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LPP (LIM domain containing preferred translocation partner in lipoma)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
4026
Gene nameGene Name - the full gene name approved by the HGNC.
LIM domain containing preferred translocation partner in lipoma
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
LPP
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
3
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q27.3-q28
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in ce
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022848 hsa-miR-124-3p Microarray 18668037
MIRT237292 hsa-miR-142-3p Luciferase reporter assay 24361879
MIRT237292 hsa-miR-142-3p Luciferase reporter assay 24361879
MIRT237292 hsa-miR-142-3p Luciferase reporter assay 24361879
MIRT237292 hsa-miR-142-3p Luciferase reporter assay 24361879
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001725 Component Stress fiber IBA 21873635
GO:0005515 Function Protein binding IPI 15649318, 22665060
GO:0005634 Component Nucleus IEA
GO:0005829 Component Cytosol IDA
GO:0005886 Component Plasma membrane IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q93052
Protein name Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma)
Protein function May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00412 LIM
416 473
LIM domain
Domain
PF00412 LIM
476 532
LIM domain
Domain
PF00412 LIM
536 600
LIM domain
Domain
Sequence
MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKFAPVVAPKPKYNPYKQ
PGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAE
IDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTL
KPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSS
GQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGY
YAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPV
SAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCG
ENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTL
EQCNVCS
KPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKF
APRCSVCK
EPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSAR

IRVLTAKASTDL
Sequence length 612
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Arthritis Juvenile arthritis rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470 19565504
Asthma Asthma, Childhood asthma rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 30929738, 31619474, 21150878, 27182965, 21907864, 31036433, 31036433, 30929738
Autoimmune diseases Autoimmune Diseases, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2 rs41285370, rs869025224 21383967, 30595370, 30595370
Basal cell neoplasm Basal Cell Neoplasm, Basal Cell Cancer rs587776578, rs587776579, rs2117956624, rs2118419579, rs2118365442, rs2118041703, rs2136689212, rs2118336503, rs1587692888, rs267606984, rs878853849, rs1554695110, rs1064793921, rs1588605348, rs1588568813 27539887, 31174203, 31174203, 27539887
Unknown
Disease name Disease term dbSNP ID References
Allergic rhinitis Allergic rhinitis (disorder) 30013184
Allergic sensitization Allergic sensitization 23817571
Alopecia areata Alopecia Areata 25608926
Autoimmune thyroiditis Autoimmune thyroiditis 22922229

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