332, rs1554038539, rs1554042899, rs938938578 30658076
Unknown
Disease name Disease term dbSNP ID References
Alveolitis Alveolitis, Fibrosing 30658076
Malignant mesothelioma Malignant mesothelioma 25756049

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