JAK1 (Janus kinase 1)

Gene

• Entrez ID: 3716
• Gene name: Janus kinase 1
• Gene symbol: JAK1
• Synonyms: AIIDE, JAK1A, JAK1B, JTK3
• Chromosome: 1
• Chromosome location: 1p31.3
• Summary: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs151047872	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs869312953	G>T	Likely-pathogenic	Missense variant, coding sequence variant
rs1057519753	C>A	Likely-pathogenic	Missense variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT000482	hsa-miR-17-5p	Luciferase reporter assay, Western blot	20299512
MIRT020460	hsa-miR-106b-5p	Microarray	17242205
MIRT021877	hsa-miR-128-3p	Microarray	17612493
MIRT046471	hsa-miR-15b-5p	CLASH	23622248
MIRT046312	hsa-miR-23b-3p	CLASH	23622248
MIRT053361	hsa-miR-9-5p	Microarray, qRT-PCR	23798388
MIRT020460	hsa-miR-106b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25307786
MIRT020460	hsa-miR-106b-5p	Luciferase reporter assay, qRT-PCR, Western blot	25307786
MIRT054776	hsa-miR-107	Luciferase reporter assay, qRT-PCR, Western blot, Coimmunoprecipitation, Chromatin immunoprecipitation, Immunofluorescence microscopy	24429361
MIRT020460	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT031081	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT020460	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT000482	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727412	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727411	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727410	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT031081	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT727408	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT727409	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT727407	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT727406	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT727405	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT731191	hsa-miR-373-3p	Immunoprecipitaion, qRT-PCR, Luciferase reporter assay, Western blot	25589644
MIRT731191	hsa-miR-373-3p	Immunoprecipitaion, qRT-PCR, Luciferase reporter assay, Western blot	25589644
MIRT727407	hsa-miR-30c-5p	Luciferase reporter assay	26826240
MIRT727407	hsa-miR-30c-5p	Luciferase reporter assay	26826240
MIRT000482	hsa-miR-17-5p	Luciferase reporter assay, Western blotting, Microarray, Immunohistochemistry (IHC), RNA-seq, qRT-PCR	32683798
MIRT737307	hsa-miR-126-3p	Luciferase reporter assay, Western blotting, Immunofluorescence, qRT-PCR	32554852
MIRT755646	hsa-miR-22-3p	Luciferase reporter assay, Western blotting, qRT-PCR	37824732
MIRT727408	hsa-miR-30a-5p	Luciferase reporter assay, qRT-PCR	38891028
MIRT1076007	hsa-miR-106a	CLIP-seq
MIRT1076008	hsa-miR-106b	CLIP-seq
MIRT1076009	hsa-miR-1179	CLIP-seq
MIRT1076010	hsa-miR-1245b-3p	CLIP-seq
MIRT1076011	hsa-miR-125a-3p	CLIP-seq
MIRT1076012	hsa-miR-1276	CLIP-seq
MIRT1076013	hsa-miR-1287	CLIP-seq
MIRT1076014	hsa-miR-1323	CLIP-seq
MIRT1076015	hsa-miR-142-5p	CLIP-seq
MIRT1076016	hsa-miR-148a	CLIP-seq
MIRT1076017	hsa-miR-148b	CLIP-seq
MIRT1076018	hsa-miR-152	CLIP-seq
MIRT1076019	hsa-miR-153	CLIP-seq
MIRT1076020	hsa-miR-1587	CLIP-seq
MIRT1076021	hsa-miR-17	CLIP-seq
MIRT1076022	hsa-miR-1825	CLIP-seq
MIRT1076023	hsa-miR-203	CLIP-seq
MIRT1076024	hsa-miR-2054	CLIP-seq
MIRT1076025	hsa-miR-20a	CLIP-seq
MIRT1076026	hsa-miR-20b	CLIP-seq
MIRT1076027	hsa-miR-299-3p	CLIP-seq
MIRT1076028	hsa-miR-30a	CLIP-seq
MIRT1076029	hsa-miR-30b	CLIP-seq
MIRT1076030	hsa-miR-30c	CLIP-seq
MIRT1076031	hsa-miR-30d	CLIP-seq
MIRT1076032	hsa-miR-30e	CLIP-seq
MIRT1076033	hsa-miR-3120-3p	CLIP-seq
MIRT1076034	hsa-miR-3124-3p	CLIP-seq
MIRT1076035	hsa-miR-3135b	CLIP-seq
MIRT1076036	hsa-miR-3149	CLIP-seq
MIRT1076037	hsa-miR-3164	CLIP-seq
MIRT1076038	hsa-miR-3173-3p	CLIP-seq
MIRT1076039	hsa-miR-3189-5p	CLIP-seq
MIRT1076040	hsa-miR-3192	CLIP-seq
