LPP (LIM domain containing preferred translocation partner in lipoma)
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Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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4026 |
Gene nameGene Name - the full gene name approved by the HGNC.
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LIM domain containing preferred translocation partner in lipoma |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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LPP |
SynonymsGene synonyms aliases
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- |
ChromosomeChromosome number
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3 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q27.3-q28 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in ce |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q93052 |
Protein name |
Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma) |
Protein function |
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00412 |
LIM |
416 → 473 |
LIM domain |
Domain |
PF00412 |
LIM |
476 → 532 |
LIM domain |
Domain |
PF00412 |
LIM |
536 → 600 |
LIM domain |
Domain |
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Sequence |
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Sequence length |
612 |
Interactions |
View interactions |
Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Arthritis |
Juvenile arthritis |
rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470 |
19565504 |
Asthma |
Asthma, Childhood asthma |
rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 |
30929738, 31619474, 21150878, 27182965, 21907864, 31036433, 31036433, 30929738 |
Autoimmune diseases |
Autoimmune Diseases, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2 |
rs41285370, rs869025224 |
21383967, 30595370, 30595370 |
Basal cell neoplasm |
Basal Cell Neoplasm, Basal Cell Cancer |
rs587776578, rs587776579, rs2117956624, rs2118419579, rs2118365442, rs2118041703, rs2136689212, rs2118336503, rs1587692888, rs267606984, rs878853849, rs1554695110, rs1064793921, rs1588605348, rs1588568813 |
27539887, 31174203, 31174203, 27539887 |
Carcinoma |
Basal cell carcinoma, Squamous cell carcinoma |
rs121912654, rs555607708, rs786202962, rs1564055259 |
31174203, 27539887, 31174203 |
Glaucoma |
Glaucoma, Open-Angle |
rs121918355, rs1566660365, rs1566635134, rs121918356, rs1566634475, rs28936700, rs55771538, rs28936701, rs104893622, rs55989760, rs72549387, rs104893628, rs2125316417, rs104893629, rs74315328, rs121909193, rs74315330, rs74315329, rs74315332, rs74315334, rs74315336, rs74315338, rs74315341, rs121909194, rs74315331, rs1558603396, rs387907175, rs587778873, rs587778875, rs104894979, rs137854895, rs766425037, rs72549380, rs148542782, rs541217363, rs753021890, rs771076928, rs56010818, rs777678299, rs1446110883, rs1573274915, rs1587545234, rs751768343, rs944452644 |
29891935 |
Hypothyroidism |
Hypothyroidism |
rs869320723, rs121908862, rs121908863, rs121908865, rs121908866, rs121908867, rs121908870, rs121908871, rs121908872, rs2140110277, rs121908881, rs121908884, rs121908885, rs786205080, rs1586182912, rs121917847, rs104893655, rs104893657, rs104893658, rs104893659, rs104893660, rs104893656, rs121917719, rs786204790, rs189261858, rs879255608, rs868197660, rs879255609, rs1586744173, rs1586182837, rs771222349, rs1587618417, rs1601844140, rs760832986, rs780982673, rs1603336347, rs1691155605 |
30595370 |
Inflammatory bowel disease |
Inflammatory Bowel Diseases |
rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs139868987, rs750447828, rs368138379, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468 |
28067908 |
Leukemia |
Leukemia, Myelocytic, Acute, Acute Myeloid Leukemia (AML-M2) |
rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601 |
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Multiple myeloma |
Multiple Myeloma |
rs11540652, rs78311289, rs121913482, rs397507340, rs121913343, rs121913240, rs121913529, rs730882018, rs1057517992, rs121913527, rs756183569, rs746646631, rs1574706907, rs372078034, rs745380962, rs751524927, rs1575079076, rs1575446356, rs1478603808, rs1578264146, rs1578673280, rs1579484570, rs1579491104, rs1171390403, rs1582867955, rs764264135, rs951047896, rs890521687, rs1581495906, rs1587941402, rs1003155450, rs1588299621, rs1591100766, rs1591693095, rs1029296641, rs1593107841, rs1208575764, rs1593835248, rs1594406727, rs1594966387, rs1595889508, rs1159294530, rs1597073318, rs1135402871, rs1599413207, rs1418268495, rs1212577459, rs1600394490, rs1455074519, rs1603113792, rs1603415028, rs1602247047, rs1603452612 |
28112199 |
Multiple sclerosis |
Multiple Sclerosis |
rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544 |
24076602, 22190364 |
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Allergic rhinitis |
Allergic rhinitis (disorder) |
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30013184 |
Allergic sensitization |
Allergic sensitization |
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23817571 |
Alopecia areata |
Alopecia Areata |
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25608926 |
Autoimmune thyroiditis |
Autoimmune thyroiditis |
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22922229 |
B-cell neoplasm |
Mature B-Cell Neoplasm |
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25279986 |
Celiac disease |
Celiac Disease |
rs2305764, rs35218876 |
22057235, 18311140, 20190752 |
Classical hodgkin lymphoma |
Nodular Sclerosis Classical Hodgkin Lymphoma |
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29196614 |
Crohn disease |
Crohn Disease |
rs2066847, rs2066844, rs886052047, rs5743265, rs111608429, rs104895438 |
28067908 |
Eczema |
Eczema |
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30595370 |
Graves disease |
Graves Disease |
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22922229 |
Hashimoto disease |
Hashimoto Disease |
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22922229 |
Hodgkin disease |
Hodgkin Disease |
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28112199, 29196614 |
Immune system diseases |
Immune System Diseases |
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21383967 |
Juvenile arthritis |
Juvenile psoriatic arthritis |
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19565504 |
Kidney failure |
Kidney Failure, Chronic |
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29124443 |
Lymphocytic leukemia |
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma |
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28112199, 26956414, 26956414, 28112199 |
Lupus erythematosus |
Lupus Erythematosus, Systemic |
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27399966 |
Myeloid leukemia |
Acute Myeloid Leukemia, M1 |
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Seronegative polyarthritis |
Polyarthritis, Juvenile, Rheumatoid Factor Negative |
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19565504 |
Polyarthritis, rheumatoid factor positive |
Polyarthritis, Juvenile, Rheumatoid Factor Positive |
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19565504 |
Respiratory tract diseases |
Respiratory Tract Diseases |
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30595370 |
Skin carcinoma |
Squamous cell carcinoma of skin |
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27424798 |
Still disease |
Juvenile-Onset Still Disease |
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19565504 |
Vitiligo |
Vitiligo |
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22951725, 21326295, 22561518, 27723757, 20410501 |
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