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LECT2 (leukocyte cell derived chemotaxin 2)
Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
3950
Gene nameGene Name - the full gene name approved by the HGNC.
Leukocyte cell derived chemotaxin 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
LECT2
SynonymsGene synonyms aliases
chm-II, chm2
ChromosomeChromosome number
5
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q31.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-indu
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT051767 hsa-let-7c-5p CLASH 23622248
MIRT2260520 hsa-miR-4438 CLIP-seq
MIRT2260521 hsa-miR-5095 CLIP-seq
MIRT2560531 hsa-miR-2054 CLIP-seq
MIRT2260520 hsa-miR-4438 CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0001501 Process Skeletal system development TAS 9545637
GO:0005515 Function Protein binding IPI 27334921
GO:0005615 Component Extracellular space TAS 9266841
GO:0005737 Component Cytoplasm TAS 9266841
GO:0005829 Component Cytosol IDA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID O14960
Protein name Leukocyte cell-derived chemotaxin-2 (LECT-2) (hLECT2)
Protein function Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation (PubMed:9524238). Does not show metalloendopeptidase activity (PubMed:27334921).
PDB 5B0H , 7N2I , 8G2V
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01551 Peptidase_M23
51 → 149
Peptidase family M23
 Family
Sequence
Sequence length 151
Interactions View interactions
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Causal
Disease name Disease term dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 30453282
Unknown
Disease name Disease term dbSNP ID References
Lung neoplasms Lung Neoplasms 30453282

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