MIRT1076041	hsa-miR-323-5p	CLIP-seq
MIRT1076042	hsa-miR-338-5p	CLIP-seq
MIRT1076043	hsa-miR-340	CLIP-seq
MIRT1076044	hsa-miR-3529	CLIP-seq
MIRT1076045	hsa-miR-3677-5p	CLIP-seq
MIRT1076046	hsa-miR-3688-3p	CLIP-seq
MIRT1076047	hsa-miR-3692	CLIP-seq
MIRT1076048	hsa-miR-379	CLIP-seq
MIRT1076049	hsa-miR-3944-5p	CLIP-seq
MIRT1076050	hsa-miR-3976	CLIP-seq
MIRT1076051	hsa-miR-421	CLIP-seq
MIRT1076052	hsa-miR-4261	CLIP-seq
MIRT1076053	hsa-miR-4276	CLIP-seq
MIRT1076054	hsa-miR-4310	CLIP-seq
MIRT1076055	hsa-miR-4311	CLIP-seq
MIRT1076056	hsa-miR-4314	CLIP-seq
MIRT1076057	hsa-miR-4422	CLIP-seq
MIRT1076058	hsa-miR-4437	CLIP-seq
MIRT1076059	hsa-miR-4451	CLIP-seq
MIRT1076060	hsa-miR-4453	CLIP-seq
MIRT1076061	hsa-miR-4457	CLIP-seq
MIRT1076062	hsa-miR-4464	CLIP-seq
MIRT1076063	hsa-miR-448	CLIP-seq
MIRT1076064	hsa-miR-4491	CLIP-seq
MIRT1076065	hsa-miR-4511	CLIP-seq
MIRT1076066	hsa-miR-4520a-3p	CLIP-seq
MIRT1076067	hsa-miR-4520b-3p	CLIP-seq
MIRT1076068	hsa-miR-4529-3p	CLIP-seq
MIRT1076069	hsa-miR-4536	CLIP-seq
MIRT1076070	hsa-miR-4538	CLIP-seq
MIRT1076071	hsa-miR-4646-5p	CLIP-seq
MIRT1076072	hsa-miR-4650-3p	CLIP-seq
MIRT1076073	hsa-miR-4657	CLIP-seq
MIRT1076074	hsa-miR-4674	CLIP-seq
MIRT1076075	hsa-miR-4676-5p	CLIP-seq
MIRT1076076	hsa-miR-4701-5p	CLIP-seq
MIRT1076077	hsa-miR-4709-5p	CLIP-seq
MIRT1076078	hsa-miR-4748	CLIP-seq
MIRT1076079	hsa-miR-4758-3p	CLIP-seq
MIRT1076080	hsa-miR-4773	CLIP-seq
MIRT1076081	hsa-miR-4796-3p	CLIP-seq
MIRT1076082	hsa-miR-495	CLIP-seq
MIRT1076083	hsa-miR-512-3p	CLIP-seq
MIRT1076084	hsa-miR-514	CLIP-seq
MIRT1076085	hsa-miR-514b-3p	CLIP-seq
MIRT1076086	hsa-miR-519a	CLIP-seq
MIRT1076087	hsa-miR-519b-3p	CLIP-seq
MIRT1076088	hsa-miR-519c-3p	CLIP-seq
MIRT1076089	hsa-miR-519d	CLIP-seq
MIRT1076090	hsa-miR-520f	CLIP-seq
MIRT1076091	hsa-miR-520g	CLIP-seq
MIRT1076092	hsa-miR-520h	CLIP-seq
MIRT1076093	hsa-miR-522	CLIP-seq
MIRT1076094	hsa-miR-548a-5p	CLIP-seq
MIRT1076095	hsa-miR-548aa	CLIP-seq
MIRT1076096	hsa-miR-548ab	CLIP-seq
MIRT1076097	hsa-miR-548ak	CLIP-seq
MIRT1076098	hsa-miR-548b-3p	CLIP-seq
MIRT1076099	hsa-miR-548b-5p	CLIP-seq
MIRT1076100	hsa-miR-548c-5p	CLIP-seq
MIRT1076101	hsa-miR-548d-5p	CLIP-seq
MIRT1076102	hsa-miR-548h	CLIP-seq
MIRT1076103	hsa-miR-548i	CLIP-seq
MIRT1076104	hsa-miR-548j	CLIP-seq
MIRT1076105	hsa-miR-548n	CLIP-seq
MIRT1076106	hsa-miR-548o	CLIP-seq
MIRT1076107	hsa-miR-548w	CLIP-seq
MIRT1076108	hsa-miR-548y	CLIP-seq
MIRT1076109	hsa-miR-552	CLIP-seq
MIRT1076110	hsa-miR-559	CLIP-seq
MIRT1076111	hsa-miR-568	CLIP-seq
MIRT1076112	hsa-miR-575	CLIP-seq
MIRT1076113	hsa-miR-583	CLIP-seq
MIRT1076114	hsa-miR-588	CLIP-seq
MIRT1076115	hsa-miR-642b	CLIP-seq
MIRT1076116	hsa-miR-765	CLIP-seq
MIRT1076117	hsa-miR-769-5p	CLIP-seq
MIRT1076118	hsa-miR-802	CLIP-seq
MIRT1076119	hsa-miR-876-3p	CLIP-seq
MIRT1076120	hsa-miR-93	CLIP-seq
MIRT2018893	hsa-miR-103a	CLIP-seq
MIRT1076007	hsa-miR-106a	CLIP-seq
MIRT1076008	hsa-miR-106b	CLIP-seq
MIRT1076011	hsa-miR-125a-3p	CLIP-seq
MIRT2018894	hsa-miR-1263	CLIP-seq
MIRT2018895	hsa-miR-1264	CLIP-seq
MIRT1076012	hsa-miR-1276	CLIP-seq
MIRT2018896	hsa-miR-139-5p	CLIP-seq
MIRT1076015	hsa-miR-142-5p	CLIP-seq
MIRT1076020	hsa-miR-1587	CLIP-seq
MIRT1076021	hsa-miR-17	CLIP-seq
MIRT1076025	hsa-miR-20a	CLIP-seq
MIRT1076026	hsa-miR-20b	CLIP-seq
MIRT2018897	hsa-miR-214	CLIP-seq
MIRT1076027	hsa-miR-299-3p	CLIP-seq
MIRT2018898	hsa-miR-302a	CLIP-seq
MIRT2018899	hsa-miR-302b	CLIP-seq
MIRT2018900	hsa-miR-302c	CLIP-seq
MIRT2018901	hsa-miR-302d	CLIP-seq
MIRT2018902	hsa-miR-302e	CLIP-seq
MIRT1076028	hsa-miR-30a	CLIP-seq
MIRT1076029	hsa-miR-30b	CLIP-seq
MIRT1076030	hsa-miR-30c	CLIP-seq
MIRT1076031	hsa-miR-30d	CLIP-seq
MIRT1076032	hsa-miR-30e	CLIP-seq
MIRT1076033	hsa-miR-3120-3p	CLIP-seq
MIRT1076034	hsa-miR-3124-3p	CLIP-seq
MIRT2018903	hsa-miR-3140-5p	CLIP-seq
MIRT2018904	hsa-miR-3143	CLIP-seq
