Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3843 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Importin 5 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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IPO5 |
SynonymsGene synonyms aliases
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IMB3, KPNB3, Pse1, RANBP5, imp5 |
ChromosomeChromosome number
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13 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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13q32.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a het |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
O00410 |
Protein name |
Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5) |
Protein function |
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) t |
PDB |
6XTE
,
6XU2
,
9IM6
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Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF18808 |
Importin_rep_4 |
268 → 357 |
Importin repeat |
Repeat |
PF02985 |
HEAT |
400 → 430 |
HEAT repeat |
Repeat |
PF18829 |
Importin_rep_6 |
765 → 874 |
Importin repeat 6 |
Repeat |
PF02985 |
HEAT |
906 → 936 |
HEAT repeat |
Repeat |
PF18816 |
Importin_rep_5 |
1005 → 1061 |
Importin repeat |
Repeat |
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Sequence |
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Sequence length |
1097 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Lung adenocarcinoma |
Adenocarcinoma of lung (disorder) |
rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382 |
27602772 |
Schizophrenia |
Schizophrenia |
rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 |
20542336, 16644122, 15364420, 17458142 |
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