Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3775 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Potassium two pore domain channel subfamily K member 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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KCNK1 |
SynonymsGene synonyms aliases
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DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1 |
ChromosomeChromosome number
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1 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q42.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins fo |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
O00180 |
Protein name |
Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel K2P1) (Potassium channel KCNO1) |
Protein function |
Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues (PubMed:15820677, PubMed:21653227). Forms dimeric chan |
PDB |
3UKM
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Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF07885 |
Ion_trans_2 |
82 → 158 |
Ion channel |
Family |
PF07885 |
Ion_trans_2 |
190 → 271 |
Ion channel |
Family |
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Sequence |
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Sequence length |
336 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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