MIRT1076036	hsa-miR-3149	CLIP-seq
MIRT2018905	hsa-miR-3160-5p	CLIP-seq
MIRT2018906	hsa-miR-3168	CLIP-seq
MIRT2018907	hsa-miR-3171	CLIP-seq
MIRT1076038	hsa-miR-3173-3p	CLIP-seq
MIRT2018908	hsa-miR-323b-5p	CLIP-seq
MIRT1076042	hsa-miR-338-5p	CLIP-seq
MIRT1076043	hsa-miR-340	CLIP-seq
MIRT2018909	hsa-miR-3619-5p	CLIP-seq
MIRT2018910	hsa-miR-3668	CLIP-seq
MIRT2018911	hsa-miR-3671	CLIP-seq
MIRT2018912	hsa-miR-3674	CLIP-seq
MIRT1076045	hsa-miR-3677-5p	CLIP-seq
MIRT1076046	hsa-miR-3688-3p	CLIP-seq
MIRT1076047	hsa-miR-3692	CLIP-seq
MIRT2018913	hsa-miR-372	CLIP-seq
MIRT2018914	hsa-miR-373	CLIP-seq
MIRT2018915	hsa-miR-3935	CLIP-seq
MIRT2018916	hsa-miR-3941	CLIP-seq
MIRT2018917	hsa-miR-3942-3p	CLIP-seq
MIRT1076050	hsa-miR-3976	CLIP-seq
MIRT1076051	hsa-miR-421	CLIP-seq
MIRT2018918	hsa-miR-4252	CLIP-seq
MIRT1076052	hsa-miR-4261	CLIP-seq
MIRT2018919	hsa-miR-4302	CLIP-seq
MIRT1076055	hsa-miR-4311	CLIP-seq
MIRT1076058	hsa-miR-4437	CLIP-seq
MIRT2018920	hsa-miR-4438	CLIP-seq
MIRT1076061	hsa-miR-4457	CLIP-seq
MIRT1076062	hsa-miR-4464	CLIP-seq
MIRT2018921	hsa-miR-4477a	CLIP-seq
MIRT1076063	hsa-miR-448	CLIP-seq
MIRT1076064	hsa-miR-4491	CLIP-seq
MIRT2018922	hsa-miR-4503	CLIP-seq
MIRT2018923	hsa-miR-4528	CLIP-seq
MIRT1076069	hsa-miR-4536	CLIP-seq
MIRT2018924	hsa-miR-4643	CLIP-seq
MIRT1076073	hsa-miR-4657	CLIP-seq
MIRT2018925	hsa-miR-466	CLIP-seq
MIRT2018926	hsa-miR-4668-5p	CLIP-seq
MIRT2018927	hsa-miR-4672	CLIP-seq
MIRT1076074	hsa-miR-4674	CLIP-seq
MIRT2018928	hsa-miR-4680-3p	CLIP-seq
MIRT1076076	hsa-miR-4701-5p	CLIP-seq
MIRT1076077	hsa-miR-4709-5p	CLIP-seq
MIRT2018929	hsa-miR-4720-3p	CLIP-seq
MIRT2018930	hsa-miR-4724-5p	CLIP-seq
MIRT1076078	hsa-miR-4748	CLIP-seq
MIRT2018931	hsa-miR-4774-5p	CLIP-seq
MIRT2018932	hsa-miR-4789-3p	CLIP-seq
MIRT2018933	hsa-miR-4804-3p	CLIP-seq
MIRT1076084	hsa-miR-514	CLIP-seq
MIRT1076085	hsa-miR-514b-3p	CLIP-seq
MIRT1076086	hsa-miR-519a	CLIP-seq
MIRT1076087	hsa-miR-519b-3p	CLIP-seq
MIRT1076088	hsa-miR-519c-3p	CLIP-seq
MIRT1076089	hsa-miR-519d	CLIP-seq
MIRT2018934	hsa-miR-520a-3p	CLIP-seq
MIRT2018935	hsa-miR-520b	CLIP-seq
MIRT2018936	hsa-miR-520c-3p	CLIP-seq
MIRT2018937	hsa-miR-520d-3p	CLIP-seq
MIRT2018938	hsa-miR-520e	CLIP-seq
MIRT1076090	hsa-miR-520f	CLIP-seq
MIRT1076091	hsa-miR-520g	CLIP-seq
MIRT1076092	hsa-miR-520h	CLIP-seq
MIRT1076093	hsa-miR-522	CLIP-seq
MIRT2018939	hsa-miR-526b	CLIP-seq
MIRT2018940	hsa-miR-545	CLIP-seq
MIRT1076109	hsa-miR-552	CLIP-seq
MIRT1076111	hsa-miR-568	CLIP-seq
MIRT2018941	hsa-miR-580	CLIP-seq
MIRT1076113	hsa-miR-583	CLIP-seq
MIRT1076114	hsa-miR-588	CLIP-seq
MIRT2018942	hsa-miR-607	CLIP-seq
MIRT2018943	hsa-miR-616	CLIP-seq
MIRT2018944	hsa-miR-619	CLIP-seq
MIRT1076115	hsa-miR-642b	CLIP-seq
MIRT2018945	hsa-miR-648	CLIP-seq
MIRT2018946	hsa-miR-656	CLIP-seq
MIRT2018947	hsa-miR-659	CLIP-seq
MIRT2018948	hsa-miR-761	CLIP-seq
MIRT1076116	hsa-miR-765	CLIP-seq
MIRT1076117	hsa-miR-769-5p	CLIP-seq
MIRT1076120	hsa-miR-93	CLIP-seq
MIRT2018893	hsa-miR-103a	CLIP-seq
MIRT1076009	hsa-miR-1179	CLIP-seq
MIRT2250763	hsa-miR-1207-3p	CLIP-seq
MIRT1076011	hsa-miR-125a-3p	CLIP-seq
MIRT1076012	hsa-miR-1276	CLIP-seq
MIRT1076014	hsa-miR-1323	CLIP-seq
MIRT1076015	hsa-miR-142-5p	CLIP-seq
MIRT1076016	hsa-miR-148a	CLIP-seq
MIRT1076017	hsa-miR-148b	CLIP-seq
MIRT1076018	hsa-miR-152	CLIP-seq
MIRT1076019	hsa-miR-153	CLIP-seq
MIRT1076020	hsa-miR-1587	CLIP-seq
MIRT2018897	hsa-miR-214	CLIP-seq
MIRT1076027	hsa-miR-299-3p	CLIP-seq
MIRT1076028	hsa-miR-30a	CLIP-seq
MIRT1076029	hsa-miR-30b	CLIP-seq
MIRT1076030	hsa-miR-30c	CLIP-seq
MIRT1076031	hsa-miR-30d	CLIP-seq
MIRT1076032	hsa-miR-30e	CLIP-seq
MIRT1076033	hsa-miR-3120-3p	CLIP-seq
MIRT2250764	hsa-miR-3123	CLIP-seq
MIRT2018903	hsa-miR-3140-5p	CLIP-seq
MIRT2018904	hsa-miR-3143	CLIP-seq
MIRT1076036	hsa-miR-3149	CLIP-seq
MIRT2018906	hsa-miR-3168	CLIP-seq
MIRT2018907	hsa-miR-3171	CLIP-seq
