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INPP1 (inositol polyphosphate-1-phosphatase)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
3628
Gene nameGene Name - the full gene name approved by the HGNC.
Inositol polyphosphate-1-phosphatase
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
INPP1
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q32.2
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisp
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT1067106 hsa-miR-128 CLIP-seq
MIRT1067107 hsa-miR-27a CLIP-seq
MIRT1067108 hsa-miR-27b CLIP-seq
MIRT1067109 hsa-miR-4328 CLIP-seq
MIRT1067110 hsa-miR-513a-5p CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0004441 Function Inositol-1,4-bisphosphate 1-phosphatase activity IBA 21873635
GO:0005515 Function Protein binding IPI 26871637
GO:0005829 Component Cytosol TAS
GO:0006796 Process Phosphate-containing compound metabolic process TAS 8390685
GO:0007165 Process Signal transduction TAS 8390685
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P49441
Protein name Inositol polyphosphate 1-phosphatase (IPP) (IPPase) (EC 3.1.3.57)
Protein function Mg(2+)-dependent phosphatase that catalyzes the hydrolysis of the 1-position phosphate from inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate and participates in inositol phosphate metabolism.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00459 Inositol_P
74 → 381
Inositol monophosphatase family
 Family
Sequence
Sequence length 399
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
Reactome
  Inositol phosphate metabolism
Metabolic pathways
Phosphatidylinositol signaling system 		  Synthesis of IP2, IP, and Ins in the cytosol
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Autism Autistic Disorder rs121964908, rs121912597, rs2710102, rs7794745, rs142990298, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699, rs1553510219, rs1684182454, rs1559060428, rs1553510677, rs1576352885, rs1574152522, rs1574152672, rs1696658542, rs1751123722, rs1750373491, rs1751075634 14627686
Unknown
Disease name Disease term dbSNP ID References
Bipolar disorder Bipolar Disorder 16787706, 10780272, 9682271, 11901356

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