MIRT1076042	hsa-miR-338-5p	CLIP-seq
MIRT1076043	hsa-miR-340	CLIP-seq
MIRT2018909	hsa-miR-3619-5p	CLIP-seq
MIRT2250765	hsa-miR-3681	CLIP-seq
MIRT1076046	hsa-miR-3688-3p	CLIP-seq
MIRT2018917	hsa-miR-3942-3p	CLIP-seq
MIRT1076049	hsa-miR-3944-5p	CLIP-seq
MIRT1076051	hsa-miR-421	CLIP-seq
MIRT1076052	hsa-miR-4261	CLIP-seq
MIRT2250766	hsa-miR-4299	CLIP-seq
MIRT1076054	hsa-miR-4310	CLIP-seq
MIRT1076055	hsa-miR-4311	CLIP-seq
MIRT1076058	hsa-miR-4437	CLIP-seq
MIRT2018920	hsa-miR-4438	CLIP-seq
MIRT2250767	hsa-miR-4463	CLIP-seq
MIRT1076063	hsa-miR-448	CLIP-seq
MIRT1076064	hsa-miR-4491	CLIP-seq
MIRT2250768	hsa-miR-4494	CLIP-seq
MIRT1076065	hsa-miR-4511	CLIP-seq
MIRT1076069	hsa-miR-4536	CLIP-seq
MIRT1076073	hsa-miR-4657	CLIP-seq
MIRT2018926	hsa-miR-4668-5p	CLIP-seq
MIRT1076074	hsa-miR-4674	CLIP-seq
MIRT2018928	hsa-miR-4680-3p	CLIP-seq
MIRT1076077	hsa-miR-4709-5p	CLIP-seq
MIRT2250769	hsa-miR-4710	CLIP-seq
MIRT2018930	hsa-miR-4724-5p	CLIP-seq
MIRT1076080	hsa-miR-4773	CLIP-seq
MIRT2250770	hsa-miR-4792	CLIP-seq
MIRT2250771	hsa-miR-499a-5p	CLIP-seq
MIRT1076091	hsa-miR-520g	CLIP-seq
MIRT1076092	hsa-miR-520h	CLIP-seq
MIRT2018939	hsa-miR-526b	CLIP-seq
MIRT2018940	hsa-miR-545	CLIP-seq
MIRT2250772	hsa-miR-548a-3p	CLIP-seq
MIRT1076094	hsa-miR-548a-5p	CLIP-seq
MIRT1076095	hsa-miR-548aa	CLIP-seq
MIRT1076096	hsa-miR-548ab	CLIP-seq
MIRT1076097	hsa-miR-548ak	CLIP-seq
MIRT1076098	hsa-miR-548b-3p	CLIP-seq
MIRT1076099	hsa-miR-548b-5p	CLIP-seq
MIRT1076100	hsa-miR-548c-5p	CLIP-seq
MIRT1076101	hsa-miR-548d-5p	CLIP-seq
MIRT2250773	hsa-miR-548e	CLIP-seq
MIRT2250774	hsa-miR-548f	CLIP-seq
MIRT2250775	hsa-miR-548g	CLIP-seq
MIRT1076102	hsa-miR-548h	CLIP-seq
MIRT1076103	hsa-miR-548i	CLIP-seq
MIRT1076104	hsa-miR-548j	CLIP-seq
MIRT1076105	hsa-miR-548n	CLIP-seq
MIRT1076106	hsa-miR-548o	CLIP-seq
MIRT1076107	hsa-miR-548w	CLIP-seq
MIRT1076108	hsa-miR-548y	CLIP-seq
MIRT1076109	hsa-miR-552	CLIP-seq
MIRT1076110	hsa-miR-559	CLIP-seq
MIRT1076111	hsa-miR-568	CLIP-seq
MIRT2250776	hsa-miR-570	CLIP-seq
MIRT2018941	hsa-miR-580	CLIP-seq
MIRT1076113	hsa-miR-583	CLIP-seq
MIRT2018946	hsa-miR-656	CLIP-seq
MIRT2018948	hsa-miR-761	CLIP-seq
MIRT1076117	hsa-miR-769-5p	CLIP-seq
MIRT1076118	hsa-miR-802	CLIP-seq
MIRT2250777	hsa-miR-885-3p	CLIP-seq
MIRT2018903	hsa-miR-3140-5p	CLIP-seq
MIRT2018906	hsa-miR-3168	CLIP-seq
MIRT2018907	hsa-miR-3171	CLIP-seq
MIRT2018917	hsa-miR-3942-3p	CLIP-seq
MIRT2018918	hsa-miR-4252	CLIP-seq
MIRT2018920	hsa-miR-4438	CLIP-seq
MIRT2018928	hsa-miR-4680-3p	CLIP-seq
MIRT2018930	hsa-miR-4724-5p	CLIP-seq
MIRT2018939	hsa-miR-526b	CLIP-seq
MIRT2018941	hsa-miR-580	CLIP-seq
MIRT1076115	hsa-miR-642b	CLIP-seq
MIRT1076117	hsa-miR-769-5p	CLIP-seq
MIRT1076012	hsa-miR-1276	CLIP-seq
MIRT2018896	hsa-miR-139-5p	CLIP-seq
MIRT2430178	hsa-miR-3125	CLIP-seq
MIRT1076042	hsa-miR-338-5p	CLIP-seq
MIRT2430179	hsa-miR-3916	CLIP-seq
MIRT2018916	hsa-miR-3941	CLIP-seq
MIRT2018919	hsa-miR-4302	CLIP-seq
MIRT1076055	hsa-miR-4311	CLIP-seq
MIRT2018921	hsa-miR-4477a	CLIP-seq
MIRT2018922	hsa-miR-4503	CLIP-seq
MIRT2018924	hsa-miR-4643	CLIP-seq
MIRT2018925	hsa-miR-466	CLIP-seq
MIRT2430180	hsa-miR-4666-5p	CLIP-seq
MIRT2018927	hsa-miR-4672	CLIP-seq
MIRT2018931	hsa-miR-4774-5p	CLIP-seq
MIRT2018932	hsa-miR-4789-3p	CLIP-seq
MIRT2430181	hsa-miR-4789-5p	CLIP-seq
MIRT2430182	hsa-miR-550a	CLIP-seq
MIRT1076113	hsa-miR-583	CLIP-seq
MIRT2018944	hsa-miR-619	CLIP-seq
MIRT2018945	hsa-miR-648	CLIP-seq
MIRT1076020	hsa-miR-1587	CLIP-seq
MIRT2018903	hsa-miR-3140-5p	CLIP-seq
MIRT2018907	hsa-miR-3171	CLIP-seq
MIRT2018918	hsa-miR-4252	CLIP-seq
MIRT1076058	hsa-miR-4437	CLIP-seq
MIRT1076074	hsa-miR-4674	CLIP-seq
MIRT2018928	hsa-miR-4680-3p	CLIP-seq
MIRT2018930	hsa-miR-4724-5p	CLIP-seq
MIRT1076115	hsa-miR-642b	CLIP-seq
MIRT1076117	hsa-miR-769-5p	CLIP-seq
MIRT2554216	hsa-miR-1202	CLIP-seq
MIRT2554217	hsa-miR-1227	CLIP-seq
MIRT2554218	hsa-miR-1251	CLIP-seq
MIRT1076011	hsa-miR-125a-3p	CLIP-seq
MIRT2018894	hsa-miR-1263	CLIP-seq
MIRT1076012	hsa-miR-1276	CLIP-seq
MIRT2554219	hsa-miR-1297	CLIP-seq
MIRT2554220	hsa-miR-1304	CLIP-seq
MIRT2018896	hsa-miR-139-5p	CLIP-seq
MIRT2554221	hsa-miR-140-3p	CLIP-seq
MIRT1076020	hsa-miR-1587	CLIP-seq
MIRT2554222	hsa-miR-193a-5p	CLIP-seq
MIRT2554223	hsa-miR-23a	CLIP-seq
MIRT2554224	hsa-miR-23b	CLIP-seq
MIRT2554225	hsa-miR-23c	CLIP-seq
MIRT2554226	hsa-miR-26a	CLIP-seq
MIRT2554227	hsa-miR-26b	CLIP-seq
MIRT1076034	hsa-miR-3124-3p	CLIP-seq
MIRT2430178	hsa-miR-3125	CLIP-seq
MIRT2018903	hsa-miR-3140-5p	CLIP-seq
MIRT1076037	hsa-miR-3164	CLIP-seq
MIRT2018907	hsa-miR-3171	CLIP-seq
MIRT1076038	hsa-miR-3173-3p	CLIP-seq
MIRT2554228	hsa-miR-3194-5p	CLIP-seq
MIRT1076042	hsa-miR-338-5p	CLIP-seq
MIRT2554229	hsa-miR-3616-3p	CLIP-seq
MIRT2554230	hsa-miR-3653	CLIP-seq
MIRT2554231	hsa-miR-3658	CLIP-seq
MIRT2018912	hsa-miR-3674	CLIP-seq
MIRT2250765	hsa-miR-3681	CLIP-seq
MIRT2554232	hsa-miR-3682-3p	CLIP-seq
MIRT1076046	hsa-miR-3688-3p	CLIP-seq
MIRT1076047	hsa-miR-3692	CLIP-seq
MIRT2554233	hsa-miR-371-3p	CLIP-seq
MIRT2554234	hsa-miR-371b-3p	CLIP-seq
MIRT2430179	hsa-miR-3916	CLIP-seq
MIRT2018915	hsa-miR-3935	CLIP-seq
MIRT2018916	hsa-miR-3941	CLIP-seq
MIRT2018917	hsa-miR-3942-3p	CLIP-seq
MIRT2554235	hsa-miR-3972	CLIP-seq
MIRT1076051	hsa-miR-421	CLIP-seq
MIRT2018918	hsa-miR-4252	CLIP-seq
MIRT1076052	hsa-miR-4261	CLIP-seq
MIRT1076053	hsa-miR-4276	CLIP-seq
MIRT2018919	hsa-miR-4302	CLIP-seq
MIRT1076055	hsa-miR-4311	CLIP-seq
MIRT2554236	hsa-miR-4317	CLIP-seq
MIRT1076058	hsa-miR-4437	CLIP-seq
MIRT1076061	hsa-miR-4457	CLIP-seq
MIRT2554237	hsa-miR-4465	CLIP-seq
MIRT2018921	hsa-miR-4477a	CLIP-seq
MIRT2250768	hsa-miR-4494	CLIP-seq
MIRT2018922	hsa-miR-4503	CLIP-seq
MIRT1076065	hsa-miR-4511	CLIP-seq
MIRT1076066	hsa-miR-4520a-3p	CLIP-seq
MIRT1076067	hsa-miR-4520b-3p	CLIP-seq
MIRT1076068	hsa-miR-4529-3p	CLIP-seq
MIRT2554238	hsa-miR-455-5p	CLIP-seq
MIRT2018924	hsa-miR-4643	CLIP-seq
MIRT2018925	hsa-miR-466	CLIP-seq
MIRT2430180	hsa-miR-4666-5p	CLIP-seq
MIRT2018927	hsa-miR-4672	CLIP-seq
MIRT1076074	hsa-miR-4674	CLIP-seq
MIRT2018928	hsa-miR-4680-3p	CLIP-seq
MIRT2554239	hsa-miR-4684-3p	CLIP-seq
MIRT2554240	hsa-miR-4694-3p	CLIP-seq
MIRT1076077	hsa-miR-4709-5p	CLIP-seq
MIRT2554241	hsa-miR-4721	CLIP-seq
MIRT2018930	hsa-miR-4724-5p	CLIP-seq
MIRT1076080	hsa-miR-4773	CLIP-seq
MIRT2018931	hsa-miR-4774-5p	CLIP-seq
MIRT2018932	hsa-miR-4789-3p	CLIP-seq
MIRT2430181	hsa-miR-4789-5p	CLIP-seq
MIRT1076082	hsa-miR-495	CLIP-seq
MIRT2554242	hsa-miR-498	CLIP-seq
MIRT2250771	hsa-miR-499a-5p	CLIP-seq
MIRT2554243	hsa-miR-515-3p	CLIP-seq
MIRT2554244	hsa-miR-519e	CLIP-seq
MIRT1076093	hsa-miR-522	CLIP-seq
MIRT2250772	hsa-miR-548a-3p	CLIP-seq
MIRT1076094	hsa-miR-548a-5p	CLIP-seq
MIRT1076096	hsa-miR-548ab	CLIP-seq
MIRT2554245	hsa-miR-548ac	CLIP-seq
MIRT2554246	hsa-miR-548ae	CLIP-seq
MIRT2554247	hsa-miR-548aj	CLIP-seq
MIRT1076097	hsa-miR-548ak	CLIP-seq
MIRT2554248	hsa-miR-548am	CLIP-seq
MIRT1076098	hsa-miR-548b-3p	CLIP-seq
MIRT1076099	hsa-miR-548b-5p	CLIP-seq
MIRT1076100	hsa-miR-548c-5p	CLIP-seq
MIRT2554249	hsa-miR-548d-3p	CLIP-seq
MIRT1076101	hsa-miR-548d-5p	CLIP-seq
MIRT2250773	hsa-miR-548e	CLIP-seq
MIRT2250774	hsa-miR-548f	CLIP-seq
MIRT2250775	hsa-miR-548g	CLIP-seq
MIRT1076102	hsa-miR-548h	CLIP-seq
MIRT1076103	hsa-miR-548i	CLIP-seq
MIRT1076104	hsa-miR-548j	CLIP-seq
MIRT1076105	hsa-miR-548n	CLIP-seq
MIRT2554250	hsa-miR-548u	CLIP-seq
MIRT1076107	hsa-miR-548w	CLIP-seq
MIRT2554251	hsa-miR-548x	CLIP-seq
MIRT1076108	hsa-miR-548y	CLIP-seq
MIRT2554252	hsa-miR-548z	CLIP-seq
MIRT2430182	hsa-miR-550a	CLIP-seq
MIRT1076109	hsa-miR-552	CLIP-seq
MIRT1076110	hsa-miR-559	CLIP-seq
MIRT2250776	hsa-miR-570	CLIP-seq
MIRT1076113	hsa-miR-583	CLIP-seq
MIRT1076115	hsa-miR-642b	CLIP-seq
MIRT2018945	hsa-miR-648	CLIP-seq
MIRT1076116	hsa-miR-765	CLIP-seq
MIRT2554253	hsa-miR-767-5p	CLIP-seq
MIRT1076117	hsa-miR-769-5p	CLIP-seq
MIRT1076118	hsa-miR-802	CLIP-seq
MIRT2554254	hsa-miR-891b	CLIP-seq
MIRT2554218	hsa-miR-1251	CLIP-seq
MIRT1076011	hsa-miR-125a-3p	CLIP-seq
MIRT2018894	hsa-miR-1263	CLIP-seq
MIRT1076012	hsa-miR-1276	CLIP-seq
MIRT2554219	hsa-miR-1297	CLIP-seq
MIRT2018896	hsa-miR-139-5p	CLIP-seq
MIRT2554221	hsa-miR-140-3p	CLIP-seq
MIRT1076020	hsa-miR-1587	CLIP-seq
MIRT2554222	hsa-miR-193a-5p	CLIP-seq
MIRT2554223	hsa-miR-23a	CLIP-seq
MIRT2554224	hsa-miR-23b	CLIP-seq
MIRT2554225	hsa-miR-23c	CLIP-seq
MIRT2554226	hsa-miR-26a	CLIP-seq
MIRT2554227	hsa-miR-26b	CLIP-seq
MIRT1076034	hsa-miR-3124-3p	CLIP-seq
MIRT2430178	hsa-miR-3125	CLIP-seq
MIRT2018903	hsa-miR-3140-5p	CLIP-seq
MIRT1076037	hsa-miR-3164	CLIP-seq
MIRT2018907	hsa-miR-3171	CLIP-seq
MIRT1076038	hsa-miR-3173-3p	CLIP-seq
MIRT1076042	hsa-miR-338-5p	CLIP-seq
MIRT2018912	hsa-miR-3674	CLIP-seq
MIRT2250765	hsa-miR-3681	CLIP-seq
MIRT2554232	hsa-miR-3682-3p	CLIP-seq
MIRT1076046	hsa-miR-3688-3p	CLIP-seq
MIRT1076047	hsa-miR-3692	CLIP-seq
MIRT2554233	hsa-miR-371-3p	CLIP-seq
MIRT2554234	hsa-miR-371b-3p	CLIP-seq
MIRT2430179	hsa-miR-3916	CLIP-seq
MIRT2018915	hsa-miR-3935	CLIP-seq
MIRT2018916	hsa-miR-3941	CLIP-seq
MIRT2018917	hsa-miR-3942-3p	CLIP-seq
MIRT1076051	hsa-miR-421	CLIP-seq
MIRT2018918	hsa-miR-4252	CLIP-seq
MIRT1076052	hsa-miR-4261	CLIP-seq
MIRT1076053	hsa-miR-4276	CLIP-seq
MIRT2018919	hsa-miR-4302	CLIP-seq
MIRT1076055	hsa-miR-4311	CLIP-seq
MIRT2554236	hsa-miR-4317	CLIP-seq
MIRT1076058	hsa-miR-4437	CLIP-seq
MIRT1076061	hsa-miR-4457	CLIP-seq
MIRT2554237	hsa-miR-4465	CLIP-seq
MIRT2018921	hsa-miR-4477a	CLIP-seq
MIRT2250768	hsa-miR-4494	CLIP-seq
MIRT2018922	hsa-miR-4503	CLIP-seq
MIRT1076066	hsa-miR-4520a-3p	CLIP-seq
MIRT1076067	hsa-miR-4520b-3p	CLIP-seq
MIRT1076068	hsa-miR-4529-3p	CLIP-seq
MIRT2018924	hsa-miR-4643	CLIP-seq
MIRT2018925	hsa-miR-466	CLIP-seq
MIRT2430180	hsa-miR-4666-5p	CLIP-seq
MIRT2018927	hsa-miR-4672	CLIP-seq
MIRT1076074	hsa-miR-4674	CLIP-seq
MIRT2018928	hsa-miR-4680-3p	CLIP-seq
MIRT2554239	hsa-miR-4684-3p	CLIP-seq
MIRT2554240	hsa-miR-4694-3p	CLIP-seq
MIRT1076077	hsa-miR-4709-5p	CLIP-seq
MIRT2018930	hsa-miR-4724-5p	CLIP-seq
MIRT2018932	hsa-miR-4789-3p	CLIP-seq
MIRT2430181	hsa-miR-4789-5p	CLIP-seq
MIRT1076082	hsa-miR-495	CLIP-seq
MIRT2554242	hsa-miR-498	CLIP-seq
MIRT2250771	hsa-miR-499a-5p	CLIP-seq
MIRT2554243	hsa-miR-515-3p	CLIP-seq
MIRT2554244	hsa-miR-519e	CLIP-seq
MIRT1076093	hsa-miR-522	CLIP-seq
MIRT2250772	hsa-miR-548a-3p	CLIP-seq
MIRT1076094	hsa-miR-548a-5p	CLIP-seq
MIRT1076096	hsa-miR-548ab	CLIP-seq
MIRT2554245	hsa-miR-548ac	CLIP-seq
MIRT2554246	hsa-miR-548ae	CLIP-seq
MIRT2554247	hsa-miR-548aj	CLIP-seq
MIRT1076097	hsa-miR-548ak	CLIP-seq
MIRT2554248	hsa-miR-548am	CLIP-seq
MIRT1076099	hsa-miR-548b-5p	CLIP-seq
MIRT1076100	hsa-miR-548c-5p	CLIP-seq
MIRT2554249	hsa-miR-548d-3p	CLIP-seq
MIRT1076101	hsa-miR-548d-5p	CLIP-seq
MIRT2250773	hsa-miR-548e	CLIP-seq
MIRT2250774	hsa-miR-548f	CLIP-seq
MIRT2250775	hsa-miR-548g	CLIP-seq
MIRT1076102	hsa-miR-548h	CLIP-seq
MIRT1076103	hsa-miR-548i	CLIP-seq
MIRT1076104	hsa-miR-548j	CLIP-seq
MIRT1076105	hsa-miR-548n	CLIP-seq
MIRT2554250	hsa-miR-548u	CLIP-seq
MIRT1076107	hsa-miR-548w	CLIP-seq
MIRT2554251	hsa-miR-548x	CLIP-seq
MIRT1076108	hsa-miR-548y	CLIP-seq
MIRT2554252	hsa-miR-548z	CLIP-seq
MIRT2430182	hsa-miR-550a	CLIP-seq
MIRT1076109	hsa-miR-552	CLIP-seq
MIRT1076110	hsa-miR-559	CLIP-seq
MIRT2250776	hsa-miR-570	CLIP-seq
MIRT1076113	hsa-miR-583	CLIP-seq
MIRT1076115	hsa-miR-642b	CLIP-seq
MIRT2018945	hsa-miR-648	CLIP-seq
MIRT1076116	hsa-miR-765	CLIP-seq
MIRT2554253	hsa-miR-767-5p	CLIP-seq
MIRT1076117	hsa-miR-769-5p	CLIP-seq
MIRT1076118	hsa-miR-802	CLIP-seq
MIRT2554254	hsa-miR-891b	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
BRCA1	Unknown	11163768

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	TAS
GO:0004713	Function	Protein tyrosine kinase activity	EXP	1386289, 8232552, 10825200
GO:0004713	Function	Protein tyrosine kinase activity	TAS
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	TAS
GO:0005131	Function	Growth hormone receptor binding	IBA	21873635
GO:0005131	Function	Growth hormone receptor binding	ISS	10502458
GO:0005515	Function	Protein binding	IPI	7759950, 16273093, 16710296, 21220115, 21679692, 25065853, 26175413
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IDA	10502458
GO:0005737	Component	Cytoplasm	IDA	10502458
GO:0005768	Component	Endosome	TAS
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0006468	Process	Protein phosphorylation	TAS	1848670
GO:0016020	Component	Membrane	IEA
GO:0018108	Process	Peptidyl-tyrosine phosphorylation	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	IBA	21873635
GO:0019221	Process	Cytokine-mediated signaling pathway	TAS
GO:0019903	Function	Protein phosphatase binding	IPI	11909529
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	24882218
GO:0031730	Function	CCR5 chemokine receptor binding	IEA
GO:0034112	Process	Positive regulation of homotypic cell-cell adhesion	IMP	21679692
GO:0035556	Process	Intracellular signal transduction	TAS	8232552
GO:0035722	Process	Interleukin-12-mediated signaling pathway	TAS
GO:0035723	Process	Interleukin-15-mediated signaling pathway	TAS
GO:0038110	Process	Interleukin-2-mediated signaling pathway	IDA	11909529
GO:0038110	Process	Interleukin-2-mediated signaling pathway	TAS
GO:0038111	Process	Interleukin-7-mediated signaling pathway	TAS
GO:0038113	Process	Interleukin-9-mediated signaling pathway	TAS
GO:0038114	Process	Interleukin-21-mediated signaling pathway	TAS
GO:0046677	Process	Response to antibiotic	IDA	16280321
GO:0046872	Function	Metal ion binding	IEA
GO:0060333	Process	Interferon-gamma-mediated signaling pathway	TAS
GO:0060334	Process	Regulation of interferon-gamma-mediated signaling pathway	TAS
GO:0060337	Process	Type I interferon signaling pathway	TAS
GO:0070102	Process	Interleukin-6-mediated signaling pathway	TAS
GO:0070106	Process	Interleukin-27-mediated signaling pathway	TAS
GO:0070757	Process	Interleukin-35-mediated signaling pathway	TAS
GO:0150105	Process	Protein localization to cell-cell junction	IMP	21679692
GO:1903672	Process	Positive regulation of sprouting angiogenesis	IGI	20299512

Other IDs

• MIM: 147795
• HGNC: 6190
• e!Ensembl: ENSG00000162434

Protein

• UniProt ID: P23458
• Protein name: Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
• Protein function: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:16239216, PubMed:28111307, PubMed:32750333, PubMed:7615558, PubMed:8232552). Kinase partner for the interleukin (IL)-2 receptor (PubMed:1190952
• PDB: 3EYG, 3EYH, 4E4L, 4E4N, 4E5W, 4EHZ, 4EI4, 4FK6, 4GS0, 4I5C, 4IVB, 4IVC, 4IVD, 4K6Z, 4K77, 4L00, 4L01, 5E1E, 5HX8, 5IXD, 5IXI, 5KHW, 5KHX, 5L04, 5WO4, 6AAH, 6BBU, 6C7Y, 6DBN, 6ELR, 6GGH, 6HZU, 6N77, 6N78, 6N79, 6N7A, 6N7B, 6N7C, 6N7D, 6RSB, 6RSC, 6RSD, 6RSE, 6RSH, 6SM8, 6SMB, 6TPE, 6TPF, 6W8L, 8EXJ, 8S85
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF18379	FERM_F1	36 → 129	FERM F1 ubiquitin-like domain	Domain
  PF18377	FERM_F2	147 → 277	FERM F2 acyl-CoA binding protein-like domain	Domain
  PF17887	Jak1_Phl	284 → 421	Jak1 pleckstrin homology-like domain	Domain
  PF07714	PK_Tyr_Ser-Thr	583 → 845	Protein tyrosine and serine/threonine kinase	Domain
  PF07714	PK_Tyr_Ser-Thr	875 → 1149	Protein tyrosine and serine/threonine kinase	Domain

• Sequence:

  MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
  CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
  DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
  DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
  NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
  WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
  EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
  HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
  CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
  KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
  TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
  VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
  LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
  TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
  IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
  TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
  SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
  DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
  DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
  SFQNLIEGFEALLK

• Sequence length: 1154

Pathways

KEGG:

EGFR tyrosine kinase inhibitor resistance
PI3K-Akt signaling pathway
Necroptosis
Osteoclast differentiation
Signaling pathways regulating pluripotency of stem cells
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
JAK-STAT signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation
Leishmaniasis
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Measles
Human cytomegalovirus infection
Influenza A
Human papillomavirus infection
Human T-cell leukemia virus 1 infection
Kaposi sarcoma-associated herpesvirus infection
Herpes simplex virus 1 infection
Epstein-Barr virus infection
Coronavirus disease - COVID-19
Pathways in cancer
Viral carcinogenesis
Pancreatic cancer
PD-L1 expression and PD-1 checkpoint pathway in cancer

Reactome:

Interleukin-6 signaling
MAPK3 (ERK1) activation
MAPK1 (ERK2) activation
ISG15 antiviral mechanism
Interleukin-7 signaling
Other interleukin signaling
RAF/MAP kinase cascade
Interleukin-10 signaling
Interleukin-4 and Interleukin-13 signaling
IL-6-type cytokine receptor ligand interactions
Interferon gamma signaling
Regulation of IFNG signaling
Interleukin-20 family signaling
Interleukin-15 signaling
Interleukin-35 Signalling
Interleukin-9 signaling
Interleukin-2 signaling
Interleukin-12 signaling
Interleukin-27 signaling
Interleukin-21 signaling
Interferon alpha/beta signaling
Interleukin receptor SHC signaling
Regulation of IFNA signaling

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Autoimmune diseases	Autoimmune Diseases, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2	rs41285370, rs869025224	30595370
Hypothyroidism	Hypothyroidism	rs869320723, rs121908862, rs121908863, rs121908865, rs121908866, rs121908867, rs121908870, rs121908871, rs121908872, rs2140110277, rs121908881, rs121908884, rs121908885, rs786205080, rs1586182912, rs121917847, rs104893655, rs104893657, rs104893658, rs104893659, rs104893660, rs104893656, rs121917719, rs786204790, rs189261858, rs879255608, rs868197660, rs879255609, rs1586744173, rs1586182837, rs771222349, rs1587618417, rs1601844140, rs760832986, rs780982673, rs1603336347, rs1691155605	30595370
Leukemia	Leukemia, Myelocytic, Acute, Leukemia, Acute, X-Linked	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601	21436584, 21680795, 27903959, 19139102
Lymphoblastic leukemia	Precursor Cell Lymphoblastic Leukemia Lymphoma	rs387906351, rs104894562, rs398122513, rs398122840, rs398123063, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699, rs1597567692, rs1597567985, rs1438890364, rs1288977950, rs1597552140, rs1597566356, rs1597566726, rs1597568117, rs2069719445, rs2069729948, rs2070018439, rs745708044, rs1169577591
Multiple congenital anomalies	Multiple congenital anomalies	rs1057517732	25356970
Polycythemia vera	Polycythemia Vera	rs77375493	16239216
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	29610475

Unknown
Disease name	Disease term	dbSNP ID	References
Diabetic nephropathy	Diabetic Nephropathy		26305897
Eczema	Eczema		30595370
Hypereosinophilic syndrome	Hypereosinophilic syndrome	rs181854060, rs77524207, rs150577828, rs139236922, rs35597368, rs36035373, rs200042995, rs149951350, rs139913632, rs200033396, rs541057765, rs61735622, rs199827643, rs142498442, rs138519829, rs754092062, rs35805947, rs140725151, rs55966236, rs56026726, rs149031291, rs761924292, rs55830582, rs199902153, rs56384252, rs138150216, rs55996208, rs148629782, rs55947416, rs2229307, rs4358459, rs1873778, rs10028020, rs2228230, rs7685117, rs1799767, rs886059444, rs754623338, rs375050626, rs141346675, rs886059451, rs886059452, rs757111915, rs886059456, rs55710909, rs565989173, rs748063948, rs886059459, rs777478254, rs10034498, rs886059460, rs547925170, rs145549583, rs886059443, rs151259376, rs142492533, rs563016888, rs886059446, rs555347387, rs750090756, rs3690, rs566508858, rs56288633, rs1565664, rs145328998, rs187821520, rs368579295, rs574665425, rs886059461, rs886059462, rs533627398, rs183431225, rs78405886, rs886059445, rs886059447, rs878854837, rs771421611, rs55681376, rs7680422, rs886059450, rs886059448, rs886059449, rs12511976, rs373134586, rs557191329, rs34529347, rs886059457, rs554089461, rs544503522, rs138584193, rs752208389, rs886059458, rs184179322, rs149631103, rs377126983, rs886059463, rs137930765, rs61735621, rs778161572, rs1060504254, rs190260215, rs373948582, rs773679384, rs774431464, rs1218651787, rs778510648, rs779173667	28111307
Lymphoblastic leukemia with lymphomatous features	Acute lymphoblastic leukemia with lymphomatous features		22955920, 19139102, 19470474, 19838194, 21680795, 20167706
Prostatic neoplasms	Prostatic Neoplasms		29610475